在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

INSRR Antibody, FITC conjugated

  • 中文名稱:
    INSRR兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA011755LC01HU
  • 規(guī)格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) INSRR Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    INSRR antibody; INSRR_HUMAN antibody; Insulin Receptor R antibody; Insulin receptor related receptor precursor antibody; Insulin receptor-related protein alpha chain antibody; Insulin receptor-related protein beta chain antibody; insulin receptor-related receptor antibody; IR R antibody; IR related receptor antibody; IR-related receptor antibody; IRR antibody; Sir r antibody; Sirr antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Insulin receptor-related protein (747-921AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Antigen Affinity purified & Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.
  • 基因功能參考文獻:
    1. the extensive glycosylation of FnIII-2/3 provides steric hindrance for the alkali-induced rearrangement of the IRR ectodomain. PMID: 29156593
    2. IRR activation involves two separate centers of pH-dependent rearrangements that act synergistically to induce a major conformational change in the IRR molecule, resulting in internal kinase domains rapprochement and autophosphorylation. PMID: 25597417
    3. IRR activation is not based on a single residue deprotonation in the IRR ectodomain but rather involves synergistic conformational changes at multiple points. PMID: 24121506
    4. Insulin receptor-related receptor as an extracellular pH sensor involved in the regulation of acid-base balance. (Review) PMID: 23220417
    5. Analysis of structural determinants of alkali sensor IRR positive cooperativity. PMID: 23824460
    6. IRR mRNA expression was found in 25 (51%) neuroblastomas and correlated with stages 1, 2, 3, and 4S disease and with age. PMID: 14654552
    7. Phosphotyrosine detection revealed a lack in the constitutive activation of the IRR described for analogous constructs of the two other members of the family PMID: 15629149
    8. The IRR gene is expressed in the same ovarian compartment, IRR mRNA content increases strikingly in these cells in the afternoon of the first proestrus. PMID: 16195402

    顯示更多

    收起更多

  • 亞細胞定位:
    Membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily
  • 數據庫鏈接:

    HGNC: 6093

    OMIM: 147671

    KEGG: hsa:3645

    STRING: 9606.ENSP00000357178

    UniGene: Hs.248138



主站蜘蛛池模板: 大战熟女丰满人妻av| 香蕉久久国产av一区二区| 少妇性饥渴无码a区免费| 国产乱子伦精品无码专区| 欧美精品乱码99久久蜜桃| 女人被男人桶30分钟无遮挡动态图| 在线偷着国产精选视频| 午夜人成免费视频| 狠狠躁天天躁中文字幕无码| 国模小黎自慰gogo人体| 无码精品国产一区二区三区免费| 人人做人人爽国产视| 人人爽久久久噜噜噜婷婷| 久久久久久无码av成人影院| 精品国产av 无码一区二区三区| 无码精品一区二区三区在线| 拍国产乱人伦偷精品视频 | 麻豆国产成人av高清在线| 精品久久香蕉国产线看观看亚洲 | 欧洲熟妇色xxxx欧美老妇老头多毛| 男人天堂2018亚洲男人天堂| 亚洲hdmi高清线| 一本一本久久aa综合精品| 精品无码日韩一区二区三区不卡| 国产亚洲精品一区在线播放| 女女女女女裸体处开bbb| 国内揄拍高清国内精品对白 | 乱子伦一区二区三区| 一区二区无码免费视频网站| 麻豆精品偷拍人妻在线网址| 一本加勒比波多野结衣| 国产精品无码久久久久成人影院| 欧美成人a天堂片在线观看| 中文无码av在线亚洲电影| 理论片午午伦夜理片影院99| 好紧好爽好湿别拔出来视频男男| 日本熟妇hdsex视频| 天堂8在线天堂资源bt| 又紧又大又爽精品一区二区| 狠狠色成人一区二区三区| 羞涩的丰满人妻40p|