在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Glucagon-like peptide 2 receptor (GLP2R), partial

Recombinant Human Glucagon-like peptide 2 receptor (GLP2R), partial

  • 中文名稱：
    人GLP2R重組蛋白
  • 貨號：
    CSB-YP009515HU1
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人GLP2R重組蛋白
  • 貨號：
    CSB-EP009515HU1
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人GLP2R重組蛋白
  • 貨號：
    CSB-EP009515HU1-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人GLP2R重組蛋白
  • 貨號：
    CSB-BP009515HU1
  • 規格：
  • 來源：
    Baculovirus
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    GLP2R; Glucagon-like peptide 2 receptor; GLP-2 receptor; GLP-2-R; GLP-2R
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    This is a receptor for glucagon-like peptide 2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
  • 基因功能參考文獻：
    1. GLP2R expression was significantly increased in gastric chief cells in OB and OWD patients. PKCzeta expression was also significantly increased. This is the first evidence of increased GLP2R expression in chief cells of patients with severe obesity regardless of diabetes status. PMID: 28337026
    2. GLP-2 augmented BRIN BD11 beta-cell proliferation, but was less efficacious in 1.1B4 cells. These data highlight the involvement of GLP-2 receptor signalling in the adaptations to pancreatic islet cell stress. PMID: 28746825
    3. This is the first time that human Epicardial adipose tissue is found to express both GLP-1R and GLP-2R genes. PMID: 28514806
    4. Report gastrointestinal GLP-2 receptor and limited utility of GLP-2 in the management of inflammatory intestinal disorders. PMID: 24875097
    5. GLP-2 receptors are highly expressed in gastrointestinal stromal tumors and Crohn's disease. PMID: 22951144
    6. GLP2R encodes a G protein-coupled receptor and involved in proliferative and anti-apoptotic cellular responses. PMID: 21326311
    7. docking studies were performed between the N-terminal extracellular domain of GLP-2 receptor and the GLP-2 hormone PMID: 21167157
    8. glucagon-like peptide-2 receptor is coupled to regulation of apoptosis and ERK1/2 activation through divergent signaling pathways PMID: 15471943
    9. GLP-2 in the gut acts by activating receptors on the subepithelial myofibroblasts, causing the release of growth factors, which in turn stimulate intestinal growth PMID: 15544847
    10. GLP-2 receptor C terminus has a role in modulating beta-arrestin-2 association but not ligand-induced desensitization, endocytosis, and G-protein-dependent effector activation PMID: 15817468
    11. GLP-2-induced stimulation of blood flow is mediated by vasoactive neurotransmitters that are colocalized with GLP-2R in 2 functionally distinct cell types within the gastrointestinal tract PMID: 16401478
    12. Endogenously expressing GLP-2 receptor encoding mRNA and protein was identified in intestinal cell lines. PMID: 16448646
    13. Sustained direct or indirect modulation of GLP-2R signaling does not modify intestinal tumor cell growth or survival. PMID: 18829546

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 2 family
  • 數據庫鏈接：

    HGNC: 4325

    OMIM: 603659

    KEGG: hsa:9340

    STRING: 9606.ENSP00000262441

    UniGene: Hs.248202



主站蜘蛛池模板： 国产成人无码午夜福利在线直播 | 国产免费又黄又爽又色毛| 国产一线二线三线女| 国产av精国产传媒| 精品国产你懂的在线观看| 在线成 人av影院| 免费无码毛片一区二区三区a片| 三男一女吃奶添下面视频| 免费精品国偷自产在线在线| 成人h无码动漫超w网站| 久久久精品人妻一区二区三区蜜桃 | 熟女俱乐部五十路六十路| 中文国产成人精品久久app| 亚洲日韩成人av无码网站| 自拍偷在线精品自拍偷99| 四虎永久在线精品884aa| 亚洲综合伊人久久大杳蕉| 人妻激情另类乱人伦人妻| 国产清纯白嫩初高生在线观看| 免费观看男女性高视频| 性做久久久久久久| 中文在线а√在线| 亚洲美女高清aⅴ视频免费| 18级成人毛片免费观看| 国色天香中文字幕在线视频| 久爱无码精品免费视频在线观看| 久久人人爽人人爽爽久久小说| 欧美无人区码suv| 艳妇乳肉豪妇荡乳av无码福利| 亚洲精品无码成人网站| 色天使久久综合给合久久97色 | 国产欧美另类久久久精品图片| 日本丰满少妇bbb| 色妺妺在线视频| 国产精品怡红院在线观看| 无码日韩人妻av一区免费| 无码人妻av免费一区二区三区| 亚洲一区二区三区av无码| 三级理论中文字幕在线播放 | 精品午夜福利1000在线观看| 无码国产精品一区二区免费vr|