在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

EIF3C Antibody

  • 中文名稱:
    EIF3C兔多克隆抗體
  • 貨號:
    CSB-PA007531GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    EIF3C
  • 別名:
    Cell migration inducing protein 17 antibody; eIF 3c antibody; eIF3 p110 antibody; eIF3-p110 antibody; eIF3c antibody; EIF3C_HUMAN antibody; EIF3CL antibody; EIF3S8 antibody; EIF3S8 protein antibody; Eukaryotic translation initiation factor 3 subunit 8 (110kD) antibody; Eukaryotic translation initiation factor 3 subunit 8 110kDa antibody; Eukaryotic translation initiation factor 3 subunit 8 antibody; Eukaryotic translation initiation factor 3 subunit C antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human EIF3C
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
  • 基因功能參考文獻:
    1. In EIF3C-positive tumors, 32 out of 42 showed significantly higher frequencies of high grade group by immunoreactivity. PMID: 28854163
    2. High eIF3c expression is positively associated with KRAS. PMID: 28231410
    3. These findings suggest that eIF3c is overexpressed in human gliomas and essential for their proliferation and survival. PMID: 25823503
    4. eukaryotic initiation factor 4G (eIF4G) protein binds to eIF3c, -d, and -e to promote mRNA recruitment to the ribosome. PMID: 24092755
    5. Collectively, eIF3c deletion effectively reduced the survival of colon cancer cells and could be used as a therapeutic tool for colon cancer therapy. PMID: 23733421
    6. These results indicate that the interaction between Hsp90 and eIF3c may play an important role in hepatitis C virus internal ribosome entry site-mediated translation. PMID: 22016036

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    EIF-3 subunit C family
  • 數據庫鏈接:

    HGNC: 3279

    OMIM: 603916

    KEGG: hsa:8663

    STRING: 9606.ENSP00000332604

    UniGene: Hs.567374



主站蜘蛛池模板: 中文字幕无码不卡免费视频| 国产精品无码一本二本三本色| 欧美激情视频一区二区三区免费| 尤物视频在线观看| 亚洲日韩乱码中文字幕| 久久无码喷吹高潮播放不卡| 少妇久久久久久被弄高潮| 四虎影视成人永久免费观看视频 | 国产成人精品亚洲日本在线观看| 国产精品亚洲一区二区三区喷水| 亚洲色老汉av无码专区最| 男女免费观看在线爽爽爽视频| 亚洲色欲色欲www| 久久久久国精品产熟女久色| 香蕉97超级碰碰碰视频| 亚洲熟妇无码av不卡在线播放| 韩国精品一区二区无码视频| 亚洲大乳高潮日本专区| 亚洲麻豆av成本人无码网站| 亚洲午夜成人av电影| 亚洲人成人网站色www| 欧洲女人牲交性开放视频| 亚洲色无码播放| 唐人社导航福利精品| 亚洲第一极品精品无码| 免费毛片在线看片免费丝瓜视频| 国产妇女馒头高清泬20p多| 免费人妻精品一区二区三区 | 日本午夜看x费免| 狠狠色噜噜狠狠狠888米奇| 99精品免费久久久久久久久日本 | 成人午夜电影福利免费| 亚洲第一狼人伊人av| 免费久久人人爽人人爽av| 在线观看免费视频污网站| 无码人妻一区二区三区免费n鬼逝 好爽好湿好硬好大免费视频 | 美国人性欧美xxxx| 爆乳熟妇一区二区三区霸乳| 无码人妻aⅴ一区二区三区玉蒲团 日本三级香港三级人妇三 | 国产成人免费高清直播| a亚洲va欧美va国产综合|