在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Golgi reassembly-stacking protein 2 (GORASP2)

Recombinant Human Golgi reassembly-stacking protein 2 (GORASP2)

  • 中文名稱：
    人GORASP2重組蛋白
  • 貨號：
    CSB-YP880999HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人GORASP2重組蛋白
  • 貨號：
    CSB-EP880999HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人GORASP2重組蛋白
  • 貨號：
    CSB-EP880999HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人GORASP2重組蛋白
  • 貨號：
    CSB-BP880999HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人GORASP2重組蛋白
  • 貨號：
    CSB-MP880999HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    GORASP2
  • Uniprot No.：
  • 別名：
    AW552058; DKFZp434D156; FLJ13139; Golgi phosphoprotein 6; Golgi reassembly stacking protein 2; Golgi reassembly stacking protein 2; 55kDa; Golgi reassembly stacking protein of 55 kDa; Golgi reassembly-stacking protein 2; Golgi reassembly-stacking protein of 55 kDa; GOLPH2; GOLPH6; GORASP2; GORS2_HUMAN; GRASP55; GRS2; p59; RP23-428O15.1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-452
  • 氨基酸序列
    GSSQSVEIP GGGTEGYHVL RVQENSPGHR AGLEPFFDFI VSINGSRLNK DNDTLKDLLK ANVEKPVKML IYSSKTLELR ETSVTPSNLW GGQGLLGVSI RFCSFDGANE NVWHVLEVES NSPAALAGLR PHSDYIIGAD TVMNESEDLF SLIETHEAKP LKLYVYNTDT DNCREVIITP NSAWGGEGSL GCGIGYGYLH RIPTRPFEEG KKISLPGQMA GTPITPLKDG FTEVQLSSVN PPSLSPPGTT GIEQSLTGLS ISSTPPAVSS VLSTGVPTVP LLPPQVNQSL TSVPPMNPAT TLPGLMPLPA GLPNLPNLNL NLPAPHIMPG VGLPELVNPG LPPLPSMPPR NLPGIAPLPL PSEFLPSFPL VPESSSAASS GELLSSLPPT SNAPSDPATT TAKADAASSL TVDVTPPTAK APTTVEDRVG DSTPVSEKPV SAAVDANASE SP
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Plays a role in the assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after breakdown during mitosis and meiosis. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA. Required for normal acrosome formation during spermiogenesis and normal male fertility, probably by promoting colocalization of JAM2 and JAM3 at contact sites between germ cells and Sertoli cells. Mediates ER stress-induced unconventional (ER/Golgi-independent) trafficking of core-glycosylated CFTR to cell membrane.
  • 基因功能參考文獻：
    1. Results demonstrate a critical role for GRASP55 and GRASP65 in maintaining the stacked structure of the Golgi, which is required for accurate posttranslational modifications in the Golgi. Additionally, the GRASP knockout cell lines developed in this study will be useful tools for studying the role of GRASP proteins in other important cellular processes. PMID: 28814501
    2. binding site at the cleft between the PDZ1 and PDZ2 domains of GRASP65 is dominated by hydrophobic interactions with GM130 that are not observed in the GRASP55-Golgin45 complex PMID: 28049725
    3. GRASP55 interacts with CD83 shortly after induction of dendritic cells maturation. PMID: 25701785
    4. Cisternal-specific functions of GRASP65 and GRASP55 in continuity, compartmentalization, and function of the Golgi ribbon. PMID: 24227884
    5. propose that GRASP55/65 are negative regulators of exocytic transport and that this slowdown helps to ensure more complete protein glycosylation in the Golgi stack and proper sorting at the trans-Golgi network PMID: 23552074
    6. GRASP55 may function as an adaptor protein coupling MT1-MMP with furin, thus leading to the activation of the zymogen. PMID: 20608975
    7. These results demonstrate that GRASP55 and GRASP65 stack mammalian Golgi cisternae via a common mechanism. PMID: 20083603
    8. Data demonstrate that both GRASP55 and 65 are needed for the efficient transport to and through the Golgi complex, thus highlighting a novel role for the GRASPs in membrane trafficking. PMID: 19840934
    9. GRASP65 is an important structural component required for maintenance of Golgi apparatus integrity PMID: 11815631
    10. MEK1/ERK regulation of GRASP55-mediated Golgi linking is a control point in cell cycle progression PMID: 18434598
    11. GRASP55 forms an effector complex for the small GTPase rab2, together with a conserved coiled-coil protein golgin-45 (JEM-1). PMID: 11739401

    顯示更多

    收起更多

  • 亞細胞定位：
    Golgi apparatus membrane; Lipid-anchor. Endoplasmic reticulum membrane. Golgi apparatus.
  • 蛋白家族：
    GORASP family
  • 數據庫鏈接：

    HGNC: 17500

    OMIM: 608693

    KEGG: hsa:26003

    STRING: 9606.ENSP00000234160

    UniGene: Hs.431317



主站蜘蛛池模板： 99大香伊乱码一区二区| 熟女熟妇伦av网站| 亚洲日韩色在线影院性色| 日本二区三区欧美亚洲国产| 色偷偷av亚洲男人的天堂| 国产日产欧洲无码视频| 亚洲国产美国国产综合一区| 国产精品人妻在线观看| 欧美xxxx做受性欧美88| 国产精品免费无遮挡无码永久视频| 欧洲亚洲1卡二卡三卡2021| 亚洲成av人影院无码不卡| 性xxxx18免费观看视频| 国产av精国产传媒| 52熟女露脸国语对白视频| 久久97久久97精品免视看| 成人免费无码大片a毛片抽搐色欲| 国产精品青青在线观看爽香蕉| 国内精品乱码卡一卡2卡麻豆| 色99久久久久高潮综合影院| 天天躁日日躁狠狠躁av| 国产gv在线观看受被做哭| 人妻 偷拍 无码 中文字幕| 少妇被躁爽到高潮无码文| 波多野结衣在线播放| 久久综合给合久久狠狠狠88 | 亚洲精品久久久蜜桃| 7777精品伊久久久大香线蕉| 伊人久久精品无码麻豆一区| 色婷婷综合中文久久一本| 国产精品99久久精品| 国精产品69永久中国有限| 99久久久无码国产精品9| 午夜福利国产成人无码gif动图| 亚洲精品拍拍央视网出文| 舌头伸进去搅动好爽视频| 九九久久精品国产av片国产| 五月色丁香婷婷网蜜臀av| 成人免费播放视频777777| 少妇与大狼拘作爱性a| 最新色国产精品精品视频|