在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

EYA3 Antibody

  • 中文名稱:
    EYA3兔多克隆抗體
  • 貨號:
    CSB-PA007908GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    EYA3
  • 別名:
    AI844637 antibody; DKFZp686C132 antibody; EYA3 antibody; EYA3_HUMAN antibody; Eyes absent 3 antibody; Eyes absent 3 homolog (Drosophila) antibody; Eyes absent homolog 3 antibody; OTTMUSP00000010370 antibody; RP11-460I13.4 antibody; RP23-442A20.1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human EYA3
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. Coactivates SIX1, and seems to coactivate SIX2, SIX4 and SIX5. The repression of precursor cell proliferation in myoblasts by SIX1 is switched to activation through recruitment of EYA3 to the SIX1-DACH1 complex and seems to be dependent on EYA3 phosphatase activity. May be involved in development of the eye.
  • 基因功能參考文獻:
    1. Study identifies Eya3 as a regulator of PP2A, a major cellular Ser/Thr phosphatase, and uncovers a mechanism of controlling the stability of a critical oncogene, c-Myc. PMID: 29535359
    2. Benzbromarone metabolites and derivatives function as EYA3 inhibitory anti-angiogenic agents. PMID: 24367676
    3. These studies identify EYA3 as a novel mediator of chemoresistance in Ewing sarcoma and define the molecular mechanisms of both EYA3 overexpression and of EYA3-mediated chemoresistance PMID: 22723308
  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    HAD-like hydrolase superfamily, EYA family
  • 數據庫鏈接:

    HGNC: 3521

    OMIM: 601655

    KEGG: hsa:2140

    STRING: 9606.ENSP00000362978

    UniGene: Hs.185774



主站蜘蛛池模板: 在线 v亚洲 v欧美v 专区| 久久精品香蕉绿巨人登场| 成人免费无码不卡毛片视频| 无码国内精品久久综合88| 国产成人精品优优av| 精品无码久久久久国产手机版| 超碰97人人做人人爱亚洲尤物| 欧美成人www免费全部网站 | 欧美精品a∨在线观看| 久久久久久久精品成人热色戒汤唯 | 国产探花在线精品一区二区| 久久久精品妇女99| 2019午夜福利不卡片在线| av在线播放日韩亚洲欧| 国产成人免费97在线观看| 老汉色老汉首页a亚洲| 欧美 日韩版国产在线播放| 97人人模人人爽人人少妇| 成人看的污污超级黄网站免费| 免费无码午夜福利片69| 奶头又大又白喷奶水av| 亚洲国产成人一区二区在线| 两个美女裸体舌吻互扒内裤| 蜜桃麻豆www久久国产sex| 国产freexxxx性播放麻豆| 真人祼交二十三式视频| 日韩精品国产另类专区| 亚洲精品嫩草研究院久久| 熟睡人妻被讨厌的公侵犯| 青草影院内射中出高潮| 一本清日本在线视频精品| 天天爱天天做狠狠久久做| 成a人片亚洲日本久久| 美女mm131午夜福利在线| 日产精品久久久久久久蜜臀| 麻豆一区二区三区精品视频| 亚洲高清国产av拍精品青青草原 | 久久熟妇人妻午夜寂寞影院| 中国少妇videos呻吟| 搡老女人老妇女老熟妇| 人妻被按摩师玩弄到潮喷|