在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. HHLA2 Antibody, FITC conjugated

HHLA2 Antibody, FITC conjugated

  • 中文名稱：
    HHLA2兔多克隆抗體, FITC偶聯(lián)
  • 貨號(hào)：
    CSB-PA891555LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) HHLA2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    HHLA2; HERV-H LTR-associating protein 2; Human endogenous retrovirus-H long terminal repeat-associating protein 2
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human HERV-H LTR-associating protein 2 protein (172-258AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
  • 基因功能參考文獻(xiàn)：
    1. HHLA2 protein expression was evaluated in primary tumor specimens and metastatic disease using an osteosarcoma tumor microarray. HHLA2 was expressed in almost all metastatic disease specimens and was more prevalent than in primary specimens without known metastases. PMID: 27531281
    2. HHLA2 was not detected in most of normal lung tissue but expressed in 66% of NSCLC across different subtypes. In particular, EGFR-mutated NSCLC was significantly associated with higher tumor HHLA2 expression in both discovery and validation lung cancer cohorts. HHLA2 is widely expressed in NSCLC and is associated with EGFR mutation and high TILs in lung adenocarcinoma. PMID: 27553831
    3. Low B7-H5 expression is associated with pancreatic adenocarcinomas. PMID: 25519928
    4. The HHLA2 pathway represents a novel immunosuppressive mechanism within the tumor microenvironment. PMID: 25549724
    5. B7 homologue 5 (B7-H5), was identified as a specific ligand for CD28H PMID: 23784006
    6. Data indicate that HHLA2 protein was predominantly found on cell membranes with some in the cytoplasm. PMID: 23716685

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Membrane; Single-pass type I membrane protein.
  • 組織特異性：
    Expressed at high levels in colon, kidney, testis, lung and pancreas, and at lower levels in small intestine, liver and skeletal muscle. In immune cells, highly expressed in B-cells, dendritic cells and macrophages. Not detected in T-cells.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 4905

    OMIM: 604371

    KEGG: hsa:11148

    STRING: 9606.ENSP00000350402

    UniGene: Hs.225968



主站蜘蛛池模板： 国产啪精品视频网站免| 国产xxxx做受性欧美88| 亚洲aⅴ在线无码天堂777| 18禁超污无遮挡无码网址| 欧美精品a∨在线观看| av人摸人人人澡人人超碰下载| 在线观看特色大片免费网站| √天堂资源地址中文在线| 色噜噜狠狼综合在线| 白嫩无码人妻丰满熟妇啪啪区百度| 欧美成人aaaa免费全部观看 | 国产精品卡一卡2卡3卡4| 久久亚洲国产成人精品无码区 | 亚洲国产美女精品久久久久∴| 夜夜春亚洲嫩草影院| 最近中文字幕mv在线视频看 | 18禁男女无遮挡啪啪网站| 国产男女猛烈无遮挡免费视频网站| 色翁荡熄又大又硬又粗又视频| av无码东京热亚洲男人的天堂| 无码人妻精品一区二区三区免费 | 日本乱偷人妻中文字幕| 欧美成人午夜免费全部完| 精品婷婷色一区二区三区| 久久996re热这里有精品| 午夜精品久久久久久| 欧美疯狂性受xxxxx喷水| 日本理论片午午伦夜理片2021| 国产 日韩 中文字幕 制服| 国产精品v片在线观看不卡 | 西西人体大胆午夜视频| 国产麻豆放荡av剧情演绎| 欧洲女人牲交性开放视频| 人妻av无码专区久久| 国产精品xxx在线| 麻豆国产在线精品国偷产拍| 成熟老妇女毛茸茸的做性| 免费三级网站| 国产欧美二区综合| 国产999久久高清免费观看| 熟女少妇人妻中文字幕|