在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

HINFP Antibody, Biotin conjugated

  • 中文名稱:
    HINFP兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA010361LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) HINFP Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    HINFP
  • 別名:
    DKFZp434F162 antibody; HiNF-P antibody; HINFP antibody; HINFP_HUMAN antibody; Histone H4 gene specific protein HiNF P antibody; Histone H4 transcription factor antibody; Histone nuclear factor P antibody; MBD2 (methyl-CpG-binding protein)-interacting zinc finger protein antibody; MBD2 interacting zinc finger 1 antibody; MBD2 interacting zinc finger protein antibody; MBD2-interacting zinc finger protein antibody; Methyl CpG binding protein 2 interacting zinc finger protein antibody; Methyl-CpG-binding protein 2-interacting zinc finger protein antibody; MIZF antibody; ZNF743 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Histone H4 transcription factor protein (370-515AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Transcriptional repressor that binds to the consensus sequence 5'-CGGACGTT-3' and to the RB1 promoter. Transcriptional activator that promotes histone H4 gene transcription at the G1/S phase transition in conjunction with NPAT. Also activates transcription of the ATM and PRKDC genes. Autoregulates its expression by associating with its own promoter.
  • 基因功能參考文獻:
    1. purified and functionally characterized the critical transcription factor HiNF-P, which is required for E2F-independent activation of the histone H4 multigene family PMID: 14585971
    2. These results suggest that transcriptional repression of Rb by MIZF could be one of the critical determinants in myogenic differentiation. PMID: 15541338
    3. HiNF-P interacts directly with p220(NPAT) to coactivate histone genes during S phase. PMID: 15988025
    4. the transcriptional silencing of the 14-3-3sigma gene is caused by promoter CpG island methylation associated with MBD2, which may play an important role in prostate cancer progression during the invasive and metastatic stages of the disease PMID: 16786000
    5. These results suggest that RFP is a mediator connecting several MBD proteins and allowing the formation of a more potent transcriptional repressor complex. PMID: 17049487
    6. HiNF-P is a bifunctional regulator of cell cycle controlled histone H4 gene transcription. PMID: 17163457
    7. HiNF-P-dependent stabilization of p220NPAT reinforces signaling through the cyclin E/CDK2/p220NPAT pathway and contributes to coordinate control of histone gene expression. PMID: 17176114
    8. HiNF-P/P220NPAT regulates expression of nonhistone targets that influence competency for cell cycle progression. PMID: 17974976
    9. a novel HiNF-P-specific conserved region represents a DNA-binding determinant that plays a role in mediating histone gene expression during the cell cycle and defines HiNF-P as a cell cycle regulatory member of the zinc finger transcription factor family PMID: 18850719
    10. Results suggest that cyclin-dependent kinase inhibitors selectively control stimulation of the histone H4 gene promoter by the p220(NPAT)/HiNF-P complex. PMID: 19170105

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Note=Associated with discrete nuclear foci.
  • 組織特異性:
    Ubiquitous. Highly expressed in brain, heart, skeletal muscle, spleen, kidney, small intestine, placenta and liver.
  • 數據庫鏈接:

    HGNC: 17850

    OMIM: 607099

    KEGG: hsa:25988

    STRING: 9606.ENSP00000318085

    UniGene: Hs.504091



主站蜘蛛池模板: 小12箩利洗澡无码视频网站| 成人免费无码大片a毛片| 欧美 变态 另类 人妖| 无码人妻啪啪一区二区| 免费视频爱爱太爽了| 亚洲精品制服丝袜四区| 亚洲成av人无码中文字幕| 在线精品国产大象香蕉网| 漂亮人妻被中出中文字幕| 国产精品无码免费播放| 骚片av蜜桃精品一区| 亚洲 日本 欧美 中文字幕| 成人免费无码大片a毛片户外| 国产一区二区三区不卡在线观看| 吸咬奶头狂揉60分钟视频| 久久久老熟女一区二区三区| 亚洲另类自拍丝袜第五页| 护士av无码在线观看| 麻豆果冻传媒2021精品传媒一区 | 亚洲熟妇丰满xxxxx| 亚洲日韩国产精品第一页一区| 狠狠躁夜夜躁人人爽超碰97香蕉 | 久久国产人妻一区二区免费| 玩超薄丝袜人妻的经历| 久久久亚洲欧洲日产国产成人无码 | 亚洲最大的熟女水蜜桃av网站| 久久久精品人妻一区二区三区蜜桃 | 天干天干天啪啪夜爽爽av| 偷偷要色偷偷中文无码| 99久久国产综合精品女图图等你| 中文国产成人精品久久app| 成人午夜高潮免费视频| 无码人妻一区二区三区免费视频| 国产a线视频播放| 三级网站视频在在线播放| 久久综合久久久久88| www亚洲精品久久久| 欧美性生交xxxxx无码久久久| 亚洲日本一区二区三区在线| 俄罗斯丰满熟妇hd| 中文精品一卡2卡3卡4卡国色|