在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Hemoglobin subunit delta (HBD)

In Stock
  • 中文名稱:
    人HBD重組蛋白
  • 貨號:
    CSB-EP010152HU
  • 規格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    Delta-globin Hemoglobin delta chain
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.coli
  • 分子量:
    47.5 kDa
  • 表達區域:
    2-147aa
  • 氨基酸序列
    VHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFGKEFTPQMQAAYQKVVAGVANALAHKYH
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-GST-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Involved in oxygen transport from the lung to the various peripheral tissues.
  • 基因功能參考文獻:
    1. Blood donor homozygous for Hb D Los Angeles. PMID: 25217459
    2. The expression of the activated delta-globin gene in a beta-thalassemia mice model greatly improves the phenotype, validating the delta-globin chain as a therapeutic target for beta-hemoglobinopathies. PMID: 23872310
    3. Data indicate that a delta-globin mutation was suspected in both patients. PMID: 23806011
    4. Twenty-one different mutations were detected, and of these 12 have not been previously described. PMID: 23215833
    5. A functional promoter polymorphism of the delta-globin gene is a specific marker of the Arab-Indian haplotype PMID: 22641479
    6. This report describes a novel missense mutation in delta-globin (HBD: c.323G>A, Gly > Asp) in an Indian family with heterozygous beta-thalassemia with normal HbA(2) levels. PMID: 22477537
    7. The 5' breakapoint of the (deltabeta)(0) thalassemia deletion in a compound heterozygote was located in the second intron of the delta globin gene. PMID: 11860449
    8. Hb A2-Monreale [delta146(HC3)His-->Arg]is a novel delta chain variant. PMID: 11939506
    9. alternate mRNA species in adult erythroid cells; mRNA encodes an additional 145 nt in the upstream untranslated region, suggesting an alternative site of transcriptional initiation and transcription through the previously defined promoter PMID: 15234005
    10. The atomic coordinates of the delta-chain of hemoglobin A2 (R2 state) are used to model the structure of hemoglobin homotetramer delta 4, which occurs in rare hemoglobin H disease. PMID: 15449937
    11. Deletion pf this geneis a common, and possibly the predominant beta-thalassemia mutation of the Austroasiatic Lao Theung population. PMID: 15757827
    12. characterization of the delta-globin gene alleles and of RFLP-haplotypes, SNPs and one microsatellite associated with them in 231 carriers originating principally from East Sicily; Seventeen alleles were identified, of which five were new PMID: 18221842
    13. Borderline HbA(2) is not a rare event in a population with a high prevalence of beta-thalassemia carriers PMID: 18603555
    14. Unusually low levels of HBA2 in a compound heterozygote can be explained from the functional inhibition of the HBD gene, in cis to the HBG1 gene, bearing the nd-HPFH mutation. PMID: 18615450
    15. Hb A2 IVS-I-5 (G > C) beta-thalassemia mutation phenotype in 289 carriers was reported. PMID: 18932068

    顯示更多

    收起更多

  • 蛋白家族:
    Globin family
  • 組織特異性:
    Red blood cells.
  • 數據庫鏈接:

    HGNC: 4829

    OMIM: 142000

    KEGG: hsa:3045

    STRING: 9606.ENSP00000369654

    UniGene: Hs.699280



主站蜘蛛池模板: 极品少妇xxxx精品少妇偷拍| 97国产在线看片免费人成视频| 强奷妇系列中文字幕| 男女啪动最猛动态图| 国产另类ts人妖一区二区| 尤物国产在线精品福利三区| 99精品国产福利一区二区| 免费网站观看www在线观看| 天堂а√在线中文在线| 免费国产va在线观看| 香港三日本8a三级少妇三级99| 亚洲精品国产精华液| 久久婷婷久久一区二区三区| 精品一卡2卡三卡4卡乱码精品视频| 天堂中文官网在线| 午夜无码一区二区三区在线观看| 午夜私人成年影院| 亚洲线精品一区二区三八戒| 亚洲人成色77777| 欧美深性狂猛ⅹxxx深喉| 无码一区二区三区老色鬼| 精品无码国产自产在线观看水浒传 | 少妇人妻挤奶水中文视频毛片| 欧美另类人妖| 亚洲国产成人综合精品| 尤物193在线人妻精品免费| 亚洲自偷自拍另类12p| 亚洲国产精品第一区二区| www国产内插视频| 老汉色老汉首页a亚洲| 日韩精品射精管理在线观看| 放荡的少妇2欧美版| 亚洲精品www久久久久久| 国产高潮又爽又刺激的视频| 免费看成人毛片无码视频| 看免费真人视频网站| 久久精品女人的天堂av| 中文字幕一区日韩精品| 成人动漫综合网| 色先锋资源久久综合5566| 熟女乱牛牛视频在线观看|