在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Eyes absent homolog 3 (EYA3)

  • 中文名稱:
    人EYA3重組蛋白
  • 貨號:
    CSB-YP860766HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人EYA3重組蛋白
  • 貨號:
    CSB-EP860766HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人EYA3重組蛋白
  • 貨號:
    CSB-EP860766HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人EYA3重組蛋白
  • 貨號:
    CSB-BP860766HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人EYA3重組蛋白
  • 貨號:
    CSB-MP860766HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    EYA3
  • Uniprot No.:
  • 別名:
    AI844637; DKFZp686C132; EYA3; EYA3_HUMAN; Eyes absent 3; Eyes absent 3 homolog (Drosophila) ; Eyes absent homolog 3; OTTMUSP00000010370; RP11-460I13.4; RP23-442A20.1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-573
  • 氨基酸序列
    MEEEQDLPEQ PVKKAKMQES GEQTISQVSN PDVSDQKPET SSLASNLPMS EEIMTCTDYI PRSSNDYTSQ MYSAKPYAHI LSVPVSETAY PGQTQYQTLQ QTQPYAVYPQ ATQTYGLPPF GALWPGMKPE SGLIQTPSPS QHSVLTCTTG LTTSQPSPAH YSYPIQASST NASLISTSST IANIPAAAVA SISNQDYPTY TILGQNQYQA CYPSSSFGVT GQTNSDAEST TLAATTYQSE KPSVMAPAPA AQRLSSGDPS TSPSLSQTTP SKDTDDQSRK NMTSKNRGKR KADATSSQDS ELERVFLWDL DETIIIFHSL LTGSYAQKYG KDPTVVIGSG LTMEEMIFEV ADTHLFFNDL EECDQVHVED VASDDNGQDL SNYSFSTDGF SGSGGSGSHG SSVGVQGGVD WMRKLAFRYR KVREIYDKHK SNVGGLLSPQ RKEALQRLRA EIEVLTDSWL GTALKSLLLI QSRKNCVNVL ITTTQLVPAL AKVLLYGLGE IFPIENIYSA TKIGKESCFE RIVSRFGKKV TYVVIGDGRD EEIAAKQHNM PFWRITNHGD LVSLHQALEL DFL
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. Coactivates SIX1, and seems to coactivate SIX2, SIX4 and SIX5. The repression of precursor cell proliferation in myoblasts by SIX1 is switched to activation through recruitment of EYA3 to the SIX1-DACH1 complex and seems to be dependent on EYA3 phosphatase activity. May be involved in development of the eye.
  • 基因功能參考文獻:
    1. Study identifies Eya3 as a regulator of PP2A, a major cellular Ser/Thr phosphatase, and uncovers a mechanism of controlling the stability of a critical oncogene, c-Myc. PMID: 29535359
    2. Benzbromarone metabolites and derivatives function as EYA3 inhibitory anti-angiogenic agents. PMID: 24367676
    3. These studies identify EYA3 as a novel mediator of chemoresistance in Ewing sarcoma and define the molecular mechanisms of both EYA3 overexpression and of EYA3-mediated chemoresistance PMID: 22723308
  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    HAD-like hydrolase superfamily, EYA family
  • 數據庫鏈接:

    HGNC: 3521

    OMIM: 601655

    KEGG: hsa:2140

    STRING: 9606.ENSP00000362978

    UniGene: Hs.185774



主站蜘蛛池模板: 3d动漫精品啪啪一区二区中| av天堂永久资源网| √最新版天堂资源在线| 亚拍精品一区二区三区探花| 欧美精品久久96人妻无码| 国产卡一卡二卡三| 色又黄又爽18禁免费网站现观看| 狼群社区www中文视频| 香草乱码一二三四区别| 色悠久久久久久久综合网| 荫蒂添的好舒服视频囗交| 国产模特嫩模私拍视频在线| 久久精品亚洲综合专区| 日本伊人精品一区二区三区| 日本久久久久久久做爰片日本| 久久视频这里只有精品在线观看| 日本精品aⅴ一区二区三区| 五月av综合av国产av| 2012中文字幕在线视频| 亚洲成av人片在线观看橙子| 国产精品无码久久久久久| 国产精品vr专区| 少妇夜夜春夜夜爽试看视频| 天天综合色天天综合色hd| 少妇性bbb搡bbb爽爽爽欧美| 久久精品人人槡人妻人| 欧美精品亚洲精品日韩专区| 国产成年无码v片在线| 久久99精品国产麻豆婷婷| 国产av无码专区亚洲草草| 欧洲精品成人免费视频在线观看| 国产v亚洲v天堂a无码| 国产 高潮 抽搐 正在播放 | 国产后进白嫩翘臀在线播放| 首页 国产 亚洲 丝袜图片区| 欧美黑人巨大videos精品| 亚洲性无码av在线欣赏网| 国产露脸精品产三级国产av| 久久久无码精品亚洲日韩啪啪网站| 学生妹亚洲一区二区| 日本国产网曝视频在线观看|