在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Humanin (MT-RNR2)

  • 中文名稱:
    人MT-RNR2重組蛋白
  • 貨號:
    CSB-YP814209HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人MT-RNR2重組蛋白
  • 貨號:
    CSB-EP814209HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人MT-RNR2重組蛋白
  • 貨號:
    CSB-BP814209HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    MT-RNR2; HN; Humanin; Humanin mitochondrial; HNM
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length
  • 表達區域:
    1-24
  • 氨基酸序列
    MAPRGFSCLL LLTSEIDLPV KRRA
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective effect by interacting with a receptor complex composed of IL6ST/GP130, IL27RA/WSX1 and CNTFR. Also acts as a ligand for G-protein coupled receptors FPR2/FPRL1 and FPR3/FPRL2. Inhibits amyloid-beta protein 40 fibril formation. Also inhibits amyloid-beta protein 42 fibril formation. Suppresses apoptosis by binding to BAX and preventing the translocation of BAX from the cytosol to mitochondria. Also suppresses apoptosis by binding to BID and inhibiting the interaction of BID with BAX and BAK which prevents oligomerization of BAX and BAK and suppresses release of apoptogenic proteins from mitochondria. Forms fibers with BAX and also with BID, inducing BAX and BID conformational changes and sequestering them into the fibers which prevents their activation. Can also suppress apoptosis by interacting with BIM isoform BimEL, inhibiting BimEL-induced activation of BAX, blocking oligomerization of BAX and BAK, and preventing release of apoptogenic proteins from mitochondria. Plays a role in up-regulation of anti-apoptotic protein BIRC6/APOLLON, leading to inhibition of neuronal cell death. Binds to IGFBP3 and specifically blocks IGFBP3-induced cell death. Competes with importin KPNB1 for binding to IGFBP3 which is likely to block IGFBP3 nuclear import. Induces chemotaxis of mononuclear phagocytes via FPR2/FPRL1. Reduces aggregation and fibrillary formation by suppressing the effect of APP on mononuclear phagocytes and acts by competitively inhibiting the access of FPR2 to APP. Protects retinal pigment epithelium (RPE) cells against oxidative stress-induced and endoplasmic reticulum (ER) stress-induced apoptosis. Promotes mitochondrial biogenesis in RPE cells following oxidative stress and promotes STAT3 phosphorylation which leads to inhibition of CASP3 release. Also reduces CASP4 levels in RPE cells, suppresses ER stress-induced mitochondrial superoxide production and plays a role in up-regulation of mitochondrial glutathione. Reduces testicular hormone deprivation-induced apoptosis of germ cells at the nonandrogen-sensitive stages of the seminiferous epithelium cycle. Protects endothelial cells against free fatty acid-induced inflammation by suppressing oxidative stress, reducing expression of TXNIP and inhibiting activation of the NLRP3 inflammasome which inhibits expression of proinflammatory cytokines IL1B and IL18. Protects against high glucose-induced endothelial cell dysfunction by mediating activation of ERK5 which leads to increased expression of transcription factor KLF2 and prevents monocyte adhesion to endothelial cells. Inhibits the inflammatory response in astrocytes. Increases the expression of PPARGC1A/PGC1A in pancreatic beta cells which promotes mitochondrial biogenesis. Increases insulin sensitivity.
  • 亞細胞定位:
    Secreted. Cytoplasm. Cell projection, cilium, flagellum. Nucleus. Mitochondrion.
  • 蛋白家族:
    Humanin family
  • 組織特異性:
    Expressed in testis, seminal plasma and sperm (at protein level). Higher seminal plasma levels are associated with normospermia than with oligospermia, asthenospermia or oligoasthenospermia (at protein level). Higher sperm levels are associated with normo
  • 數據庫鏈接:

    HGNC: 7471

    OMIM: 606120



主站蜘蛛池模板: 国产99视频精品专区| 精品亚洲成a人片在线观看少妇| 国产伦精品一区二区三区妓女下载 | 2020久久超碰国产精品最新 | 国产精品亚洲а∨天堂| 精品人妻va出轨中文字幕| 国产精品成人午夜久久| 国产精品人成视频免费999 | 亚洲日本乱码中文在线电影| 国产丝袜视频一区二区三区| 无码人妻精品一区二区蜜桃网站 | 久久无码超清激情av| 日韩国产亚洲高清在线久草| 中文字幕亚洲综合久久菠萝蜜| 国产亚洲人成a在线v网站| 国内精品久久久久久影院| 青青青国产在线视频在线观看| 欧美阿v高清资源在线| 自拍偷自拍亚洲精品情侣| 国产精品久久毛片av大全日韩| 天天爽天天摸天天碰| 久久国产精品老女人| 精品欧美一区二区三区久久久| 护士脱了内裤让我爽了一夜视频| 欧洲日本一线二线三线区本庄铃| 伊人久久大香线蕉无码不卡| 午夜精品一区二区三区免费视频| 成人性生交大片免费看vr| 亚洲成av人片在线观看天堂无 | 亚洲熟妇丰满大屁股熟妇| 亚洲精品成人片在线播放| 亚洲a成人无码网站在线| 无码人妻久久一区二区三区app | 午夜精品电影你懂的| 国产无遮挡a片又黄又爽漫画| 欧美成人片一区二区三区| 久久综合激激的五月天| 欧美人成视频在线视频| 亚洲成a人片在线观看日本| 全黄性性激高免费视频| 国产在线看片免费人成视频|