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Recombinant Human DmX-like protein 2 (DMXL2), partial

  • 中文名稱:
    人DMXL2重組蛋白
  • 貨號:
    CSB-YP819469HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人DMXL2重組蛋白
  • 貨號:
    CSB-EP819469HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人DMXL2重組蛋白
  • 貨號:
    CSB-EP819469HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人DMXL2重組蛋白
  • 貨號:
    CSB-BP819469HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人DMXL2重組蛋白
  • 貨號:
    CSB-MP819469HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    DMXL2
  • Uniprot No.:
  • 別名:
    DmX-like protein 2; Dmxl2; DMXL2_HUMAN; KIAA0856; Rabconnectin-3; RC3
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    May serve as a scaffold protein for MADD and RAB3GA on synaptic vesicles. Plays a role in the brain as a key controller of neuronal and endocrine homeostatic processes.
  • 基因功能參考文獻:
    1. Data indicated that the p.Arg2417His variant in DMXL2 is associated with dominant, nonsyndromic hearing loss and suggested an important role of DMXL2 in inner ear function. PMID: 27657680
    2. authors demonstrate that DMXL2 is a transmembrane protein with a potential extra-cellular domain. These findings identify DMXL2 as a novel, functional biomarker for ERalpha positive breast cancer. PMID: 26093085
    3. Haploinsufficiency of Dmxl2, encoding a synaptic protein, causes infertility associated with a loss of GnRH neurons in humans and mice. PMID: 25248098
    4. an important role for Rabconnectin-3 and V-ATPase activity in the Notch signaling pathway in mammalian cells. PMID: 20810660
  • 相關疾病:
    Polyendocrine-polyneuropathy syndrome (PEPNS); Deafness, autosomal dominant, 71 (DFNA71)
  • 亞細胞定位:
    Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle.
  • 數據庫鏈接:

    HGNC: 2938

    OMIM: 612186

    KEGG: hsa:23312

    STRING: 9606.ENSP00000441858

    UniGene: Hs.511386



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