在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

EYA3 Antibody

  • 中文名稱:
    EYA3兔多克隆抗體
  • 貨號:
    CSB-PA860766DSR2HU
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: EYA3 antibody at 2.88μg/ml
      Lane 1: Hela whole cell lysate
      Lane 2: 293T whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 63, 49, 59, 57, 58 kDa
      Observed band size: 63, 67 kDa
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA860766DSR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA860766DSR2HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) EYA3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    EYA3
  • 別名:
    AI844637 antibody; DKFZp686C132 antibody; EYA3 antibody; EYA3_HUMAN antibody; Eyes absent 3 antibody; Eyes absent 3 homolog (Drosophila) antibody; Eyes absent homolog 3 antibody; OTTMUSP00000010370 antibody; RP11-460I13.4 antibody; RP23-442A20.1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Eyes absent homolog 3 protein (1-300AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. Coactivates SIX1, and seems to coactivate SIX2, SIX4 and SIX5. The repression of precursor cell proliferation in myoblasts by SIX1 is switched to activation through recruitment of EYA3 to the SIX1-DACH1 complex and seems to be dependent on EYA3 phosphatase activity. May be involved in development of the eye.
  • 基因功能參考文獻:
    1. Study identifies Eya3 as a regulator of PP2A, a major cellular Ser/Thr phosphatase, and uncovers a mechanism of controlling the stability of a critical oncogene, c-Myc. PMID: 29535359
    2. Benzbromarone metabolites and derivatives function as EYA3 inhibitory anti-angiogenic agents. PMID: 24367676
    3. These studies identify EYA3 as a novel mediator of chemoresistance in Ewing sarcoma and define the molecular mechanisms of both EYA3 overexpression and of EYA3-mediated chemoresistance PMID: 22723308
  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    HAD-like hydrolase superfamily, EYA family
  • 數據庫鏈接:

    HGNC: 3521

    OMIM: 601655

    KEGG: hsa:2140

    STRING: 9606.ENSP00000362978

    UniGene: Hs.185774



主站蜘蛛池模板: 精品久久久久久无码人妻蜜桃 | 天堂va欧美ⅴa亚洲va在线| 欧美做受又硬又粗又大视频| 国产午夜福利短视频| 国产精品无码久久久久久| 爱做久久久久久| 亚洲乱码中文字幕在线| 国产av亚洲精品久久久久久| 国语对白嫖老妇胖老太| 国产偷v国产偷v亚洲高清| 无码人妻丰满熟妇啪啪网站| 人人爽久久涩噜噜噜av| 精品一区二区成人精品| 亚瑟国产精品久久| 中日韩高清无专码区2021| 日韩精品无码久久久久久| 亚洲高清一区二区三区不卡| 丰满熟女人妻中文字幕免费| 天天天欲色欲色www免费| 亚洲毛片无码不卡av在线播放| 中本亚洲欧美国产日韩| 亚洲成a人片在线观看国产| 久久久久久久极品内射| 国产成人精品日本亚洲 | 国产成人精品手机在线观看| 国产三级av在线播放| 熟妇人妻午夜寂寞影院| 中文字幕丰满乱子无码视频| 一区二区在线欧美日韩中文| 国产精品人成视频免费999| 日韩人妻精品一区二区三区视频| 久久俺也去丁香综合色| 久久精品国产一区二区电影| 99国产精品自在自在久久| 午夜尤物禁止18点击进入| 国产在线视频一区二区三区98| 伦埋琪琪电影院久久| 中文字幕av中文字无码亚| av国産精品毛片一区二区视频 | 国产亚洲精aa在线观看see| av人摸人人人澡人人超碰下载|