在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human GTP-binding protein GEM (GEM)

Recombinant Human GTP-binding protein GEM (GEM)

  • 中文名稱(chēng)：
    人GEM重組蛋白
  • 貨號(hào)：
    CSB-YP009362HU
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱(chēng)：
    人GEM重組蛋白
  • 貨號(hào)：
    CSB-EP009362HU
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱(chēng)：
    人GEM重組蛋白
  • 貨號(hào)：
    CSB-EP009362HU-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱(chēng)：
    人GEM重組蛋白
  • 貨號(hào)：
    CSB-BP009362HU
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱(chēng)：
    人GEM重組蛋白
  • 貨號(hào)：
    CSB-MP009362HU
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    GEM
  • Uniprot No.：
  • 別名：
    GEM; KIRGTP-binding protein GEM; GTP-binding mitogen-induced T-cell protein; RAS-like protein KIR
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度：
    Full length protein
  • 表達(dá)區(qū)域：
    1-296
  • 氨基酸序列
    MTLNNVTMRQ GTVGMQPQQQ RWSIPADGRH LMVQKEPHQY SHRNRHSATP EDHCRRSWSS DSTDSVISSE SGNTYYRVVL IGEQGVGKST LANIFAGVHD SMDSDCEVLG EDTYERTLMV DGESATIILL DMWENKGENE WLHDHCMQVG DAYLIVYSIT DRASFEKASE LRIQLRRARQ TEDIPIILVG NKSDLVRCRE VSVSEGRACA VVFDCKFIET SAAVQHNVKE LFEGIVRQVR LRRDSKEKNE RRLAYQKRKE SMPRKARRFW GKIVAKNNKN MAFKLKSKSC HDLSVL
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity.
  • 基因功能參考文獻(xiàn)：
    1. Down regulation of Gem expression was involved in the pathogenesis of hepatocellular carcinoma (HCC), and it might be a favorable independent prognostic parameter for HCC. PMID: 25155751
    2. These findings demonstrate a new role of Gem/Gmip/RhoA signaling in cortical actin regulation during early mitotic stages. PMID: 25173885
    3. Gem is involved both in T-cell spontaneous cell migration as well as chemotaxis and plays an important role in cell-to-cell HTLV-1 viral transmission. PMID: 24586148
    4. Data show a mechanism by which GTPase Gem contributes to the mitotic progression by maintaining correct spindle length through the kinesin Kif9. PMID: 22964304
    5. Gem contains two candidate inhibitory sites, each capable of producing full inhibition of P/Q-type Ca(2+) channels. PMID: 22589533
    6. GEM plays a key role during C. pneumoniae entry into human cells. PMID: 20233927
    7. We discuss the structural and functional properties of RGK proteins and highlight recent work addressing the mechanism of Gem regulation by calmodulin and 14-3-3. PMID: 16242932
    8. crystallographic structure and biochemical characterization indicate that Gem G-domain markedly prefers GDP over GTP PMID: 17052716
    9. Gem is a bona fide GTPase that exhibits striking structural and biochemical features that should impact its regulation and cellular activities PMID: 17107948

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    Small GTPase superfamily, RGK family
  • 組織特異性：
    Most abundant in thymus, spleen, kidney, lung, and testis. Less abundant in heart, brain, liver and skeletal muscle.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 4234

    OMIM: 600164

    KEGG: hsa:2669

    STRING: 9606.ENSP00000297596

    UniGene: Hs.654463



主站蜘蛛池模板： 女人夜夜春高潮爽a∨片 | 国内精品伊人久久久久7777| 国产va免费精品高清在线| 国产午夜精品一区二区三区漫画| 精品丝袜国产自在线拍小草| 任我爽精品视频在线播放| 成人性生交大片免费看| 夜夜高潮夜夜爽夜夜爱| 少妇熟女高潮流白浆| 亚洲精品天天影视综合网| 狠狠做久久深爱婷婷| 亚洲成av人片在线观看无| 亚洲人成电影在线观看影院| 亚洲狠狠成人网| 久久精品国产精品亚洲38| 国产精品久久久久影院色 | 天天噜日日噜狠狠噜免费| 成人午夜高潮刺激免费视频| 欧美人与动牲交欧美精品| 国产真人做爰视频免费| 欧美黑人添添高潮a片www| 性强烈的欧美三级视频| 欧美处交wwwvideos另类| 无码国产一区二区免费| 亚洲婷婷综合色高清在线| 日韩人妻精品一区二区三区视频| 欧美性生交活xxxxxdddd| 亚洲国产三级在线观看| 99精品国产在热久久婷婷| 免费人成视频网站在线观看18| 国内精品久久久久影院优| 亚洲国产成人久久综合区| 欧美性猛交xxxx免费看| 久久中文字幕无码a片不卡古代 | 欧美噜噜久久久xxx| 久久精品国产99国产精品导航| 亚洲成a人片在线播放| 丰满多毛少妇做爰视频爽爽和| 国产亚洲精品久久久久久无几年桃| 久青草国产97香蕉在线影院| 婷婷色五月开心五月|