在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Enhancer of rudimentary homolog (ERH)

In Stock
  • 中文名稱:
    Recombinant Human Enhancer of rudimentary homolog (ERH)
  • 貨號:
    CSB-EP007785HUf0
  • 規格:
    ¥1836
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 95% as determined by SDS-PAGE.
  • 生物活性:
    Not Test
  • 基因名:
    ERH
  • Uniprot No.:
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.coli
  • 分子量:
    43.7 kDa
  • 表達區域:
    2-104aa
  • 氨基酸序列
    SHTILLVQPTKRPEGRTYADYESVNECMEGVCKMYEEHLKRMNPNSPSITYDISQLFDFIDDLADLSCLVYRADTQTYQPYNKDWIKEKIYVLLRRQAQQAGK
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    C-terminal GST-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    May have a role in the cell cycle.
  • 基因功能參考文獻:
    1. Data suggest that ERH interacts directly in nucleus with C-terminal Arg-Gly-rich region of SAFB1/SAFB2 and this multimer co-localizes in insoluble nuclear fraction; binding of ERH reverses inhibition exerted by SAFB1/SAFB2 on SRPK1. (ERH = enhancer of rudimentary homolog protein; SAFB = scaffold attachment factor B; SRPK1 = splicing kinase SR protein kinase-1) PMID: 28627136
    2. ERH regulation of RNA processing is needed to ensure faithful DNA replication and repair. PMID: 26100022
    3. REVIEW: recent findings indicate that ERH plays an important role in cell cycle through its mRNA splicing activity and is critically required for genomic stability and cancer cell survival PMID: 24078386
    4. Identification of amino acid residues of ERH required for its recruitment to nuclear speckles and replication foci PMID: 24015320
    5. Evolutionarily conserved protein ERH controls CENP-E mRNA splicing and is required for the survival of KRAS mutant cancer cells. PMID: 23236152
    6. ERH contributes to chromosome alignment at the metaphase plate by localizing CENP-E at kinetochore regions. PMID: 22704934
    7. molecular structure, dimerization and protein-protein interactions PMID: 15794639
    8. ERH may be an important transcription regulator that also functions in the control of cell-cycle progression. PMID: 17444515
    9. interaction with ERH could block the binding of p21(Cip1/Waf1) by Ciz1 in the cell. When ERH and Ciz1 are coexpressed in HeLa cells, Ciz1 recruits ERH to DNA replication foci PMID: 18081865
    10. Enhancer of rudimentary homolog (ERH) overexpression may be implicated in the initiation and/or progression of certain human malignancies. PMID: 18500978

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    E(R) family
  • 組織特異性:
    Expressed in all tissues examined.
  • 數據庫鏈接:

    HGNC: 3447

    OMIM: 601191

    KEGG: hsa:2079

    STRING: 9606.ENSP00000451080

    UniGene: Hs.509791



主站蜘蛛池模板: 日本免费一区二区三区日本| 图片小说视频一区二区| 亚洲一区av无码少妇电影| 国产aⅴ精品一区二区三区尤物| 欧美孕妇xxxx做受欧美88| 国产精品欧美久久久久无广告| 精品一区二区三区四区五区六区| 国产suv精品一区| 国产蝌蚪视频一区二区三区 | 国产精品真实灌醉女在线播放| 国产高清在线精品一区免费| 一本大道久久久久精品嫩草| 成年免费视频黄网站在线观看 | 97精品尹人久久大香线蕉| 揉着我的奶从后面进去视频| 欧美精品国产aⅴ一区二区在线| 国产ae86亚洲福利入口| 亚洲伦无码中文字幕另类| 成人免费毛片aaaaaa片| 久久aⅴ无码av高潮av喷吹| 玩肥熟老妇bbw视频| 成人三级无码视频在线观看| 免费人妻av无码专区| 亚洲成aⅴ人片久青草影院| 97国产在线看片免费人成视频| 99无码熟妇丰满人妻啪啪| 国产午夜伦鲁鲁| 久久综合少妇11p| 男女爽爽无遮挡午夜视频| 无码精品人妻一区二区三区漫画| 天堂俺去俺来也www色官网| 亚洲国产成人无码av在线播放| 一区二区三区无码高清视频| 99精品久久久久久久婷婷| 最近中文字幕免费大全在线| 欧美人妻少妇精品久久黑人| 久久精品免费一区二区| 在线观看日本亚洲一区| 国产av无码精品色午夜| 亚洲狠狠婷婷综合久久| 亚洲色无码国产精品网站可下载|