在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

EMILIN1 Antibody, HRP conjugated

  • 中文名稱:
    EMILIN1兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA896753LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) EMILIN1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    EMILIN1
  • 別名:
    Elastin microfibril interface located protein 1 antibody; Elastin microfibril interface located protein antibody; Elastin microfibril interface-located protein 1 antibody; Elastin microfibril interfacer 1 antibody; EMIL1_HUMAN antibody; EMILIN 1 antibody; EMILIN antibody; EMILIN-1 antibody; Emilin1 antibody; gp115 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human EMILIN-1 protein (1-347AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity.
  • 基因功能參考文獻:
    1. Study discloses a novel mechanism of interaction occurring between the trimeric gC1q domain of EMILIN1 and the alpha4beta1 integrin and determines that the three E933 residues (one from each monomer) are all required for ligand binding. Furthermore, R904 was identified as a synergistic residue for cell adhesion. PMID: 29037761
    2. This study is the first to identify EMILIN-1 and ILK as prospective markers of islet regenerative function in human mesenchymal stem cells. PMID: 27090767
    3. These findings collectively suggest that EMILIN1 may represent a new disease gene associated with an autosomal-dominant connective tissue disorder. PMID: 26462740
    4. Data suggested mechanisms for homo- and hetero-typic EMILINs multimers formation: EMILIN1 or EMILIN2 alone can form trimers and multimers in the absence of each other or they can co-polymerize in a head-to-tail fashion to form hetero-typic multimers. PMID: 25445627
    5. The present findings highlight the peculiar activity of PMN elastase in disabling EMILIN1 suppressor function. PMID: 24513040
    6. All three SNPs in introns 1 and 5 (rs2289360, rs2011616 and rs7424556) of EMILIN1 were in strong pair-wise linkage disequilibrium and were significantly associated with hypertension. PMID: 21753788
    7. Emilin-1 produced by vascular smooth muscle cells acts as a main regulator of resting blood pressure levels by controlling the myogenic response in resistance arteries through TGF-beta. PMID: 22814752
    8. There were significant associations of rs2011616 and rs2304682 polymorphisms in the EMILIN1 gene with hypertension among Japanese. PMID: 22639547
    9. EMILIN-1 may regulate the formation of oxytalan fibers and play a role in their homeostasis. PMID: 20701466
    10. rs2289360, rs2011616, and rs2304682 in the human EMILIN1 gene, as well as the haplotype constructed using rs2536512, rs2011616, and rs17881426, are useful genetic markers of essential hypertension in Japanese men. PMID: 20186130
    11. beta1 Integrin-dependent cell adhesion to this protein is mediated by its gC1q domain PMID: 12456677
    12. NMR assignments for the C-terminal globular domain of EMILIN-1 PMID: 15017143
    13. EMILIN1 interacts with anthrax protective antigen and inhibits toxin action in vitro. EMILIN1 may be a potential target and/or a protein useful for countermeasures against B. anthracis toxin lethality. PMID: 17988845
    14. EMILIN1 is a novel local regulator of lymphangiogenesis PMID: 18411305
    15. EMILIN1 gC1q-alpha4beta1 represents a unique ligand/receptor system, with a requirement for a 3-fold arrangement of the interaction site. PMID: 18463100
    16. Our findings don't support positive association of Emilin1 gene with EH, but the interaction of age and genotype variation of rs3754734 and rs2011616 might increase the risk to hypertension PMID: 19922630

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted, extracellular space, extracellular matrix.
  • 組織特異性:
    Distributed in tissues where resilience and elastic recoil are prominent. Highest levels in the adult small intestine, aorta, lung, uterus, and appendix and in the fetal spleen, kidney, lung, and heart; intermediate expression was detected in adult liver,
  • 數據庫鏈接:

    HGNC: 19880

    OMIM: 130660

    KEGG: hsa:11117

    STRING: 9606.ENSP00000369677

    UniGene: Hs.63348



主站蜘蛛池模板: 精品国际久久久久999| 日本熟妇人妻xxxx| 亚洲大尺度无码无码专线一区| 亚洲动漫精品无码av天堂| 久久精品国产99久久无毒不卡| 国产精品∧v在线观看| 成年女人免费视频播放体验区| 亚洲午夜性猛春交xxxx| 伊人婷婷色香五月综合缴缴情| 成人免费乱码大片a毛片| 无码毛片内射白浆视频| 俄罗斯美女真人性做爰| 久久精品国产精油按摩| 国产精品无码翘臀在线看 | 国产精品毛片无遮挡高清| 国产人与禽zoz0性伦多活几年| 国产精品精华液网站| 天堂mv在线mv免费mv香蕉| 亚洲另类欧美在线电影| а天堂中文在线官网在线| 亚洲国产成人久久精品大牛影视| 三级做a全过程在线观看| 久9视频这里只有精品试看| 熟妇人妻中文字幕无码老熟妇| 欧美亚洲色综久久精品国产| 久久精品人妻无码一区二区三区v| 国产一区精选播放022| 一区二区三区内射美女毛片 | 双乳奶水饱满少妇呻吟免费看| 久久av无码精品人妻系列试探| 精品不卡一区二区| 亚洲国产av天码精品果冻传媒| 久青草久青草视频在线观看| 狠狠cao日日穞夜夜穞av| 国产精品99久久精品| 日本久久综合久久鬼色| 一个人在线观看免费视频www| 亚洲精品久久久久久| 97se亚洲综合自在线| 中文字幕av一区| 久久亚洲国产精品成人av秋霞 |