在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Homeobox protein MOX-1 (MEOX1)

  • 中文名稱:
    人MEOX1重組蛋白
  • 貨號:
    CSB-EP013695HU
  • 規格:
    ¥1836
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    MEOX1
  • Uniprot No.:
  • 別名:
    Homeobox protein MOX-1; MEOX1; MEOX1_HUMAN; Mesenchyme homeo box 1; Mesenchyme homeobox 1; MOX 1; MOX1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length
  • 來源:
    E.coli
  • 分子量:
    55.0kDa
  • 表達區域:
    1-254aa
  • 氨基酸序列
    MDPAASSCMRSLQPPAPVWGCLRNPHSEGNGASGLPHYPPTPFSFHQKPDFLATATAAYPDFSASCLAATPHSLPQEEHIFTEQHPAFPQSPNWHFPVSDARRRPNSGPAGGSKEMGTSSLGLVDTTGGPGDDYGVLGSTANETEKKSSRRRKESSDNQENRGKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRVKGGQPISPNGQDPEDGDSTASPSSE
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal GST-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints. Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome.
  • 基因功能參考文獻:
    1. MEOX1 is a clinically relevant novel target in BCSCs and mesenchymal-like cancer cells in PTEN-deficient trastuzumab resistant breast cancer and may serve as target for future drug development. PMID: 27285982
    2. The G > A p.Q84X mutation in the MEOX1 is identified in Klippel-Feil syndrome. PMID: 24073994
    3. We describe a multiplex consanguineous family in which isolated KFS maps to a single 17q21.31 locus that harbors a homozygous frameshift deletion in MEOX1; this deletion results in complete instability of the transcript PMID: 23290072
    4. The results demonstrate that MEOX1 is a critical target gene and cofactor of PBX1 in ovarian cancers. PMID: 22567123
    5. No mutations were identified in the PAX1 and MEOX1 exons or flanking intronic sequences, excluding them as likely causative genes for diaphanospondylodysostosis PMID: 17764081

    顯示更多

    收起更多

  • 相關疾病:
    Klippel-Feil syndrome 2, autosomal recessive (KFS2)
  • 亞細胞定位:
    Nucleus. Cytoplasm.
  • 數據庫鏈接:

    HGNC: 7013

    OMIM: 214300

    KEGG: hsa:4222

    STRING: 9606.ENSP00000321684

    UniGene: Hs.438



主站蜘蛛池模板: 国产av久久人人澡人人爱| 国产一性一交一伦一a片| 麻豆乱码国产一区二区三区| 免费无码不卡中文字幕在线| 欧美人与动牲交app视频| 中文字字幕在线成人av电影| 亚洲人成网站18禁止无码| 国产亚洲精品久久久久久打不开| 久久国产精品免费一区| 亚洲愉拍自拍另类天堂| 国产97色在线 | 亚洲| 日本三级理论久久人妻电影| 欧美午夜片欧美片在线观看| 内射女校花一区二区三区| 精品久久久久久人妻无码中文字幕| 骚虎视频在线观看| 99久久国产亚洲高清观看| 精品国模一区二区三区| 久久亚洲私人国产精品| 人人妻人人澡人人爽人人精品97| 97人人超碰国产精品最新| 亚洲欧洲中文日韩久久av乱码| 亚洲成a人片在线观看高清| 又黄又粗又爽免费观看| 国产精品成人午夜久久| 精品国产三级在线观看| 精品国产杨幂在线观看| 欧美精品18videosex性欧| 在线看亚洲十八禁网站| 天堂在线中文网www| 午夜爱爱免费视频体验区| 日本另类αv欧美另类aⅴ| 中文字幕乱码人妻一区二区三区| 亚洲香蕉aⅴ视频在线播放| 日韩精品电影综合区亚洲| 久久国产福利国产秒拍| 夜夜躁狠狠躁日日躁孕妇| 伊人久久大香线蕉av仙人| 天天鲁一鲁摸一摸爽一爽| 亚洲乱亚洲乱少妇无码| 色哟哟免费视频播放网站|