在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Hydroxyacylglutathione hydrolase, mitochondrial (HAGH)

  • 中文名稱:
    人HAGH重組蛋白
  • 貨號:
    CSB-YP624118HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人HAGH重組蛋白
  • 貨號:
    CSB-EP624118HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人HAGH重組蛋白
  • 貨號:
    CSB-EP624118HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人HAGH重組蛋白
  • 貨號:
    CSB-BP624118HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人HAGH重組蛋白
  • 貨號:
    CSB-MP624118HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    HAGH; GLO2; HAGH1Hydroxyacylglutathione hydrolase; mitochondrial; EC 3.1.2.6; Glyoxalase II; Glx II
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    14-308
  • 氨基酸序列
    AALGAAC ARRGLGPALL GVFCHTDLRK NLTVDEGTMK VEVLPALTDN YMYLVIDDET KEAAIVDPVQ PQKVVDAARK HGVKLTTVLT THHHWDHAGG NEKLVKLESG LKVYGGDDRI GALTHKITHL STLQVGSLNV KCLATPCHTS GHICYFVSKP GGSEPPAVFT GDTLFVAGCG KFYEGTADEM CKALLEVLGR LPPDTRVYCG HEYTINNLKF ARHVEPGNAA IREKLAWAKE KYSIGEPTVP STLAEEFTYN PFMRVREKTV QQHAGETDPV TTMRAVRREK DQFKMPRD
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
  • 基因功能參考文獻:
    1. Down regulation of Glyoxalase II was observed in cases of diabetic retinopathy as compared to controls. PMID: 29950256
    2. The critical role of glyoxalases as regulators of tumorigenesis in the prostate through modulation of various critical signaling pathways, and an overview of the current knowledge on glyoxalases in bladder, kidney and testis cancers is reviewed. (GLO1, GLO2) PMID: 29385039
    3. epidermal expression stronger in older skin donors PMID: 26914966
    4. Glo2, together with Glo1, represents a novel mechanism in prostate cancer progression as part of a pathway driven by PTEN/PI3K/AKT/mTOR signaling. PMID: 27696457
    5. This article reports for the first time a possible additional role of Glo2 that, after interacting with a target protein, is able to promote S-glutathionylation. PMID: 27935136
    6. This study suggested that HAGH, rs11859266 and rs3743852 showed significant associations with schizophrenia in males at allelic and genotype levels. PMID: 25645869
    7. No association between genetic variants of the HAGH gene and autism spectrum disorder was found. PMID: 24671236
    8. hydroxyacylglutathione hydrolase (HAGH) gene encodes both cytosolic and mitochondrial forms of glyoxalase II PMID: 15117945
    9. Overexpression of glyoxalase II is associated with kidney tumor PMID: 16803681
    10. Data show that the GLX2 gene, which encodes glyoxalase II enzyme, is up-regulated by p63 and p73. PMID: 16831876
    11. In androgen-dependent prostate cancer cells, testosterone upregulates GLO2 mRNA levels. In androgen-independent prostate cancer cells, it downregulates GLO2 mRNA. PMID: 18344682
    12. Human glyoxalase II contains an Fe(II)Zn(II) center but is active as a mononuclear Zn(II) enzyme PMID: 19413286

    顯示更多

    收起更多

  • 亞細胞定位:
    [Isoform 1]: Mitochondrion matrix.; [Isoform 2]: Cytoplasm.
  • 蛋白家族:
    Metallo-beta-lactamase superfamily, Glyoxalase II family
  • 組織特異性:
    Expressed in liver and kidney.
  • 數據庫鏈接:

    HGNC: 4805

    OMIM: 138760

    KEGG: hsa:3029

    STRING: 9606.ENSP00000380514

    UniGene: Hs.157394



主站蜘蛛池模板: 人妻体内射精一区二区三区| 亚洲无线码中文字幕在线| 亚洲乱码中文字幕综合234 | 99久久人妻精品免费一区| 国产成人免费无码视频在线观看| 亚洲熟妇色xxxxx亚洲| 久久精品人人槡人妻人人玩av | 99视频有精品视频高清| 成人做爰www网站视频下载| 国产成人精品久久| 欧性猛交ⅹxxx乱大交| 精品偷拍被偷拍在线观看| 亚洲欧洲美洲在线观看| 成年美女黄网站色大片免费看| 奇米影视777四色狠狠| 丰满的少妇xxxxx人| 最近最新中文字幕高清免费| 亚洲一卡二卡三卡四卡| 阳茎伸入女人阳道视频| 亚洲国产精品无码久久久蜜芽| 无码人妻精品一二三区免费| 天天爽天天爽天天爽| 国产精品 自在自线| 亚洲综合欧美在线一区在线播放| 国产精品盗摄!偷窥盗摄| 亚洲国产婷婷香蕉久久久久久| 无码aⅴ精品一区二区三区浪潮 | 尤物av无码国产在线看| 午夜精品影视国产一区在线麻豆 | 97久久超碰中文字幕| 无码高潮爽到爆的喷水视频 | 99久热re在线精品视频| 2019国产品在线视频| 亚洲 欧美日韩 综合 国产| 久久综合九色综合97网| 无码人妻一区、二区、三区免费视频 | 国产精品亚洲片夜色在线| 熟妇玩小男视频在线| 欧美亚洲日本高清不卡| 精品一区二区三区免费播放| 人妻熟女av一区二区三区|