在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Glypican-6 (GPC6)

  • 中文名稱:
    人GPC6重組蛋白
  • 貨號:
    CSB-BP009708HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人GPC6重組蛋白
  • 貨號:
    CSB-EP009708HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人GPC6重組蛋白
  • 貨號:
    CSB-MP009708HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    GPC6
  • Uniprot No.:
  • 別名:
    GPC 6; Glypican 6 [Precursor]; Glypican proteoglycan 6; Gpc6; GPC6_HUMAN; MGC126288 ; OMIMD1; PRO705; Secreted glypican 6; Secreted glypican-6; UNQ369
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Glypican-6
  • 表達(dá)區(qū)域:
    24-529aa
  • 氨基酸序列
    DVKARSCGEVRQAYGAKGFSLADIPYQEIAGEHLRICPQEYTCCTTEMEDKLSQQSKLEFENLVEETSHFVRTTFVSRHKKFDEFFRELLENAEKSLNDMFVRTYGMLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWARLLERMFQLINPQYHFSEDYLECVSKYTDQLKPFGDVPRKLKIQVTRAFIAARTFVQGLTVGREVANRVSKVSPTPGCIRALMKMLYCPYCRGLPTVRPCNNYCLNVMKGCLANQADLDTEWNLFIDAMLLVAERLEGPFNIESVMDPIDVKISEAIMNMQENSMQVSAKVFQGCGQPKPAPALRSARSAPENFNTRFRPYNPEERPTTAAGTSLDRLVTDIKEKLKLSKKVWSALPYTICKDESVTAGTSNEEECWNGHSKARYLPEIMNDGLTNQINNPEVDVDITRPDTFIRQQIMALRVMTNKLKNAYNGNDVNFQDTSDESSGSGSGSGCMDDVCPTEFEFVTTEAPAVDPDRREVDS
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Cell surface proteoglycan that bears heparan sulfate. Putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases. Enhances migration and invasion of cancer cells through WNT5A signaling.
  • 基因功能參考文獻(xiàn):
    1. Thus, GPC6 and TMEM132D may serve as predictors of CD8+ T-lymphocyte infiltration and as favorable prognostic markers in early stage ovarian cancer with important consequences for diagnosis. PMID: 26448945
    2. Extracellular matrix proteins expression profiling in chemoresistant variants of the A2780 ovarian cancer cell line. PMID: 24804215
    3. GPC6 promotes invasive migration by inhibition of canonical beta-catenin and Wnt signalling, and up-regulation of non-canonical Wnt5A signalling leading to the activation of JNK and p38 MAPK. PMID: 21871017
    4. a reduction in GPC6 mRNA in retinoblastoma is associated with the non-random allelic loss at 13q31 that could contribute to RB development. PMID: 19726429
    5. Mutations in the heparan-sulfate proteoglycan glypican 6 impair endochondral ossification and cause recessive omodysplasia PMID: 19481194

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Omodysplasia 1 (OMOD1)
  • 亞細(xì)胞定位:
    Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.; [Secreted glypican-6]: Secreted, extracellular space.
  • 蛋白家族:
    Glypican family
  • 組織特異性:
    Widely expressed. High expression in fetal kidney and lung and lower expressions in fetal liver and brain. In adult tissues, very abundant in ovary, high levels also observed in liver, kidney, small intestine and colon. Not detected in peripheral blood le
  • 數(shù)據(jù)庫鏈接:

    HGNC: 4454

    OMIM: 258315

    KEGG: hsa:10082

    STRING: 9606.ENSP00000366246

    UniGene: Hs.444329



主站蜘蛛池模板: 久久久亚洲精品无码| 少妇太爽了在线观看| 国产精品久久久久久亚洲影视内衣 | 中文字幕人妻色偷偷久久| 3d动漫精品啪啪一区二区| 狠狠色成人一区二区三区| 亚洲欧美中文字幕日韩一区二区| 亚洲欧美中文字幕日韩一区二区| 香蕉久久人人爽人人爽人人片av| 韩国美女视频黄是免费| 国产精品亚洲а∨无码播放| 久久久久人妻精品区一三寸| 狠狠综合久久综合88亚洲| 99久久人妻精品免费二区| 最新版天堂资源中文官网 | 四虎影库久免费视频| 亚洲国产成人无码网站大全| 久久96国产精品久久久| 亚洲国产成人最新精品| 国产亚洲综合欧美一区二区| 欧美男生射精高潮视频网站 | 国产丰满乱子伦无码专区| 亚洲跨种族黑人xxxxx| 久久久精品午夜免费不卡| 天堂俺去俺来也www色官网| 五月丁香六月综合缴情在线| 无码潮喷a片无码高潮视频| 国产成人久久av免费高潮| 国精产品999一区二区三区有限| 精品国产一区二区三区国产区| 亚洲肥老太bbw中国熟女| 欧美自拍嘿咻内射在线观看| 日本久久综合久久综合| 亚洲色无码中文字幕在线| 色偷偷人人澡人人爽人人模 | 中文字幕乱码一区二区三区免费| 免费大香伊蕉在人线国产卡| 丰满人妻被黑人猛烈进入| 色综合色欲色综合色综合色综合r| 东京热加勒比视频一区| 国产精品久久久久aaaa|