在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human EMILIN-1 (EMILIN1), partial

Recombinant Human EMILIN-1 (EMILIN1), partial

  • 中文名稱：
    人EMILIN1重組蛋白
  • 貨號：
    CSB-YP896753HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人EMILIN1重組蛋白
  • 貨號：
    CSB-EP896753HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人EMILIN1重組蛋白
  • 貨號：
    CSB-EP896753HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人EMILIN1重組蛋白
  • 貨號：
    CSB-BP896753HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人EMILIN1重組蛋白
  • 貨號：
    CSB-MP896753HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    EMILIN1
  • Uniprot No.：
  • 別名：
    Elastin microfibril interface located protein 1; Elastin microfibril interface located protein; Elastin microfibril interface-located protein 1; Elastin microfibril interfacer 1; EMIL1_HUMAN; EMILIN 1; EMILIN; EMILIN-1; Emilin1; gp115
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity.
  • 基因功能參考文獻：
    1. Study discloses a novel mechanism of interaction occurring between the trimeric gC1q domain of EMILIN1 and the alpha4beta1 integrin and determines that the three E933 residues (one from each monomer) are all required for ligand binding. Furthermore, R904 was identified as a synergistic residue for cell adhesion. PMID: 29037761
    2. This study is the first to identify EMILIN-1 and ILK as prospective markers of islet regenerative function in human mesenchymal stem cells. PMID: 27090767
    3. These findings collectively suggest that EMILIN1 may represent a new disease gene associated with an autosomal-dominant connective tissue disorder. PMID: 26462740
    4. Data suggested mechanisms for homo- and hetero-typic EMILINs multimers formation: EMILIN1 or EMILIN2 alone can form trimers and multimers in the absence of each other or they can co-polymerize in a head-to-tail fashion to form hetero-typic multimers. PMID: 25445627
    5. The present findings highlight the peculiar activity of PMN elastase in disabling EMILIN1 suppressor function. PMID: 24513040
    6. All three SNPs in introns 1 and 5 (rs2289360, rs2011616 and rs7424556) of EMILIN1 were in strong pair-wise linkage disequilibrium and were significantly associated with hypertension. PMID: 21753788
    7. Emilin-1 produced by vascular smooth muscle cells acts as a main regulator of resting blood pressure levels by controlling the myogenic response in resistance arteries through TGF-beta. PMID: 22814752
    8. There were significant associations of rs2011616 and rs2304682 polymorphisms in the EMILIN1 gene with hypertension among Japanese. PMID: 22639547
    9. EMILIN-1 may regulate the formation of oxytalan fibers and play a role in their homeostasis. PMID: 20701466
    10. rs2289360, rs2011616, and rs2304682 in the human EMILIN1 gene, as well as the haplotype constructed using rs2536512, rs2011616, and rs17881426, are useful genetic markers of essential hypertension in Japanese men. PMID: 20186130
    11. beta1 Integrin-dependent cell adhesion to this protein is mediated by its gC1q domain PMID: 12456677
    12. NMR assignments for the C-terminal globular domain of EMILIN-1 PMID: 15017143
    13. EMILIN1 interacts with anthrax protective antigen and inhibits toxin action in vitro. EMILIN1 may be a potential target and/or a protein useful for countermeasures against B. anthracis toxin lethality. PMID: 17988845
    14. EMILIN1 is a novel local regulator of lymphangiogenesis PMID: 18411305
    15. EMILIN1 gC1q-alpha4beta1 represents a unique ligand/receptor system, with a requirement for a 3-fold arrangement of the interaction site. PMID: 18463100
    16. Our findings don't support positive association of Emilin1 gene with EH, but the interaction of age and genotype variation of rs3754734 and rs2011616 might increase the risk to hypertension PMID: 19922630

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted, extracellular space, extracellular matrix.
  • 組織特異性：
    Distributed in tissues where resilience and elastic recoil are prominent. Highest levels in the adult small intestine, aorta, lung, uterus, and appendix and in the fetal spleen, kidney, lung, and heart; intermediate expression was detected in adult liver,
  • 數據庫鏈接：

    HGNC: 19880

    OMIM: 130660

    KEGG: hsa:11117

    STRING: 9606.ENSP00000369677

    UniGene: Hs.63348



主站蜘蛛池模板： 人妻大战黑人白浆狂泄| 精品人妻一区二区三区四区| 国产精品538一区二区在线| 国产精品久久久久久成人影院| 插鸡网站在线播放免费观看| 18禁男女污污污午夜网站免费暖暖| 国语对白刺激精品视频| 女人被爽到高潮视频免费国产 | 国产肥白大熟妇bbbb视频| 无码一区二区三区中文字幕 | 粉嫩极品国产在线观看| 久久亚洲国产成人精品无码区| 狠狠躁夜夜躁人人爽超碰97香蕉| 日韩精品一卡2卡三卡4卡| 热の综合热の国产热の潮在线| 裸体丰满白嫩大尺度尤物| 天堂а在线中文在线新版| 一本色道久久综合无码人妻| 日本高清www午色夜com| 日韩亚洲中字无码一区二区三区 | 激情综合色五月六月婷婷| av综合网男人的天堂| 日韩午夜理论片 中文字幕| 性高朝久久久久久久久久| 国产农村熟妇videos| 97夜夜澡人人爽人人喊a| 青青草国产精品欧美成人| 国产啪精品视频网站免| 中文字幕有码无码人妻av蜜桃| 亚洲日韩精品欧美一区二区| 中文精品久久久久人妻| 亚洲精品午夜一区人人爽| 人与性动交aaaabbbb| 日本最大色倩网站www| 中文人妻av久久人妻18| 国产精品jk白丝在线播放| 狠狠色噜噜狠狠狠777米奇888| 中国妇女做爰视频| 波多野结衣网站| 中文字幕在线亚洲日韩6页| 伊人久久大香线蕉成人|