在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Homeobox protein OTX1 (OTX1)

  • 中文名稱:
    人OTX1重組蛋白
  • 貨號:
    CSB-YP017298HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人OTX1重組蛋白
  • 貨號:
    CSB-EP017298HU
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人OTX1重組蛋白
  • 貨號:
    CSB-EP017298HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人OTX1重組蛋白
  • 貨號:
    CSB-BP017298HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人OTX1重組蛋白
  • 貨號:
    CSB-MP017298HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    FLJ38361; Homeobox protein OTX 1; Homeobox protein OTX1; MGC15736; Orthodenticle 1; Orthodenticle homeobox 1; Orthodenticle homolog 1; Orthodenticle1; Otx 1; otx1; OTX1_HUMAN
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full length protein
  • 表達(dá)區(qū)域:
    1-354
  • 氨基酸序列
    MMSYLKQPPY GMNGLGLAGP AMDLLHPSVG YPATPRKQRR ERTTFTRSQL DVLEALFAKT RYPDIFMREE VALKINLPES RVQVWFKNRR AKCRQQQQSG SGTKSRPAKK KSSPVRESSG SESSGQFTPP AVSSSASSSS SASSSSANPA AAAAAGLGGN PVAAASSLST PAASSIWSPA SISPGSAPAS VSVPEPLAAP SNTSCMQRSV AAGAATAAAS YPMSYGQGGS YGQGYPTPSS SYFGGVDCSS YLAPMHSHHH PHQLSPMAPS SMAGHHHHHP HAHHPLSQSS GHHHHHHHHH HQGYGGSGLA FNSADCLDYK EPGAAAASSA WKLNFNSPDC LDYKDQASWR FQVL
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.
  • 基因功能參考文獻:
    1. High OTX1 expression is associated with gastric cancer. PMID: 30066897
    2. We speculate that ACTR2 and MEIS1 might respectively play a role in the pathogenesis of the observed deafness and cardiomyopathy...the patient carrying a 2p14p15 deletion including OTX1 had normal kidneys and genitalia, thus confirming that OTX1 haploinsufficiency is not invariably associated with genitourinary defects. PMID: 28599093
    3. OTX1 and OTX2 genes might have a role in the pathogenesis of different types of sinonasal neoplasms. PMID: 28348423
    4. Genitalia defects in these patients could result from the effect of OTX1. PMID: 25203062
    5. overexpression of OTX1 results in accumulation of colorectal cancer (CRC) cell proliferation and invasion in vitro and tumor growth in vivo, whereas ablation of OTX1 expression inhibits the proliferative and invasive capability of CRC cell lines PMID: 24388989
    6. XPO1 and OXT1 may contribute to ASD in 2p15-p16.1 deletion cases and non-deletion cases of ASD mapping to this chromosome region. PMID: 21750575
    7. established that the p53 protein directly induces OTX1 expression by acting on its promoter PMID: 21478910
    8. The early expression of OTX1 in proliferative cell layers of the human fetal brain supports the concept that this homeobox gene is important in neuronal cell development and differentiation. PMID: 20354145
    9. This study identifies OTX1 as a molecular marker for high-grade germinal center derived Non-Hodgkin Lymphoma PMID: 19893048
    10. Fine mapping of the chromosome 2p12-16 dyslexia susceptibility locus candidate gene PMID: 11901358
    11. OTR1, OTX2 and CRX act as positive modulators of the BEST1 promoter in the retinal pigment epithelium. PMID: 18849347
    12. In the human fetal eye, OTX1 expression was confined to anterior retina. PMID: 19414065

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Nucleus.
  • 蛋白家族:
    Paired homeobox family, Bicoid subfamily
  • 組織特異性:
    Expressed in brain. Detected in the anterior part of the neural fetal retina (at protein level).
  • 數(shù)據(jù)庫鏈接:

    HGNC: 8521

    OMIM: 600036

    KEGG: hsa:5013

    STRING: 9606.ENSP00000282549

    UniGene: Hs.734360



主站蜘蛛池模板: 国产精品亚韩精品无码a在线| 精品国产av无码一区二区三区| 色依依av在线| 小辣椒福利视频导航| 久久综合九色综合欧美就去吻| 女人裸露免费视频无遮挡网站 | 国产高清乱理伦片| 又色又爽又黄的美女裸体网站| 久久久久久久久久久综合日本| 国产美女自慰在线观看| 久久精品久久电影免费理论片 | 亚洲午夜久久久久久久久电影网 | 又大又粗又长的高潮视频| 久久九九久精品国产免费直播| 欧美肥胖老妇bbw| 国产人妻黑人一区二区三区 | 刺激性视频黄页| 久久久久国色av免费看图片| h人成在线看免费视频| 午夜福利92国语| 香港三级精品三级在线专区| 欧美性xxxxx极品少妇| 亚洲国产精品久久久天堂不卡海量 | 麻豆国产成人av在线播放欲色| 人妻丰满熟av无码区hd| 亚洲午夜福利在线观看| 亚洲精品国产av天美传媒| 国产99视频精品免费视频36| 天堂√在线中文最新版| 国产色婷婷亚洲99精品小说| 久久久综合亚洲色一区二区三区| 中文午夜乱理片无码| 国产亚洲精品国产福利你懂的| 久久九九有精品国产尤物| 99精品偷自拍| 久久97国产超碰青草| 中文字幕av无码人妻| 亚洲精品国产一区黑色丝袜| 欧美国产国产综合视频| 亚洲成色最大综合在线| 欧美日产欧美日产国产精品|