在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Developmental pluripotency-associated protein 3 (DPPA3)

Recombinant Human Developmental pluripotency-associated protein 3 (DPPA3)

  • 中文名稱：
    人DPPA3重組蛋白
  • 貨號(hào)：
    CSB-YP744290HU
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    人DPPA3重組蛋白
  • 貨號(hào)：
    CSB-EP744290HU
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱：
    人DPPA3重組蛋白
  • 貨號(hào)：
    CSB-EP744290HU-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人DPPA3重組蛋白
  • 貨號(hào)：
    CSB-BP744290HU
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人DPPA3重組蛋白
  • 貨號(hào)：
    CSB-MP744290HU
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Compaction associated protein 1; Developmental pluripotency associated 3; Developmental pluripotency associated protein 3; Developmental pluripotency-associated protein 3; Dppa3; DPPA3_HUMAN; PGC7; Stella related protein; Stella-related protein
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度：
    full length protein
  • 表達(dá)區(qū)域：
    1-159
  • 氨基酸序列
    MDPSQFNPTY IPGSPQMLTE ENSRDDSGAS QISSETLIKN LSNLTINASS ESVSPLSEAL LRRESVGAAV LREIEDEWLY SRRGVRTLLS VQREKMARLR YMLLGGVRTH ERRPTNKEPK GVKKESRPFK CPCSFCVSNG WDPSENARIG NQDTKPLQP
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. In zygotes, DNA demethylation occurs selectively in the paternal pronucleus before the first cell division, while the adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this process. Participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at 'Lys-9' (H3K9me2) on maternal genome, and protects maternal genome from TET3-mediated conversion to 5hmC and subsequent DNA demethylation. Does not bind paternal chromatin, which is mainly packed into protamine and does not contain much H3K9me2 mark. Also protects imprinted loci that are marked with H3K9me2 in mature sperm from DNA demethylation in early embryogenesis. May be important for the totipotent/pluripotent states continuing through preimplantation development. Also involved in chromatin condensation in oocytogenesis.
  • 基因功能參考文獻(xiàn)：
    1. Super-enhancers at the Nanog locus differentially regulate neighboring pluripotency-associated genes, in particular, DPPA3. PMID: 27681417
    2. We conclude that heterogeneous population of the HEK293T cells might be easily shifted towards expression of the pluripotency markers by ectopic expression of the SON factors or by growth in serum depleted media. PMID: 27794480
    3. Data suggest enforced expression of Stella into normal cells induces not only global DNA demethylation but also neoplastic transformation and increases metastatic ability; these changes involve altered regulation of neoplastic gene expression. PMID: 26608031
    4. Considering that impaired DNA methylation profiles are associated with various developmental or disease phenomena, Stella may be a powerful tool with which to study the biological effects of global DNA hypomethylation PMID: 25280994
    5. a role for STELLA in facilitating germline and endodermal differentiation of human ES cells PMID: 23457636
    6. human adult tissue-specific transcripts originate via retrotransposition of the pluripotent cell-specific gene, Dppa3 PMID: 16291741
    7. These results demonstrate that PGC7/Stella is indispensable for the maintenance of methylation involved in epigenetic reprogramming after fertilization. PMID: 17143267
    8. In mice, this gene may play a role in oogenesis and primordial germ cell development. PMID: 11900980
    9. In mice, a targeted mutation results in reduced female fertility and may function as a mammalian maternal effect gene. PMID: 14654002
    10. In mice, knockout experiments show this gene may be a maternal factor in cleavage stage embryogenesis. PMID: 15018652

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus. Cytoplasm.
  • 組織特異性：
    Low expression in testis, ovary and thymus. Expressed in embryonic stem and carcinoma cells. Highly expressed in testicular germ cell tumors.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 19199

    OMIM: 608408

    KEGG: hsa:359787

    STRING: 9606.ENSP00000339250

    UniGene: Hs.131358



主站蜘蛛池模板： 蜜桃av抽搐高潮一区二区| 337p日本欧洲亚洲大胆69影院| 影音先锋男人av鲁色资源网| 国产精品久久久久久久久久久久| 四虎一区二区成人免费影院网址| 天天摸夜夜添狠狠添高潮出水 | 女高中生自慰污污网站| 午夜亚洲福利在线老司机| 无码av中文字幕久久专区 | 中文日产乱幕九区无线码| 精品国产日韩亚洲一区| 成在线人视频免费视频| 亚洲国产午夜精品理论片在线播放| 日韩欧无码一区二区三区免费不卡 | 久久综合五月丁香六月丁香| 9re热国产这里只有精品| 国产精品嫩草影院免费观看| 97丨九色丨国产人妻熟女| 国产美女极度色诱视频www| 亚洲欧美日韩成人一区二区三区 | 色综合视频一区二区三区44| 爽爽影院免费观看| 自慰系列无码专区| 秋霞在线观看片无码免费不卡| 女女女女女裸体处开bbb| 成人亚洲精品久久久久软件| 色噜噜亚洲男人的天堂| 高清免费精品国自产拍| 亚洲爆乳无码精品aaa片蜜桃| 国内偷自第一区二区三区| 国产又色又爽又黄的视频在线观看| 欧美人与性动交α欧美精品| 曰本女人与公拘交酡| 无码国产一区二区三区四区| 亚洲日韩欧美在线成人| 欧美高清在线精品一区| 日韩精品人妻系列一区二区三区| 国内精品伊人久久久久妇| 区二区欧美性插b在线视频网站| 欧美丰腴丰满大屁股熟妇| 日韩欧美国产一区精品|