在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human ERO1-like protein beta (ERO1LB)

  • 中文名稱(chēng):
    人ERO1B重組蛋白
  • 貨號(hào):
    CSB-YP774834HU
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱(chēng):
    人ERO1B重組蛋白
  • 貨號(hào):
    CSB-EP774834HU
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 其他:
  • 中文名稱(chēng):
    人ERO1B重組蛋白
  • 貨號(hào):
    CSB-EP774834HU-B
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱(chēng):
    人ERO1B重組蛋白
  • 貨號(hào):
    CSB-BP774834HU
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱(chēng):
    人ERO1B重組蛋白
  • 貨號(hào):
    CSB-MP774834HU
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Endoplasmic oxidoreductin-1-like protein B; Endoplasmic reticulum oxidoreductin-1-like protein B; ERO1; S. cerevisiae; homolog of; beta; ERO1-L-beta; ERO1-like beta (S. cerevisiae); ERO1-like protein beta; ERO1B_HUMAN; Ero1lb; Oxidoreductin-1-L-beta
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度:
    Full Length of Mature Protein
  • 表達(dá)區(qū)域:
    34-467
  • 氨基酸序列
    QVTGVLD DCLCDIDSID NFNTYKIFPK IKKLQERDYF RYYKVNLKRP CPFWAEDGHC SIKDCHVEPC PESKIPVGIK AGHSNKYLKM ANNTKELEDC EQANKLGAIN STLSNQSKEA FIDWARYDDS RDHFCELDDE RSPAAQYVDL LLNPERYTGY KGTSAWRVWN SIYEENCFKP RSVYRPLNPL APSRGEDDGE SFYTWLEGLC LEKRVFYKLI SGLHASINLH LCANYLLEET WGKPSWGPNI KEFKHRFDPV ETKGEGPRRL KNLYFLYLIE LRALSKVAPY FERSIVDLYT GNAEEDADTK TLLLNIFQDT KSFPMHFDEK SMFAGDKKGA KSLKEEFRLH FKNISRIMDC VGCDKCRLWG KLQTQGLGTA LKILFSEKEI QKLPENSPSK GFQLTRQEIV ALLNAFGRLS TSIRDLQNFK VLLQHSR
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Other protein disulfide isomerase family members can also be reoxidized, but at lower rates compared to P4HB, including PDIA2 (50% of P4HB reoxidation rate), as well as PDIA3, PDIA4, PDIA6 and NXNDC12 (<10%). Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. May be involved in oxidative proinsulin folding in pancreatic cells, hence may play a role in glucose homeostasis.
  • 基因功能參考文獻(xiàn):
    1. This peptide, Ac-VDTTD-AFC, was efficiently cleaved by purified caspase-2 and auto-activating caspase-2 in mammalian cells, and exhibited better selectivity for caspase-2 relative to caspase-3 than reagents that are currently available. PMID: 27919037
    2. GJB2 and ERO1LB are implicated in pancreatic cancer progression and can be used to predict patient survival PMID: 28177904
    3. upregulated in pancreatic neuroendocrine tumors PMID: 26765469
    4. In the present work, it was shown that recombinant human Ero1beta is twice as active as Ero1alpha in enzymatic assays. PMID: 21091435
    5. glutathione limits Ero1-dependent oxidation in the endoplasmic reticulum PMID: 15161913
    6. analysis of Ero1beta tissue distribution and dimerization PMID: 16012172
    7. Ero1alpha and Ero1beta are retained in the endoplasmic reticulum by interactions with PDI and ERp44 PMID: 16677073
    8. the Ero FAD binding domain is critical for conformational stability, allowing Ero proteins to withstand stress conditions that cause client proteins to misfold PMID: 16822866
    9. The lack of correlation between changes in SAT adiponectin gene and protein expression and its circulating levels suggests that adipose tissue synthesis and release of adiponectin are highly regulated pathways. PMID: 18996753

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side. Note=The association with ERP44 may be essential for its retention in the endoplasmic reticulum.
  • 蛋白家族:
    EROs family
  • 組織特異性:
    Highly expressed in the digestive tract, including the duodenum and lower digestive tract. In the stomach, highly expressed in enzyme-producing chief cells (at protein level). In the pancreas, expressed in islets of Langerhans and, at lower levels, in enz
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 14355

    OMIM: 615437

    KEGG: hsa:56605

    STRING: 9606.ENSP00000346635

    UniGene: Hs.558519



主站蜘蛛池模板: 人妻少妇被粗大爽9797pw| 草的我好爽视频| 九九久久精品无码专区| 成在人av抽搐高潮喷水流白浆| 欧美激情猛片xxxⅹ大3| 亚洲精品久久久久午夜aⅴ| 国产成人综合在线视频| 亚洲乱码精品久久久久..| 色一情一乱一伦一区二区三区小说| 免费不卡无码av在线观看| 妺妺窝人体色www看人体| 亚洲乱码精品久久久久..| 日本理论片午午伦夜理片2021 | 中文字幕日韩精品有码视频| 日韩精品人妻系列无码专区| 国产漂亮白嫩美女在线观看| 日韩欧美mv在线观看免费| 中文字幕亚洲综合久久蜜桃| 最近更新中文字幕| 久久精品2021国产| 好吊射视频988gaocom| 国产成人精品一区二区三区无码| 玩弄放荡人妻一区二区三区| 丁香五月缴情在线| 西西人体做爰大胆性自慰| 猫咪www免费人成人入口| 亚洲真人无码永久在线| 午夜国产成人片在线播放| 亚洲五月丁香综合视频| 熟女少妇在线视频播放| 国产精品青青青在线观看| 在线观看特色大片免费视频 | 视频分类 国内精品| 成人免费直播| 色偷偷尼玛图亚洲综合| 一本色道久久88亚洲精品综合| 国产精品亲子乱子伦xxxx裸| 日本理论片午午伦夜理片2021 | 精品熟人妻一区二区三区四区不卡| 日本亚洲欧美在线视观看| 初尝黑人嗷嗷叫中文字幕|