在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Insulin receptor-related protein (INSRR), partial

  • 中文名稱:
    人INSRR重組蛋白
  • 貨號:
    CSB-YP011755HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人INSRR重組蛋白
  • 貨號:
    CSB-EP011755HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人INSRR重組蛋白
  • 貨號:
    CSB-EP011755HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人INSRR重組蛋白
  • 貨號:
    CSB-BP011755HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人INSRR重組蛋白
  • 貨號:
    CSB-MP011755HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    INSRR; INSRR_HUMAN; Insulin Receptor R; Insulin receptor related receptor precursor; Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain; insulin receptor-related receptor; IR R; IR related receptor; IR-related receptor; IRR; Sir r; Sirr
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.
  • 基因功能參考文獻:
    1. the extensive glycosylation of FnIII-2/3 provides steric hindrance for the alkali-induced rearrangement of the IRR ectodomain. PMID: 29156593
    2. IRR activation involves two separate centers of pH-dependent rearrangements that act synergistically to induce a major conformational change in the IRR molecule, resulting in internal kinase domains rapprochement and autophosphorylation. PMID: 25597417
    3. IRR activation is not based on a single residue deprotonation in the IRR ectodomain but rather involves synergistic conformational changes at multiple points. PMID: 24121506
    4. Insulin receptor-related receptor as an extracellular pH sensor involved in the regulation of acid-base balance. (Review) PMID: 23220417
    5. Analysis of structural determinants of alkali sensor IRR positive cooperativity. PMID: 23824460
    6. IRR mRNA expression was found in 25 (51%) neuroblastomas and correlated with stages 1, 2, 3, and 4S disease and with age. PMID: 14654552
    7. Phosphotyrosine detection revealed a lack in the constitutive activation of the IRR described for analogous constructs of the two other members of the family PMID: 15629149
    8. The IRR gene is expressed in the same ovarian compartment, IRR mRNA content increases strikingly in these cells in the afternoon of the first proestrus. PMID: 16195402

    顯示更多

    收起更多

  • 亞細胞定位:
    Membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily
  • 數據庫鏈接:

    HGNC: 6093

    OMIM: 147671

    KEGG: hsa:3645

    STRING: 9606.ENSP00000357178

    UniGene: Hs.248138



主站蜘蛛池模板: 99久久婷婷国产综合精品青草免费| 蜜臀aⅴ国产精品久久久国产老师| 国产精品自在欧美一区| www夜片内射视频日韩精品成人| 色狠狠一区二区三区香蕉| 无码专区 人妻系列 在线| 边吃奶边添下面好爽| 国产第一页浮力影院入口| 色噜噜亚洲男人的天堂www| 色欲天天婬色婬香综合网| 国产精品久久久| 国产午夜福利精品一区二区三区| 国产有奶水哺乳期无码avav| 女人被狂c到高潮视频网站| 亚洲欧美综合精品成人网| 久久亚洲色www成人不卡| 女人被爽到呻吟gif动态图视看 | 天堂一区人妻无码| 亚洲熟妇久久国产精品| 无码av中文一区二区三区| 国产99视频精品免费观看9| 少妇人妻偷人精品视频| 亚洲精品国产suv一区88| 中文字日产幕乱五区| 日本亚洲欧美高清专区vr专区 | 天天爱天天做久久狼狼| 免费三级网站| 久久久噜噜噜久久中文字幕色伊伊| 国产精品成人亚洲777| 精品国产免费观看久久久| 午夜少妇性影院私人影院在线| 疯狂三人交性欧美| 国模无码一区二区三区| 国产天美传媒性色av出轨| 深夜国产成人福利在线观看| 野花社区视频www官网| 十八岁污网站在线观看| 久久精品国产久精国产果冻传媒| 性欧美俄罗斯乱妇| 性少妇无码播放| 成人网站免费观看|