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  4. IMPG2 Antibody, Biotin conjugated

IMPG2 Antibody, Biotin conjugated

  • 中文名稱：
    IMPG2兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA011704LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) IMPG2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    IMPG2
  • 別名：
    IMPG2 antibody; IPM200 antibody; Interphotoreceptor matrix proteoglycan 2 antibody; Interphotoreceptor matrix proteoglycan of 200 kDa antibody; IPM 200 antibody; Sialoprotein associated with cones and rods proteoglycan antibody; Spacrcan antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Interphotoreceptor matrix proteoglycan 2 protein (616-759AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds heparin.
  • 基因功能參考文獻：
    1. IMPG1 and IMPG2 are new causal genes of vitelliform dystrophy, involved in 8% of our families. PMID: 25085631
    2. Mutations in IMPG2 cause a severe form of retinitis pigmentosa with symptoms manifesting in the first 2 decades of life. PMID: 24876279
    3. identification of IMPG2 mutations in autosomal-recessive retinitis pigmentosa; data show that mutations in a structural component of the interphotoreceptor matrix can cause autosomal-recessive retinitis pigmentosa PMID: 20673862
    4. IPM 200 represents the second member of a novel family of retinal proteoglycans suspected to be involved in retinal adhesion and photoreceptor cell survival PMID: 10542133
  • 相關疾病：
    Retinitis pigmentosa 56 (RP56); Macular dystrophy, vitelliform, 5 (VMD5)
  • 亞細胞定位：
    Photoreceptor outer segment membrane; Single-pass type I membrane protein. Photoreceptor inner segment membrane; Single-pass type I membrane protein. Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix.
  • 組織特異性：
    Expressed in the retina (at protein level). Expressed by photoreceptors of the interphotoreceptor matrix (IPM) surrounding both rods and cones (at protein level). IPM occupies the subretinal space between the apices of the retinal pigment epithelium and t
  • 數據庫鏈接：

    HGNC: 18362

    OMIM: 607056

    KEGG: hsa:50939

    STRING: 9606.ENSP00000193391

    UniGene: Hs.209249



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