在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

EMILIN1 Antibody

  • 中文名稱:
    EMILIN1兔多克隆抗體
  • 貨號:
    CSB-PA896753LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human ovarian tissue using CSB-PA896753LA01HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) EMILIN1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    EMILIN1
  • 別名:
    Elastin microfibril interface located protein 1 antibody; Elastin microfibril interface located protein antibody; Elastin microfibril interface-located protein 1 antibody; Elastin microfibril interfacer 1 antibody; EMIL1_HUMAN antibody; EMILIN 1 antibody; EMILIN antibody; EMILIN-1 antibody; Emilin1 antibody; gp115 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human EMILIN-1 protein (1-347AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,EMILIN1 Antibody (CSB-PA896753LA01HU),的標記方式是Non-conjugated。對于EMILIN1 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA896753LB01HU EMILIN1 Antibody, HRP conjugated ELISA
    FITC CSB-PA896753LC01HU EMILIN1 Antibody, FITC conjugated
    Biotin CSB-PA896753LD01HU EMILIN1 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity.
  • 基因功能參考文獻:
    1. Study discloses a novel mechanism of interaction occurring between the trimeric gC1q domain of EMILIN1 and the alpha4beta1 integrin and determines that the three E933 residues (one from each monomer) are all required for ligand binding. Furthermore, R904 was identified as a synergistic residue for cell adhesion. PMID: 29037761
    2. This study is the first to identify EMILIN-1 and ILK as prospective markers of islet regenerative function in human mesenchymal stem cells. PMID: 27090767
    3. These findings collectively suggest that EMILIN1 may represent a new disease gene associated with an autosomal-dominant connective tissue disorder. PMID: 26462740
    4. Data suggested mechanisms for homo- and hetero-typic EMILINs multimers formation: EMILIN1 or EMILIN2 alone can form trimers and multimers in the absence of each other or they can co-polymerize in a head-to-tail fashion to form hetero-typic multimers. PMID: 25445627
    5. The present findings highlight the peculiar activity of PMN elastase in disabling EMILIN1 suppressor function. PMID: 24513040
    6. All three SNPs in introns 1 and 5 (rs2289360, rs2011616 and rs7424556) of EMILIN1 were in strong pair-wise linkage disequilibrium and were significantly associated with hypertension. PMID: 21753788
    7. Emilin-1 produced by vascular smooth muscle cells acts as a main regulator of resting blood pressure levels by controlling the myogenic response in resistance arteries through TGF-beta. PMID: 22814752
    8. There were significant associations of rs2011616 and rs2304682 polymorphisms in the EMILIN1 gene with hypertension among Japanese. PMID: 22639547
    9. EMILIN-1 may regulate the formation of oxytalan fibers and play a role in their homeostasis. PMID: 20701466
    10. rs2289360, rs2011616, and rs2304682 in the human EMILIN1 gene, as well as the haplotype constructed using rs2536512, rs2011616, and rs17881426, are useful genetic markers of essential hypertension in Japanese men. PMID: 20186130
    11. beta1 Integrin-dependent cell adhesion to this protein is mediated by its gC1q domain PMID: 12456677
    12. NMR assignments for the C-terminal globular domain of EMILIN-1 PMID: 15017143
    13. EMILIN1 interacts with anthrax protective antigen and inhibits toxin action in vitro. EMILIN1 may be a potential target and/or a protein useful for countermeasures against B. anthracis toxin lethality. PMID: 17988845
    14. EMILIN1 is a novel local regulator of lymphangiogenesis PMID: 18411305
    15. EMILIN1 gC1q-alpha4beta1 represents a unique ligand/receptor system, with a requirement for a 3-fold arrangement of the interaction site. PMID: 18463100
    16. Our findings don't support positive association of Emilin1 gene with EH, but the interaction of age and genotype variation of rs3754734 and rs2011616 might increase the risk to hypertension PMID: 19922630

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted, extracellular space, extracellular matrix.
  • 組織特異性:
    Distributed in tissues where resilience and elastic recoil are prominent. Highest levels in the adult small intestine, aorta, lung, uterus, and appendix and in the fetal spleen, kidney, lung, and heart; intermediate expression was detected in adult liver,
  • 數據庫鏈接:

    HGNC: 19880

    OMIM: 130660

    KEGG: hsa:11117

    STRING: 9606.ENSP00000369677

    UniGene: Hs.63348



主站蜘蛛池模板: 亚洲国产成人片在线观看无码| 偷偷色噜狠狠狠狠的777米奇| 粗了大了 整进去好爽视频| 国产成人免费97在线| 欧洲精品va无码一区二区三区| 精品久久久久久中文字幕202| 亚洲色大成网站www尤物| 国产日产欧产精品精品| 在线人成免费视频69国产| 99国产精品久久久久久久久久久| 特黄特色大片免费播放| 亚洲vs日韩vs欧美vs久久| 日韩精品一卡2卡3卡4卡新区| 粗大黑人巨精大战欧美成人| 国产特级毛片aaaaaa毛片| 午夜精品电影你懂的| 波多野结衣超清无码专区| 久久精品国产99精品国产亚洲性色| 成人免费777777| 玩肥熟老妇bbw视频| 久久国内精品自在自线400部| 影音先锋人妻啪啪av资源网站 | 后入内射国产一区二区| 久久婷婷五月综合色国产香蕉| 无码专区视频精品老司机| 99精品国产一区二区三区不卡 | 亚洲中文有码字幕日本| 亚洲中文字幕无码久久| 人人澡超碰碰97碰碰碰| 人妻丝袜中文无码av影音先锋专区| 久久精品人人爽人人爽| 亚洲国产色播av在线| 大地资源中文第三页| 亚洲最大的成人网站| 免费人成再在线观看视频| 暖暖视频日本| 国产成人av免费观看| 亚洲乱码日产精品bd在| 小罗莉极品一线天在线| 丰满饥渴老女人hd| 亚洲国产成人精品无码区花野真一|