在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Golgi reassembly-stacking protein 2 (GORASP2)

  • 中文名稱:
    人GORASP2重組蛋白
  • 貨號:
    CSB-YP880999HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人GORASP2重組蛋白
  • 貨號:
    CSB-EP880999HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人GORASP2重組蛋白
  • 貨號:
    CSB-EP880999HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人GORASP2重組蛋白
  • 貨號:
    CSB-BP880999HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人GORASP2重組蛋白
  • 貨號:
    CSB-MP880999HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    GORASP2
  • Uniprot No.:
  • 別名:
    AW552058; DKFZp434D156; FLJ13139; Golgi phosphoprotein 6; Golgi reassembly stacking protein 2; Golgi reassembly stacking protein 2; 55kDa; Golgi reassembly stacking protein of 55 kDa; Golgi reassembly-stacking protein 2; Golgi reassembly-stacking protein of 55 kDa; GOLPH2; GOLPH6; GORASP2; GORS2_HUMAN; GRASP55; GRS2; p59; RP23-428O15.1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    2-452
  • 氨基酸序列
    GSSQSVEIP GGGTEGYHVL RVQENSPGHR AGLEPFFDFI VSINGSRLNK DNDTLKDLLK ANVEKPVKML IYSSKTLELR ETSVTPSNLW GGQGLLGVSI RFCSFDGANE NVWHVLEVES NSPAALAGLR PHSDYIIGAD TVMNESEDLF SLIETHEAKP LKLYVYNTDT DNCREVIITP NSAWGGEGSL GCGIGYGYLH RIPTRPFEEG KKISLPGQMA GTPITPLKDG FTEVQLSSVN PPSLSPPGTT GIEQSLTGLS ISSTPPAVSS VLSTGVPTVP LLPPQVNQSL TSVPPMNPAT TLPGLMPLPA GLPNLPNLNL NLPAPHIMPG VGLPELVNPG LPPLPSMPPR NLPGIAPLPL PSEFLPSFPL VPESSSAASS GELLSSLPPT SNAPSDPATT TAKADAASSL TVDVTPPTAK APTTVEDRVG DSTPVSEKPV SAAVDANASE SP
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Plays a role in the assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after breakdown during mitosis and meiosis. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA. Required for normal acrosome formation during spermiogenesis and normal male fertility, probably by promoting colocalization of JAM2 and JAM3 at contact sites between germ cells and Sertoli cells. Mediates ER stress-induced unconventional (ER/Golgi-independent) trafficking of core-glycosylated CFTR to cell membrane.
  • 基因功能參考文獻:
    1. Results demonstrate a critical role for GRASP55 and GRASP65 in maintaining the stacked structure of the Golgi, which is required for accurate posttranslational modifications in the Golgi. Additionally, the GRASP knockout cell lines developed in this study will be useful tools for studying the role of GRASP proteins in other important cellular processes. PMID: 28814501
    2. binding site at the cleft between the PDZ1 and PDZ2 domains of GRASP65 is dominated by hydrophobic interactions with GM130 that are not observed in the GRASP55-Golgin45 complex PMID: 28049725
    3. GRASP55 interacts with CD83 shortly after induction of dendritic cells maturation. PMID: 25701785
    4. Cisternal-specific functions of GRASP65 and GRASP55 in continuity, compartmentalization, and function of the Golgi ribbon. PMID: 24227884
    5. propose that GRASP55/65 are negative regulators of exocytic transport and that this slowdown helps to ensure more complete protein glycosylation in the Golgi stack and proper sorting at the trans-Golgi network PMID: 23552074
    6. GRASP55 may function as an adaptor protein coupling MT1-MMP with furin, thus leading to the activation of the zymogen. PMID: 20608975
    7. These results demonstrate that GRASP55 and GRASP65 stack mammalian Golgi cisternae via a common mechanism. PMID: 20083603
    8. Data demonstrate that both GRASP55 and 65 are needed for the efficient transport to and through the Golgi complex, thus highlighting a novel role for the GRASPs in membrane trafficking. PMID: 19840934
    9. GRASP65 is an important structural component required for maintenance of Golgi apparatus integrity PMID: 11815631
    10. MEK1/ERK regulation of GRASP55-mediated Golgi linking is a control point in cell cycle progression PMID: 18434598
    11. GRASP55 forms an effector complex for the small GTPase rab2, together with a conserved coiled-coil protein golgin-45 (JEM-1). PMID: 11739401

    顯示更多

    收起更多

  • 亞細胞定位:
    Golgi apparatus membrane; Lipid-anchor. Endoplasmic reticulum membrane. Golgi apparatus.
  • 蛋白家族:
    GORASP family
  • 數據庫鏈接:

    HGNC: 17500

    OMIM: 608693

    KEGG: hsa:26003

    STRING: 9606.ENSP00000234160

    UniGene: Hs.431317



主站蜘蛛池模板: 久久综合伊人九色综合| 国产老熟女伦老熟妇露脸| 久久婷婷色综合一区二区| 中国精品偷拍区偷拍无码| 99视频精品全部免费免费观看| 污污网站18禁在线永久免费观看| 柠檬福利第一导航在线| 国产精品久久一区二区三区| 亚洲欧美一区二区三区在线| 国产精品无码2021在线观看| 亚洲日韩成人无码不卡网站| 日本一区二区三区免费高清| 日韩中文字幕在线一区二区三区 | 日韩欧群交p片内射中文| 女人18毛片水真多| 亚洲aⅴ在线无码天堂777| 羞涩的丰满人妻40p| 特级毛片在线大全免费播放| 久久精品天天中文字幕人妻| 综合久久国产九一剧情麻豆| 精品久久久无码中文字幕一丶| 亚洲最大av网站在线观看| 亚洲色偷精品一区二区三区| 直接观看黄网站免费视频| 亚洲 综合 自拍 精品 在线| 成av人片一区二区三区久久| 成人精品视频一区二区三区尤物| 久久天堂av综合合色蜜桃网| 国产美女精品视频线免费播放| 欧美牲交a欧美牲交aⅴ久久| 婷婷成人丁香五月综合激情| 久久婷婷人人澡人人爽人人喊| 国产成人国产在线观看| 搡老岳熟女国产熟妇| 欧美亚洲日韩国产综合电影| 把腿张开老子臊烂你多p视频| 情侣做性视频在线播放| 先锋影音xfyy5566男人资源| 男女扒开双腿猛进入免费看污| 欧美日韩精品| 国产午夜三级一区二区三|