在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Homeobox protein MOX-1 (MEOX1)

  • 中文名稱:
    人MEOX1重組蛋白
  • 貨號:
    CSB-YP013695HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人MEOX1重組蛋白
  • 貨號:
    CSB-EP013695HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人MEOX1重組蛋白
  • 貨號:
    CSB-BP013695HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人MEOX1重組蛋白
  • 貨號:
    CSB-MP013695HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    MEOX1
  • Uniprot No.:
  • 別名:
    Homeobox protein MOX-1; MEOX1; MEOX1_HUMAN; Mesenchyme homeo box 1; Mesenchyme homeobox 1; MOX 1; MOX1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-254
  • 氨基酸序列
    MDPAASSCMR SLQPPAPVWG CLRNPHSEGN GASGLPHYPP TPFSFHQKPD FLATATAAYP DFSASCLAAT PHSLPQEEHI FTEQHPAFPQ SPNWHFPVSD ARRRPNSGPA GGSKEMGTSS LGLVDTTGGP GDDYGVLGST ANETEKKSSR RRKESSDNQE NRGKPEGSSK ARKERTAFTK EQLRELEAEF AHHNYLTRLR RYEIAVNLDL SERQVKVWFQ NRRMKWKRVK GGQPISPNGQ DPEDGDSTAS PSSE
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints. Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome.
  • 基因功能參考文獻:
    1. MEOX1 is a clinically relevant novel target in BCSCs and mesenchymal-like cancer cells in PTEN-deficient trastuzumab resistant breast cancer and may serve as target for future drug development. PMID: 27285982
    2. The G > A p.Q84X mutation in the MEOX1 is identified in Klippel-Feil syndrome. PMID: 24073994
    3. We describe a multiplex consanguineous family in which isolated KFS maps to a single 17q21.31 locus that harbors a homozygous frameshift deletion in MEOX1; this deletion results in complete instability of the transcript PMID: 23290072
    4. The results demonstrate that MEOX1 is a critical target gene and cofactor of PBX1 in ovarian cancers. PMID: 22567123
    5. No mutations were identified in the PAX1 and MEOX1 exons or flanking intronic sequences, excluding them as likely causative genes for diaphanospondylodysostosis PMID: 17764081

    顯示更多

    收起更多

  • 相關疾病:
    Klippel-Feil syndrome 2, autosomal recessive (KFS2)
  • 亞細胞定位:
    Nucleus. Cytoplasm.
  • 數據庫鏈接:

    HGNC: 7013

    OMIM: 214300

    KEGG: hsa:4222

    STRING: 9606.ENSP00000321684

    UniGene: Hs.438



主站蜘蛛池模板: 极品粉嫩嫩模大尺度无码视频| 国产一卡2卡3卡四卡精品app| 五月天精品视频在线观看| 性欧美熟妇videofreesex| 黑人糟蹋人妻hd中文字幕| 青青草国产线观看| 国产精品第一区揄拍无码| 美女视频黄频大全免费| 国产亚洲精品久久久久久大师 | 五月婷六月婷婷俺也去| 亚洲无线码中文字幕在线| 国产精品视频一区二区噜噜| 激情内射人妻1区2区3区| 免费精品国偷自产在线在线| 中文字幕大看蕉在线观看| 天天躁日日躁狠狠躁视频2021| 大香伊蕉国产av| 波多野结衣乱码中文字幕| 欧美35页视频在线观看| 亚洲中文字幕无码永久在线| 性色欲情网站iwww| 怀孕挺大肚子疯狂高潮av毛片| 99精品国产福久久久久久| 94久久国产乱子伦精品免费| 97se亚洲国产综合自在线尤物| 久久久国产精品无码一区二区| 国产欧美一区二区三区免费视频| 精品亚洲一区二区三区四区五区| 精品国产免费第一区二区三区| 怡红院成永久免费人视频新的| 一本色道久久综合无码人妻| 黑人玩弄人妻1区二区| 男女做爰猛烈啪啪吃奶伸舌头下载| 久久久国产乱子伦精品作者| 蜜臀av午夜一区二区三区| 久久婷婷国产剧情内射白浆| 国产无遮挡a片无码免费软件| 美女又黄又免费的视频| 国产精品午夜福利不卡| 精品国产卡一卡2卡3卡| 色国产精品一区在线观看|