在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

EYA3 Antibody

  • 中文名稱:
    EYA3兔多克隆抗體
  • 貨號:
    CSB-PA007908GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    EYA3
  • 別名:
    AI844637 antibody; DKFZp686C132 antibody; EYA3 antibody; EYA3_HUMAN antibody; Eyes absent 3 antibody; Eyes absent 3 homolog (Drosophila) antibody; Eyes absent homolog 3 antibody; OTTMUSP00000010370 antibody; RP11-460I13.4 antibody; RP23-442A20.1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human EYA3
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. Coactivates SIX1, and seems to coactivate SIX2, SIX4 and SIX5. The repression of precursor cell proliferation in myoblasts by SIX1 is switched to activation through recruitment of EYA3 to the SIX1-DACH1 complex and seems to be dependent on EYA3 phosphatase activity. May be involved in development of the eye.
  • 基因功能參考文獻:
    1. Study identifies Eya3 as a regulator of PP2A, a major cellular Ser/Thr phosphatase, and uncovers a mechanism of controlling the stability of a critical oncogene, c-Myc. PMID: 29535359
    2. Benzbromarone metabolites and derivatives function as EYA3 inhibitory anti-angiogenic agents. PMID: 24367676
    3. These studies identify EYA3 as a novel mediator of chemoresistance in Ewing sarcoma and define the molecular mechanisms of both EYA3 overexpression and of EYA3-mediated chemoresistance PMID: 22723308
  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    HAD-like hydrolase superfamily, EYA family
  • 數據庫鏈接:

    HGNC: 3521

    OMIM: 601655

    KEGG: hsa:2140

    STRING: 9606.ENSP00000362978

    UniGene: Hs.185774



主站蜘蛛池模板: 亚洲精品久久国产精品| 海角社区在线视频播放观看| 国产免费艾彩sm调教视频| 人妻丰满熟妇av无码区不卡| 乱人伦无码中文视频在线| 国内精品自在自线视频| 女人另类牲交zozozo| 少妇无码一区二区三区| 国内精品久久久久影院薰衣草| a狠狠久久蜜臀婷色中文网| 中国少妇大p毛茸茸| 欧美午夜刺激影院| 日日噜噜噜夜夜爽爽狠狠视频| 国产美女嘘嘘嘘嘘嘘| 国产美女久久精品香蕉| 无码人妻黑人中文字幕| 一本一道人人妻人人妻αv| 国内精品久久久久伊人av| 香蕉蕉亚亚洲aav综合| 99热久久精里都是精品6| 人妻少妇精品久久| 日本体内she精高潮| 成年无码动漫av片在线观看羞羞| 无码国产玉足脚交极品播放| 熟妇无码熟妇毛片| 国产av无码国产av毛片| 亚洲日韩国产二区无码| 欧美506070老妇乱子伦| 婷婷色五月开心五月| 艳妇臀荡乳欲伦交换h在线观看 | 樱花草在线社区www韩国| 东京热加勒比视频一区| 日韩成人大屁股内射喷水 | 法国白嫩大屁股xxxx| 无码中字出轨中文人妻中文中| 好紧好湿好黄的视频| 色爱无码av综合区| 最新国产精品拍自在线观看| 777米奇色狠狠俺去啦奇米77| 国产av人人夜夜澡人人爽麻豆 | 国产尤物av尤物在线看|