在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. HHLA2 Antibody, FITC conjugated

HHLA2 Antibody, FITC conjugated

  • 中文名稱：
    HHLA2兔多克隆抗體, FITC偶聯(lián)
  • 貨號(hào)：
    CSB-PA891555LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) HHLA2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    HHLA2; HERV-H LTR-associating protein 2; Human endogenous retrovirus-H long terminal repeat-associating protein 2
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human HERV-H LTR-associating protein 2 protein (172-258AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
  • 基因功能參考文獻(xiàn)：
    1. HHLA2 protein expression was evaluated in primary tumor specimens and metastatic disease using an osteosarcoma tumor microarray. HHLA2 was expressed in almost all metastatic disease specimens and was more prevalent than in primary specimens without known metastases. PMID: 27531281
    2. HHLA2 was not detected in most of normal lung tissue but expressed in 66% of NSCLC across different subtypes. In particular, EGFR-mutated NSCLC was significantly associated with higher tumor HHLA2 expression in both discovery and validation lung cancer cohorts. HHLA2 is widely expressed in NSCLC and is associated with EGFR mutation and high TILs in lung adenocarcinoma. PMID: 27553831
    3. Low B7-H5 expression is associated with pancreatic adenocarcinomas. PMID: 25519928
    4. The HHLA2 pathway represents a novel immunosuppressive mechanism within the tumor microenvironment. PMID: 25549724
    5. B7 homologue 5 (B7-H5), was identified as a specific ligand for CD28H PMID: 23784006
    6. Data indicate that HHLA2 protein was predominantly found on cell membranes with some in the cytoplasm. PMID: 23716685

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Membrane; Single-pass type I membrane protein.
  • 組織特異性：
    Expressed at high levels in colon, kidney, testis, lung and pancreas, and at lower levels in small intestine, liver and skeletal muscle. In immune cells, highly expressed in B-cells, dendritic cells and macrophages. Not detected in T-cells.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 4905

    OMIM: 604371

    KEGG: hsa:11148

    STRING: 9606.ENSP00000350402

    UniGene: Hs.225968



主站蜘蛛池模板： 国产精品无码久久av| 国产av天堂亚洲国产av麻豆| 粉嫩小泬无遮挡久久久久久| 特级av毛片免费观看| 欧美xxxx狂喷水| 精品四虎国产在免费观看| 日本丶国产丶欧美色综合| 极品少妇被啪到呻吟喷水| 午夜视频久久久久一区| 国产成人a∨麻豆精品| 国产三级a三级三级| 亚洲综合无码久久精品综合| 在线观看片免费人成视频播放| 亚洲精品四区麻豆文化传媒| 开心婷婷五月激情综合社区| 国产成人无码免费看片软件| 日本丰满熟妇videossex| 夜夜欢性恔真人免费视频| 黑人玩弄人妻中文在线| 国模无码一区二区三区| 日本两人免费观看的视频| 午夜大片男女免费观看爽爽爽尤物| 99精品国产成人一区二区| 国产免费一区二区三区免费视频| 99在线 | 亚洲| 日韩一区二区三区无码人妻视频| 一个人看的www免费视频在线观看| 国产又色又爽又黄的在线观看视频 | 无码中文字幕日韩专区视频 | 2021国产精品成人免费视频| 国产精品v片在线观看不卡| 国产福利视频一区二区| 在线视频 亚太 国产 欧美 一区二区 | 国产真实的和子乱拍在线观看| 欧美在线 | 亚洲| 看成年全黄大色黄大片| 亚洲精品久久午夜麻豆| 中文字幕人成乱码熟女免费| 日本三级香港三级人妇三| 色琪琪av中文字幕一区二区| av在线播放日韩亚洲欧|