在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Hemoglobin subunit delta (HBD)

  • 中文名稱:
    人HBD重組蛋白
  • 貨號:
    CSB-YP010152HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人HBD重組蛋白
  • 貨號:
    CSB-EP010152HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人HBD重組蛋白
  • 貨號:
    CSB-BP010152HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人HBD重組蛋白
  • 貨號:
    CSB-MP010152HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Delta-globin; HBD; HBD_HUMAN; Hemoglobin delta chain; Hemoglobin subunit delta
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區(qū)域:
    2-147
  • 氨基酸序列
    VHLTPEEKT AVNALWGKVN VDAVGGEALG RLLVVYPWTQ RFFESFGDLS SPDAVMGNPK VKAHGKKVLG AFSDGLAHLD NLKGTFSQLS ELHCDKLHVD PENFRLLGNV LVCVLARNFG KEFTPQMQAA YQKVVAGVAN ALAHKYH
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Involved in oxygen transport from the lung to the various peripheral tissues.
  • 基因功能參考文獻:
    1. Blood donor homozygous for Hb D Los Angeles. PMID: 25217459
    2. The expression of the activated delta-globin gene in a beta-thalassemia mice model greatly improves the phenotype, validating the delta-globin chain as a therapeutic target for beta-hemoglobinopathies. PMID: 23872310
    3. Data indicate that a delta-globin mutation was suspected in both patients. PMID: 23806011
    4. Twenty-one different mutations were detected, and of these 12 have not been previously described. PMID: 23215833
    5. A functional promoter polymorphism of the delta-globin gene is a specific marker of the Arab-Indian haplotype PMID: 22641479
    6. This report describes a novel missense mutation in delta-globin (HBD: c.323G>A, Gly > Asp) in an Indian family with heterozygous beta-thalassemia with normal HbA(2) levels. PMID: 22477537
    7. The 5' breakapoint of the (deltabeta)(0) thalassemia deletion in a compound heterozygote was located in the second intron of the delta globin gene. PMID: 11860449
    8. Hb A2-Monreale [delta146(HC3)His-->Arg]is a novel delta chain variant. PMID: 11939506
    9. alternate mRNA species in adult erythroid cells; mRNA encodes an additional 145 nt in the upstream untranslated region, suggesting an alternative site of transcriptional initiation and transcription through the previously defined promoter PMID: 15234005
    10. The atomic coordinates of the delta-chain of hemoglobin A2 (R2 state) are used to model the structure of hemoglobin homotetramer delta 4, which occurs in rare hemoglobin H disease. PMID: 15449937
    11. Deletion pf this geneis a common, and possibly the predominant beta-thalassemia mutation of the Austroasiatic Lao Theung population. PMID: 15757827
    12. characterization of the delta-globin gene alleles and of RFLP-haplotypes, SNPs and one microsatellite associated with them in 231 carriers originating principally from East Sicily; Seventeen alleles were identified, of which five were new PMID: 18221842
    13. Borderline HbA(2) is not a rare event in a population with a high prevalence of beta-thalassemia carriers PMID: 18603555
    14. Unusually low levels of HBA2 in a compound heterozygote can be explained from the functional inhibition of the HBD gene, in cis to the HBG1 gene, bearing the nd-HPFH mutation. PMID: 18615450
    15. Hb A2 IVS-I-5 (G > C) beta-thalassemia mutation phenotype in 289 carriers was reported. PMID: 18932068

    顯示更多

    收起更多

  • 蛋白家族:
    Globin family
  • 組織特異性:
    Red blood cells.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 4829

    OMIM: 142000

    KEGG: hsa:3045

    STRING: 9606.ENSP00000369654

    UniGene: Hs.699280



主站蜘蛛池模板: 午夜福利啪啪片| 啪啪后入内射日韩| 一本无码中文字幕在线观| 自拍偷在线精品自拍偷免费 | 99国产精品欧美一区二区三区 | 天堂8在线天堂资源bt| 国产999精品久久久久久| 国产偷人妻精品一区| 久久香综合精品久久伊人| 国产成人精品精品日本亚洲| 朝鲜女人大白屁股ass孕交| 18精品久久久无码午夜福利| 国产精品久久综合免费| 无码免费中文字幕视频| 亚洲风情亚aⅴ在线发布| 久久综合久久鬼色| 老司机在线精品视频网站| 亚洲熟妇av一区| 国产天美传媒性色av| 欧美巨大xxxx做受高清| 1313午夜精品理论片| 日日夜夜撸啊撸| 久久久亚洲欧洲日产国码农村 | 小泽玛莉亚一区二区视频在线| 中文日产乱幕九区无线码| 人妻无码中文专区久久五月婷| 人妻色综合网站| 久久精品女人的天堂av| 自偷自拍亚洲综合精品麻豆| 久久婷婷成人综合色综合| 性生交大片免费看女人按摩摩| 国产99青草视频在线播放视 | 午夜嘿嘿嘿在线观看| 国产又色又爽又黄又免费| 免费观看18禁无遮挡真人网站| 久久婷婷综合缴情亚洲狠狠_| 日本大香伊一区二区三区| 久久精品亚洲日本波多野结衣 | 日韩av高清无码| 国产成久久免费精品av片| 少妇仑乱a毛片|