在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

EIF3C Antibody

  • 中文名稱:
    EIF3C兔多克隆抗體
  • 貨號:
    CSB-PA007531GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    EIF3C
  • 別名:
    Cell migration inducing protein 17 antibody; eIF 3c antibody; eIF3 p110 antibody; eIF3-p110 antibody; eIF3c antibody; EIF3C_HUMAN antibody; EIF3CL antibody; EIF3S8 antibody; EIF3S8 protein antibody; Eukaryotic translation initiation factor 3 subunit 8 (110kD) antibody; Eukaryotic translation initiation factor 3 subunit 8 110kDa antibody; Eukaryotic translation initiation factor 3 subunit 8 antibody; Eukaryotic translation initiation factor 3 subunit C antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human EIF3C
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
  • 基因功能參考文獻:
    1. In EIF3C-positive tumors, 32 out of 42 showed significantly higher frequencies of high grade group by immunoreactivity. PMID: 28854163
    2. High eIF3c expression is positively associated with KRAS. PMID: 28231410
    3. These findings suggest that eIF3c is overexpressed in human gliomas and essential for their proliferation and survival. PMID: 25823503
    4. eukaryotic initiation factor 4G (eIF4G) protein binds to eIF3c, -d, and -e to promote mRNA recruitment to the ribosome. PMID: 24092755
    5. Collectively, eIF3c deletion effectively reduced the survival of colon cancer cells and could be used as a therapeutic tool for colon cancer therapy. PMID: 23733421
    6. These results indicate that the interaction between Hsp90 and eIF3c may play an important role in hepatitis C virus internal ribosome entry site-mediated translation. PMID: 22016036

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    EIF-3 subunit C family
  • 數據庫鏈接:

    HGNC: 3279

    OMIM: 603916

    KEGG: hsa:8663

    STRING: 9606.ENSP00000332604

    UniGene: Hs.567374



主站蜘蛛池模板: 性欧美丰满熟妇xxxx性仙踪林| 人妻夜夜爽天天爽三区 | 樱花草视频www日本韩国| 国产午夜精品一区二区三区不卡| 国产一区二区女内射| 免费刺激性视频大片区| 丁香婷婷激情综合俺也去| 亚洲精品宾馆在线精品酒店| 在线播放亚洲人成电影| 成人精品天堂一区二区三区| 国产sm调教视频在线观看| 国产69精品久久久久人妻刘玥| 欧美性色黄大片www喷水| 无码被窝影院午夜看片爽爽jk| 韩国精品视频一区二区在线播放| 伊伊综合在线视频无码| 男人撕开奶罩揉吮奶头视频| 精品国产丝袜自在线拍国语| 国产一卡2卡3卡4卡国色天香| 欧美疯狂xxxxbbbb喷潮| 国产欠欠欠18一区二区| 成人免费无遮挡无码黄漫视频| 人妻avav中文系列久久| 人妻系列无码一区二区三区| 国产成人8x视频网站入口| 国产成人无码区免费内射一片色欲| 99久久精品国产成人综合| 久久99av无色码人妻蜜| 久久久无码精品亚洲日韩按摩 | 国产尤物精品视频| 亚洲国产成人精品福利| 亚洲精品久久国产高清小说| 大胆欧美熟妇xxbbwwbw高潮了| 五级黄高潮片90分钟视频| 综合在线视频精品专区| 亚洲一区二区三区在线网址| 人人妻人人澡人人爽欧美一区双| 小嫩妇好紧好爽再快视频| 粗壮挺进人妻水蜜桃成熟漫画| 在线播放免费播放av片| 婷婷丁香五月中文字幕|