在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Interferon-induced guanylate-binding protein 2 (GBP2)

  • 中文名稱:
    人GBP2重組蛋白
  • 貨號:
    CSB-YP009298HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人GBP2重組蛋白
  • 貨號:
    CSB-EP009298HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人GBP2重組蛋白
  • 貨號:
    CSB-EP009298HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人GBP2重組蛋白
  • 貨號:
    CSB-BP009298HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人GBP2重組蛋白
  • 貨號:
    CSB-MP009298HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    GBP2Guanylate-binding protein 2; EC 3.6.5.-; GTP-binding protein 2; GBP-2; HuGBP-2; Guanine nucleotide-binding protein 2; Interferon-induced guanylate-binding protein 2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-588
  • 氨基酸序列
    MAPEINLPGP MSLIDNTKGQ LVVNPEALKI LSAITQPVVV VAIVGLYRTG KSYLMNKLAG KKNGFSLGST VKSHTKGIWM WCVPHPKKPE HTLVLLDTEG LGDIEKGDNE NDSWIFALAI LLSSTFVYNS MGTINQQAMD QLHYVTELTD RIKANSSPGN NSVDDSADFV SFFPAFVWTL RDFTLELEVD GEPITADDYL ELSLKLRKGT DKKSKSFNDP RLCIRKFFPK RKCFVFDWPA PKKYLAHLEQ LKEEELNPDF IEQVAEFCSY ILSHSNVKTL SGGIPVNGPR LESLVLTYVN AISSGDLPCM ENAVLALAQI ENSAAVEKAI AHYEQQMGQK VQLPTETLQE LLDLHRDSER EAIEVFMKNS FKDVDQMFQR KLGAQLEARR DDFCKQNSKA SSDCCMALLQ DIFGPLEEDV KQGTFSKPGG YRLFTQKLQE LKNKYYQVPR KGIQAKEVLK KYLESKEDVA DALLQTDQSL SEKEKAIEVE RIKAESAEAA KKMLEEIQKK NEEMMEQKEK SYQEHVKQLT EKMERDRAQL MAEQEKTLAL KLQEQERLLK EGFENESKRL QKDIWDIQMR SKSLEPIC
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions, but the major reaction product is GDP. Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.
  • 基因功能參考文獻:
    1. Study presents the first demonstration that GBP2 inhibits mitochondrial fission and cell metastasis in breast cancer cells both in vitro and in vivo. PMID: 29072687
    2. Low GBP2 expression is associated with metastasis in breast cancer. PMID: 23001506
    3. Downregulation of MIR-433 is associated with myeloproliferative neoplasms. PMID: 22864358
    4. The in vivo localization of GBP-2 at cellular membranes is regulated by isoprenylation and dimerization. PMID: 21151871
    5. Guanylate-binding protein 2 mRNA in peripheral blood leukocytes may have a role in acute cellular rejection after liver transplantation PMID: 19912588
    6. Sky1p utilizes the same docking groove to bind yeast SR-like protein Gbp2p and phosphorylates all three serines present in a contiguous RS dipeptide stretch PMID: 17517895
    7. GBP-2 is regulated by p53 and may have a role in esophageal squamous cell carcinomas PMID: 19003964

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus membrane. Membrane; Lipid-anchor.
  • 蛋白家族:
    TRAFAC class dynamin-like GTPase superfamily, GB1/RHD3-type GTPase family, GB1 subfamily
  • 數據庫鏈接:

    HGNC: 4183

    OMIM: 600412

    KEGG: hsa:2634

    STRING: 9606.ENSP00000359497

    UniGene: Hs.386567



主站蜘蛛池模板: 国产一区二区精品久久岳| 6080亚洲人久久精品| 曰批免费视频播放免费| 中文字幕网伦射乱中文| 国产精品香蕉在线观看| 日本免码va在线看免费| 中文字幕精品亚洲人成在线| 亚洲 欧美 变态 另类 综合| 精品无码国产自产拍在线观看蜜| 日产精品高潮呻吟av久久| 亚洲综合无码无在线观看| 国产精品久久久久无码av1| 成年美女黄网站色大片免费看| 蜜桃精品成人影片| 无码人妻人妻经典| 亚洲va中文字幕无码久久不卡| 国内精品久久久久久久久电影网| 在线欧美中文字幕农村电影| 国产成人精选在线观看不卡| 七妺福利精品导航大全| 成人精品视频一区二区三区尤物| 蜜桃久久精品成人无码av| 日日噜狠狠噜天天噜av| 蜜臀久久99精品久久久久久小说| 亚洲欧美日韩视频高清专区 | 亚洲国产欧美在线观看| 日韩免费无码一区二区视频| 久久视频这里只精品99| 久久精品一区二区av999| 日本夜爽爽一区二区三区| 天天综合亚洲色在线精品| 免费午夜理论不卡| 夜夜高潮夜夜爽夜夜爱| 香蕉午夜福利院| 无套内射chinesehd熟女| 强行无套内谢大学生初次 | 久久精品国产亚洲一区二区| 亚洲va在线va天堂xx xx| 久热这里只有精品12| 国产人久久人人人人爽| 成在人线av无码免费看|