在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GGCT Antibody, FITC conjugated

  • 中文名稱:
    GGCT兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA009387LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GGCT Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    GGCT
  • 別名:
    C7orf24 antibody; CRF21 antibody; Cytochrome c-releasing factor 21 antibody; Gamma glutamyl cyclotransferase antibody; Gamma-glutamylcyclotransferase antibody; GCTG antibody; GGC antibody; Ggct antibody; GGCT_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Gamma-glutamylcyclotransferase protein (54-188AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis.
  • 基因功能參考文獻:
    1. GGCT is highly upregulated in HGSC tissues and associated with FIGO stage, lymph node metastasis and ascitic fluid volume. High expression of GGCT is associated with poor survival in HGSC patients. PMID: 29429592
    2. Taken together, the results indicate that PHB2 plays a central role in p21 upregulation following GGCT knockdown and as such may promote deregulated proliferation of cancer cells by suppressing p21. PMID: 29307834
    3. GGCT plays a critical role in glioma cell proliferation and may be a potential cancer therapeutic target. PMID: 26828272
    4. GGCT is promising as a diagnostic marker and a therapeutic target for various cancers. This review summarizes these interesting findings. PMID: 26339607
    5. G6PD, GGCT, IDH1, isocitrate dehydrogenase 2 (NADP+,mitochondrial) (IDH2) and glutathione S-transferase pi 1(GSTP1), five of the critical components of GSH pathway, contribute to chemoresistance. PMID: 25818003
    6. GGCT plays a critical role in lung cancer cell proliferation. PMID: 25941902
    7. Transcriptional silencing of the C7orf24 gene in the non-malignant cells is elicited through heterochromatin formation in its promoter region. PMID: 23853312
    8. increased expression of GGCT was a common event among invasive esophageal squamous cell carcinoma tissues regardless of the depth of invasion. Lymph node metastasis and tumor differentiation correlated with GGCT expression PMID: 24342434
    9. C7orf24 has been recognized as a potent marker for bladder and breast cancers. Studies on the role of gamma-glutamylcyclotransferace may aid in the control of malignant transformation of these cancers. PMID: 23513927
    10. GGCT may be a biomarker of tumors in a limited range of organs. PMID: 22205682
    11. C7orf24 overexpression defines a subgroup of breast tumors with poor clinical outcome. PMID: 20527979
    12. CRF21 might play an important role in the induction of apoptosis by GGO in leukemia U937 cells. PMID: 16765912
    13. presence of extra electron density/ligands and conservation at the sequence and structure levels, it is likely that the cavity has a crucial role in the function of LOC79017 and its structural neighbors possibly as an active site or ligand-binding site PMID: 17932939
    14. The GGCT gene is located on chromosome 7p14-15 and consists of four exons that span 8 kb, the primary sequence is 188 amino acids in length and is unlike any protein of known function PMID: 18515354

    顯示更多

    收起更多

  • 蛋白家族:
    Gamma-glutamylcyclotransferase family
  • 數據庫鏈接:

    HGNC: 21705

    OMIM: 137170

    KEGG: hsa:79017

    STRING: 9606.ENSP00000275428

    UniGene: Hs.530024



主站蜘蛛池模板: 香蕉av777xxx色综合一区| 精品av一区二区久久久| 国产97人人超碰caoprom| 久久久久99精品成人品| 制服丝袜亚洲欧美中文字幕| 在线看片福利无码网址| 性色av无码一区二区三区人妻| 免费看成人欧美片爱潮app| 亚洲国产成人av人片久久| 国产精品久久国产精品99盘| 四虎www永久在线精品| 无码一区二区三区在线| 亚洲国产av无码精品无广告| 亚洲第一网站男人都懂| 成人午夜免费无码区| 四虎www成人影院观看| 97久久精品人人澡人人爽| 久精品国产欧美亚洲色aⅴ大片| 亚洲精品欧美综合一区二区| 亚洲欧美国产va在线播放| 欧美人与动牲交aⅴ| 韩产日产国产欧产| 国产日韩欧美亚洲精品中字| 日韩成人无码v清免费| 野外性史欧美k8播放| 国产伦久视频免费观看视频| 亚洲人成色4444在线观看| www国产亚洲精品久久| 久久无码中文字幕免费影院| 久久久久久久久久久综合日本| 国产人妖视频一区二区| 久久久久久久女国产乱让韩| 少妇和邻居做不戴套视频| 香港三级日本三级韩级人妇| 性色av免费网站| 欧美性猛交xxxx免费视频软件 | 日本在线高清不卡免费播放| 国产做a爰片久久毛片a片白丝| 少妇激情作爱视频| 强行糟蹋人妻hd中文字幕| 亚洲精品久久久久久无码色欲四季|