在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Histone H4 transcription factor (HINFP)

  • 中文名稱:
    人HINFP重組蛋白
  • 貨號:
    CSB-YP010361HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人HINFP重組蛋白
  • 貨號:
    CSB-EP010361HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人HINFP重組蛋白
  • 貨號:
    CSB-EP010361HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人HINFP重組蛋白
  • 貨號:
    CSB-BP010361HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人HINFP重組蛋白
  • 貨號:
    CSB-MP010361HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    HINFP
  • Uniprot No.:
  • 別名:
    DKFZp434F162; HiNF-P; HINFP; HINFP_HUMAN; Histone H4 gene specific protein HiNF P; Histone H4 transcription factor; Histone nuclear factor P; MBD2 (methyl-CpG-binding protein)-interacting zinc finger protein; MBD2 interacting zinc finger 1; MBD2 interacting zinc finger protein; MBD2-interacting zinc finger protein; Methyl CpG binding protein 2 interacting zinc finger protein; Methyl-CpG-binding protein 2-interacting zinc finger protein; MIZF; ZNF743
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-517
  • 氨基酸序列
    MPPPGKVPRK ENLWLQCEWG SCSFVCSTME KFFEHVTQHL QQHLHGSGEE EEEEEEDDPL EEEFSCLWQE CGFCSLDSSA DLIRHVYFHC YHTKLKQWGL QALQSQADLG PCILDFQSRN VIPDIPDHFL CLWEHCENSF DNPEWFYRHV EAHSLCCEYE AVGKDNPVVL CGWKGCTCTF KDRSKLREHL RSHTQEKVVA CPTCGGMFAN NTKFLDHIRR QTSLDQQHFQ CSHCSKRFAT ERLLRDHMRN HVNHYKCPLC DMTCPLPSSL RNHMRFRHSE DRPFKCDCCD YSCKNLIDLQ KHLDTHSEEP AYRCDFENCT FSARSLCSIK SHYRKVHEGD SEPRYKCHVC DKCFTRGNNL TVHLRKKHQF KWPSGHPRFR YKEHEDGYMR LQLVRYESVE LTQQLLRQPQ EGSGLGTSLN ESSLQGIILE TVPGEPGRKE EEEEGKGSEG TALSASQDNP SSVIHVVNQT NAQGQQEIVY YVLSEAPGEP PPAPEPPSGG IMEKLQGIAE EPEIQMV
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Transcriptional repressor that binds to the consensus sequence 5'-CGGACGTT-3' and to the RB1 promoter. Transcriptional activator that promotes histone H4 gene transcription at the G1/S phase transition in conjunction with NPAT. Also activates transcription of the ATM and PRKDC genes. Autoregulates its expression by associating with its own promoter.
  • 基因功能參考文獻:
    1. purified and functionally characterized the critical transcription factor HiNF-P, which is required for E2F-independent activation of the histone H4 multigene family PMID: 14585971
    2. These results suggest that transcriptional repression of Rb by MIZF could be one of the critical determinants in myogenic differentiation. PMID: 15541338
    3. HiNF-P interacts directly with p220(NPAT) to coactivate histone genes during S phase. PMID: 15988025
    4. the transcriptional silencing of the 14-3-3sigma gene is caused by promoter CpG island methylation associated with MBD2, which may play an important role in prostate cancer progression during the invasive and metastatic stages of the disease PMID: 16786000
    5. These results suggest that RFP is a mediator connecting several MBD proteins and allowing the formation of a more potent transcriptional repressor complex. PMID: 17049487
    6. HiNF-P is a bifunctional regulator of cell cycle controlled histone H4 gene transcription. PMID: 17163457
    7. HiNF-P-dependent stabilization of p220NPAT reinforces signaling through the cyclin E/CDK2/p220NPAT pathway and contributes to coordinate control of histone gene expression. PMID: 17176114
    8. HiNF-P/P220NPAT regulates expression of nonhistone targets that influence competency for cell cycle progression. PMID: 17974976
    9. a novel HiNF-P-specific conserved region represents a DNA-binding determinant that plays a role in mediating histone gene expression during the cell cycle and defines HiNF-P as a cell cycle regulatory member of the zinc finger transcription factor family PMID: 18850719
    10. Results suggest that cyclin-dependent kinase inhibitors selectively control stimulation of the histone H4 gene promoter by the p220(NPAT)/HiNF-P complex. PMID: 19170105

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Note=Associated with discrete nuclear foci.
  • 組織特異性:
    Ubiquitous. Highly expressed in brain, heart, skeletal muscle, spleen, kidney, small intestine, placenta and liver.
  • 數據庫鏈接:

    HGNC: 17850

    OMIM: 607099

    KEGG: hsa:25988

    STRING: 9606.ENSP00000318085

    UniGene: Hs.504091



主站蜘蛛池模板: 国产午夜精华无码网站| 中文字幕av在线一二三区| 亚洲最大的imax影院 | 久久久一本精品99久久精品66直播| 99精品国产一区二区三区a片| 亚洲中文无码av在线| 337p西西人体大胆瓣开下部| 99视频有精品视频高清| 亚洲精品国产高清一线久久| 国产亚洲精久久久久久无码苍井空| 亚洲中文字幕无码av永久| 五月丁香啪啪激情综合色九色 | 中文乱码字幕高清一区二区| 手机真实国产乱子伦对白视频| 人人插人人插人人爽| 高清精品一区二区三区| 亚洲日本中文字幕乱码在线| 亚洲成av人片在线观看无| 99久久国产露脸国语对白 | 日韩av一国产av一中文字慕| 四库影院永久四虎精品国产| 蜜臀av在线播放一区二区三区| 中国熟妇浓毛hdsex| 动漫av纯肉无码免费播放| 亚洲精品黑牛一区二区三区| 全黄h全肉边做边吃奶视频| 国产蜜芽尤物在线一区| 69国产精品久久久久久人妻| 老熟女乱子伦| 在线视频精品免费观看10| 亚洲中文字幕乱码熟女在线| 色欲香天天天综合网站| 日本亲近相奷中文字幕| 国产麻豆精品福利在线| 少妇一晚三次一区二区三区| 日本伊人色综合网| 窝窝午夜看片成人精品| 在线精品无码字幕无码av| 国产精品夜间视频香蕉| 久久久久无码精品国产人妻无码| 一边吃奶一边添p好爽高清视频|