在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GBP2 Recombinant Monoclonal Antibody

  • 中文名稱:
    GBP2 Recombinant Monoclonal Antibody
  • 貨號:
    CSB-RA009298MA1HU
  • 規格:
    ¥1320
  • 圖片:
    • Western Blot
      Positive WB detected in: U-251MG whole cell lysate(20μg)
      All lanes: GBP2 antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/40000 dilution
      Predicted band size: 67 kDa
      Observed band size: 67 kDa
      Exposure time:2min
    • Immunofluorescence staining of Hela cell with CSB-RA009298MA1HU at 1:30 counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Human IgG(H+L).
    • Overlay Peak curve showing A431 cells stained with CSB-RA009298MA1HU (red line) at 1:100. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100 for?10min. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*106cells) for 45min at 4℃. The secondary antibody used was Fluorescein (FITC) AffiniPure Goat Anti-Human IgG, Fcγ fragment specific at 1:200 dilution for 35min at 4℃.Control antibody (green line) was human IgG1 (1ug/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    GBP2Guanylate-binding protein 2 antibody; EC 3.6.5.- antibody; GTP-binding protein 2 antibody; GBP-2 antibody; HuGBP-2 antibody; Guanine nucleotide-binding protein 2 antibody; Interferon-induced guanylate-binding protein 2 antibody
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human GBP2 protein
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Monoclonal
  • 抗體亞型:
    hIgG1
  • 純化方式:
    Affinity-chromatography
  • 克隆號:
    1H6F9
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IF, FC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:50-1:200
    FC 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions, but the major reaction product is GDP. Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.
  • 基因功能參考文獻:
    1. Study presents the first demonstration that GBP2 inhibits mitochondrial fission and cell metastasis in breast cancer cells both in vitro and in vivo. PMID: 29072687
    2. Low GBP2 expression is associated with metastasis in breast cancer. PMID: 23001506
    3. Downregulation of MIR-433 is associated with myeloproliferative neoplasms. PMID: 22864358
    4. The in vivo localization of GBP-2 at cellular membranes is regulated by isoprenylation and dimerization. PMID: 21151871
    5. Guanylate-binding protein 2 mRNA in peripheral blood leukocytes may have a role in acute cellular rejection after liver transplantation PMID: 19912588
    6. Sky1p utilizes the same docking groove to bind yeast SR-like protein Gbp2p and phosphorylates all three serines present in a contiguous RS dipeptide stretch PMID: 17517895
    7. GBP-2 is regulated by p53 and may have a role in esophageal squamous cell carcinomas PMID: 19003964

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus membrane. Membrane; Lipid-anchor.
  • 蛋白家族:
    TRAFAC class dynamin-like GTPase superfamily, GB1/RHD3-type GTPase family, GB1 subfamily
  • 數據庫鏈接:

    HGNC: 4183

    OMIM: 600412

    KEGG: hsa:2634

    STRING: 9606.ENSP00000359497

    UniGene: Hs.386567



主站蜘蛛池模板: 久久综合亚洲色hezyo国产| 性色欲情网站iwww九文堂| 亚洲综合中文字幕无线码| 伊人久久大香线蕉亚洲五月天| 成人免费国产精品视频| 国产免费丝袜调教视频| 中文字幕中文有码在线| 蜜臀视频一区二区在线播放| 中文字幕无码免费久久99| 亚洲爆乳无码精品aaa片蜜桃| 国产欧美日韩专区发布| 侵犯强奷高清无码| 无遮挡很爽很污很黄的网站| 青青草97国产精品免费观看| 揉捏奶头高潮呻吟视频| 成人性欧美丨区二区三区 | 国产免费mv大全视频网站| 亚洲中文字幕在线精品2021| 欧美 日韩 国产 另类 图片区 | 国产精品久久久久av| 午夜爱爱免费视频体验区| 中文字幕日韩人妻无码| 亚洲国产成人乱码| 狠狠躁夜夜躁人人爽天天| 亚洲偷精品国产五月丁香麻豆| 在教室伦流澡到高潮hgl视频| 亚洲第一se情网站| 少妇饥渴偷公乱av在线观看涩爱| 亚洲国产日韩制服在线观看| 窝窝午夜理论片影院| 国产探花在线精品一区二区| 日本少妇内射视频播放舔| 99热在线精品免费全部my| 波多野结衣办公室双飞| 精品国产一区二区三区四区在线看 | 未满十八18禁止午夜免费网站 | 久久久久成人精品| 性生交大片免费看l| 中文字幕久精品免费视频| 大地资源在线观看官网第三页| 国外av无码精品国产精品|