在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human HERV-H LTR-associating protein 2 (HHLA2), partial

  • 中文名稱:
    人HHLA2重組蛋白
  • 貨號:
    CSB-YP891555HU1
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人HHLA2重組蛋白
  • 貨號:
    CSB-EP891555HU1
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人HHLA2重組蛋白
  • 貨號:
    CSB-EP891555HU1-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人HHLA2重組蛋白
  • 貨號:
    CSB-BP891555HU1
  • 規格:
  • 來源:
    Baculovirus
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    HHLA2; HERV-H LTR-associating protein 2; Human endogenous retrovirus-H long terminal repeat-associating protein 2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
  • 基因功能參考文獻:
    1. HHLA2 protein expression was evaluated in primary tumor specimens and metastatic disease using an osteosarcoma tumor microarray. HHLA2 was expressed in almost all metastatic disease specimens and was more prevalent than in primary specimens without known metastases. PMID: 27531281
    2. HHLA2 was not detected in most of normal lung tissue but expressed in 66% of NSCLC across different subtypes. In particular, EGFR-mutated NSCLC was significantly associated with higher tumor HHLA2 expression in both discovery and validation lung cancer cohorts. HHLA2 is widely expressed in NSCLC and is associated with EGFR mutation and high TILs in lung adenocarcinoma. PMID: 27553831
    3. Low B7-H5 expression is associated with pancreatic adenocarcinomas. PMID: 25519928
    4. The HHLA2 pathway represents a novel immunosuppressive mechanism within the tumor microenvironment. PMID: 25549724
    5. B7 homologue 5 (B7-H5), was identified as a specific ligand for CD28H PMID: 23784006
    6. Data indicate that HHLA2 protein was predominantly found on cell membranes with some in the cytoplasm. PMID: 23716685

    顯示更多

    收起更多

  • 亞細胞定位:
    Membrane; Single-pass type I membrane protein.
  • 組織特異性:
    Expressed at high levels in colon, kidney, testis, lung and pancreas, and at lower levels in small intestine, liver and skeletal muscle. In immune cells, highly expressed in B-cells, dendritic cells and macrophages. Not detected in T-cells.
  • 數據庫鏈接:

    HGNC: 4905

    OMIM: 604371

    KEGG: hsa:11148

    STRING: 9606.ENSP00000350402

    UniGene: Hs.225968



主站蜘蛛池模板: 国产萌白酱喷水视频在线观看 | 欧美中文字幕无线码视频| 免费无码久久成人网站入口| 久碰人妻人妻人妻人妻人掠| 精品久久久久久中文字幕| 无套熟女av呻吟在线观看| 国精产品69永久中国有限| 一个添下面两个吃奶把腿扒开 | 久久久久国产一区二区| 国产无限次数成版人视频在线| 人妻系列影片无码专区| 久久久久久午夜成人影院| 婷婷久久综合九色综合| 在线看片免费人成视频在线影院| 精品国内综合一区二区| 色婷婷亚洲一区二区综合 | 久久中文字幕人妻熟av女蜜柚m| 亚洲乱码无码永久不卡在线 | 亚洲色自偷自拍另类小说| 亚洲在av极品无码| 欧美熟妇色ⅹxxx欧美妇| 成 人 色 网 站免费观看| 人妻无码一区二区三区tv| 亚洲一区精品无码色成人| 亚洲综合av一区二区三区| 老湿机69福利区无码| 黑人巨大videos精品| 国产成人久久av免费| 污污污www精品国产网站| 亚洲v国产v欧美v久久久久久| 99精品国产丝袜在线拍国语| 日产精品久久久久久久蜜臀| 丰满人妻熟妇乱又伦精品视| 亚洲国产人成自精在线尤物| 国产又黄又湿无遮挡免费视频| 国产奶头好大揉着好爽视频| 国产精品人人妻人人爽| 亚洲精品成人福利网站| 日日夜夜撸啊撸| 国产欧美精品一区二区三区-老狼| 亚洲美女视频高清在线看|