Recombinant Human FERM and PDZ domain-containing protein 4 (FRMPD4), partial

中文名稱：

人FRMPD4重組蛋白
貨號：

CSB-YP613537HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人FRMPD4重組蛋白
貨號：

CSB-EP613537HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人FRMPD4重組蛋白
貨號：

CSB-EP613537HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人FRMPD4重組蛋白
貨號：

CSB-BP613537HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人FRMPD4重組蛋白
貨號：

CSB-MP613537HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

FRMPD4
Uniprot No.：

Q14CM0
別名：

FERM and PDZ domain containing 4; FERM and PDZ domain-containing protein 4; Frmpd4; FRPD4_HUMAN; Gm196; KIAA0316; MGC142260; PDZ domain containing 10; PDZ domain containing protein 10; PDZ domain-containing protein 10; PDZD10; PDZK10; Preso; PSD 95 interacting FERM and PDZ domain protein; PSD 95 interacting regulator of spine morpogenesis; PSD-95-interacting regulator of spine morphogenesis; RGD1566031; RP23-217I22.2
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Positive regulator of dendritic spine morphogenesis and density. Required for the maintenance of excitatory synaptic transmission. Binds phosphatidylinositol 4,5-bisphosphate.
基因功能參考文獻：
1. Study suggests that the variant rs5979717 in FRMPD4 may play a role in schizophrenia etiology in females PMID: 26555035
2. A crystal structure of Frmpd4-bound LGN in an oxidized form is also reported, although oxidation does not appear to strongly affect the interaction with Frmpd4. PMID: 25664792
3. Preso positively regulates spine density through its interaction with the synaptic plasma membrane, actin filaments, PSD-95, and the betaPix-based Rac1 signaling pathway. PMID: 19118189
相關疾病：

Mental retardation, X-linked 104 (MRX104)
亞細胞定位：

Cell projection, dendritic spine.
數據庫鏈接：

HGNC: 29007

OMIM: 300838

KEGG: hsa:9758

STRING: 9606.ENSP00000370057

UniGene: Hs.657507