在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Gamma-glutamylcyclotransferase (GGCT)

Recombinant Human Gamma-glutamylcyclotransferase (GGCT)

  • 中文名稱(chēng)：
    人GGCT重組蛋白
  • 貨號(hào)：
    CSB-YP009387HU
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱(chēng)：
    人GGCT重組蛋白
  • 貨號(hào)：
    CSB-EP009387HU-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱(chēng)：
    人GGCT重組蛋白
  • 貨號(hào)：
    CSB-BP009387HU
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱(chēng)：
    人GGCT重組蛋白
  • 貨號(hào)：
    CSB-MP009387HU
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    GGCT
  • Uniprot No.：
  • 別名：
    C7orf24; CRF21; Cytochrome c-releasing factor 21; Gamma glutamyl cyclotransferase; Gamma-glutamylcyclotransferase; GCTG; GGC; Ggct; GGCT_HUMAN
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度：
    Full length protein
  • 表達(dá)區(qū)域：
    1-188
  • 氨基酸序列
    MANSGCKDVT GPDEESFLYF AYGSNLLTER IHLRNPSAAF FCVARLQDFK LDFGNSQGKT SQTWHGGIAT IFQSPGDEVW GVVWKMNKSN LNSLDEQEGV KSGMYVVIEV KVATQEGKEI TCRSYLMTNY ESAPPSPQYK KIICMGAKEN GLPLEYQEKL KAIEPNDYTG KVSEEIEDII KKGETQTL
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis.
  • 基因功能參考文獻(xiàn)：
    1. GGCT is highly upregulated in HGSC tissues and associated with FIGO stage, lymph node metastasis and ascitic fluid volume. High expression of GGCT is associated with poor survival in HGSC patients. PMID: 29429592
    2. Taken together, the results indicate that PHB2 plays a central role in p21 upregulation following GGCT knockdown and as such may promote deregulated proliferation of cancer cells by suppressing p21. PMID: 29307834
    3. GGCT plays a critical role in glioma cell proliferation and may be a potential cancer therapeutic target. PMID: 26828272
    4. GGCT is promising as a diagnostic marker and a therapeutic target for various cancers. This review summarizes these interesting findings. PMID: 26339607
    5. G6PD, GGCT, IDH1, isocitrate dehydrogenase 2 (NADP+,mitochondrial) (IDH2) and glutathione S-transferase pi 1(GSTP1), five of the critical components of GSH pathway, contribute to chemoresistance. PMID: 25818003
    6. GGCT plays a critical role in lung cancer cell proliferation. PMID: 25941902
    7. Transcriptional silencing of the C7orf24 gene in the non-malignant cells is elicited through heterochromatin formation in its promoter region. PMID: 23853312
    8. increased expression of GGCT was a common event among invasive esophageal squamous cell carcinoma tissues regardless of the depth of invasion. Lymph node metastasis and tumor differentiation correlated with GGCT expression PMID: 24342434
    9. C7orf24 has been recognized as a potent marker for bladder and breast cancers. Studies on the role of gamma-glutamylcyclotransferace may aid in the control of malignant transformation of these cancers. PMID: 23513927
    10. GGCT may be a biomarker of tumors in a limited range of organs. PMID: 22205682
    11. C7orf24 overexpression defines a subgroup of breast tumors with poor clinical outcome. PMID: 20527979
    12. CRF21 might play an important role in the induction of apoptosis by GGO in leukemia U937 cells. PMID: 16765912
    13. presence of extra electron density/ligands and conservation at the sequence and structure levels, it is likely that the cavity has a crucial role in the function of LOC79017 and its structural neighbors possibly as an active site or ligand-binding site PMID: 17932939
    14. The GGCT gene is located on chromosome 7p14-15 and consists of four exons that span 8 kb, the primary sequence is 188 amino acids in length and is unlike any protein of known function PMID: 18515354

    顯示更多

    收起更多

  • 蛋白家族：
    Gamma-glutamylcyclotransferase family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 21705

    OMIM: 137170

    KEGG: hsa:79017

    STRING: 9606.ENSP00000275428

    UniGene: Hs.530024



主站蜘蛛池模板： 欧美第一黄网免费网站| 亚洲综合伊人久久大杳蕉| 99re久久资源最新地址| 国产精品 自在自线| 688欧美人禽杂交狂配| 免费毛儿一区二区十八岁| 毛片免费视频观看| 99久久综合狠狠综合久久| 亚洲 另类 在线 欧美 制服| 中文字幕人妻第一区| 99在线精品国自产拍| 久久亚洲中文字幕无码| 97免费公开在线视频| 永久免费无码国产| 国产精品午夜剧场免费观看| 熟女少妇丰满一区二区| 亚洲日韩成人无码| 精品无人区一区二区三区在线| 国产av福利久久| 日本黄网站免费| 一 级做人爱全视频在线看 | 99麻豆久久久国产精品免费| 亚洲人成人伊人成综合网无码| 国产亚洲精品久久久久久彩霞| 中文字幕在线精品视频| 小sao货水好多真紧h视频| 国内揄拍国产精品人妻门事件| 97se亚洲综合自在线| 免费国产黄线在线观看| 久久欧美一区二区三区性生奴| 寂寞骚妇被后入式爆草抓爆 | 国精品99久9在线 | 免费| 久久精品人人做人人爽| 亚洲欧美日韩综合一区| 青青草国产线观看| 暴力强奷在线播放无码| 久久综合九色综合久99| 偷看少妇自慰xxxx| 中文字幕日韩人妻不卡一区| 欧洲人妻丰满av无码久久不卡| 久久精品女人天堂av|