在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Eukaryotic translation initiation factor 3 subunit C (EIF3C), partial

  • 中文名稱:
    人EIF3C重組蛋白
  • 貨號:
    CSB-YP857867HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人EIF3C重組蛋白
  • 貨號:
    CSB-EP857867HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人EIF3C重組蛋白
  • 貨號:
    CSB-EP857867HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人EIF3C重組蛋白
  • 貨號:
    CSB-BP857867HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人EIF3C重組蛋白
  • 貨號:
    CSB-MP857867HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    EIF3C
  • Uniprot No.:
  • 別名:
    Cell migration inducing protein 17; eIF 3c; eIF3 p110; eIF3-p110; eIF3c; EIF3C_HUMAN; EIF3CL; EIF3S8; EIF3S8 protein; Eukaryotic translation initiation factor 3 subunit 8 (110kD); Eukaryotic translation initiation factor 3 subunit 8 110kDa; Eukaryotic translation initiation factor 3 subunit 8; Eukaryotic translation initiation factor 3 subunit C
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
  • 基因功能參考文獻:
    1. In EIF3C-positive tumors, 32 out of 42 showed significantly higher frequencies of high grade group by immunoreactivity. PMID: 28854163
    2. High eIF3c expression is positively associated with KRAS. PMID: 28231410
    3. These findings suggest that eIF3c is overexpressed in human gliomas and essential for their proliferation and survival. PMID: 25823503
    4. eukaryotic initiation factor 4G (eIF4G) protein binds to eIF3c, -d, and -e to promote mRNA recruitment to the ribosome. PMID: 24092755
    5. Collectively, eIF3c deletion effectively reduced the survival of colon cancer cells and could be used as a therapeutic tool for colon cancer therapy. PMID: 23733421
    6. These results indicate that the interaction between Hsp90 and eIF3c may play an important role in hepatitis C virus internal ribosome entry site-mediated translation. PMID: 22016036

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    EIF-3 subunit C family
  • 數據庫鏈接:

    HGNC: 3279

    OMIM: 603916

    KEGG: hsa:8663

    STRING: 9606.ENSP00000332604

    UniGene: Hs.567374



主站蜘蛛池模板: 国产又色又爽又黄好看的视频| 2020无码天天喷水天天爽| 亚洲欧美在线观看| 亚洲日韩v无码中文字幕 | 国产精品爽爽久久久久久蜜臀| 在线观看欧美一区二区三区| 久久本色成人综合网| 国产精品18久久久久久欧美| 人妻互换一二三区激情视频 | 超清制服丝袜无码av福利网| 久久人人爽爽人人爽人人片av| 中文字幕乱码人妻综合二区三区| 天天躁日日躁狠狠很躁| 精品久久一区二区乱码| 最新亚洲一卡二卡三卡四卡| 国产女女做受ⅹxx高潮| 中国产xxxxa片在线观看| 国产精品香蕉在线观看| 国产精品免费观看调教网| 人妻熟女一区二区aⅴ清水理纱| 99久久久无码国产精品6| 亚洲人成小说网站色在线| 亚洲人成77在线播放网站| 丰满多毛少妇做爰视频爽爽和 | 波多野结衣免费一区视频| a片免费视频在线观看| 真人做作爱视频| 乱码精品一区二区三区| 亚洲精品国偷自产在线| 波多野结衣久久一区二区| 国产一区二区三区在线视頻| 狠狠噜天天噜日日噜视频麻豆 | 奇米777四色在线精品| 日本japanese漂亮丰满| 国产女人高潮叫床视频| 亲子乱av一区二区三区 | 日韩人妻少妇一区二区| 亚洲成a人v影院色老汉影院 | 国产片a国产片免费看视频| 国产日产精品一区二区三区四区的特点 | 亚洲精品国产第一区第二|