在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. DPPA3 Antibody, HRP conjugated

DPPA3 Antibody, HRP conjugated

  • 中文名稱：
    DPPA3兔多克隆抗體, HRP偶聯(lián)
  • 貨號(hào)：
    CSB-PA744290LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) DPPA3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    Compaction associated protein 1 antibody; Developmental pluripotency associated 3 antibody; Developmental pluripotency associated protein 3 antibody; Developmental pluripotency-associated protein 3 antibody; Dppa3 antibody; DPPA3_HUMAN antibody; PGC7 antibody; Stella related protein antibody; Stella-related protein antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Developmental pluripotency-associated protein 3 protein (1-159AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. In zygotes, DNA demethylation occurs selectively in the paternal pronucleus before the first cell division, while the adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this process. Participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at 'Lys-9' (H3K9me2) on maternal genome, and protects maternal genome from TET3-mediated conversion to 5hmC and subsequent DNA demethylation. Does not bind paternal chromatin, which is mainly packed into protamine and does not contain much H3K9me2 mark. Also protects imprinted loci that are marked with H3K9me2 in mature sperm from DNA demethylation in early embryogenesis. May be important for the totipotent/pluripotent states continuing through preimplantation development. Also involved in chromatin condensation in oocytogenesis.
  • 基因功能參考文獻(xiàn)：
    1. Super-enhancers at the Nanog locus differentially regulate neighboring pluripotency-associated genes, in particular, DPPA3. PMID: 27681417
    2. We conclude that heterogeneous population of the HEK293T cells might be easily shifted towards expression of the pluripotency markers by ectopic expression of the SON factors or by growth in serum depleted media. PMID: 27794480
    3. Data suggest enforced expression of Stella into normal cells induces not only global DNA demethylation but also neoplastic transformation and increases metastatic ability; these changes involve altered regulation of neoplastic gene expression. PMID: 26608031
    4. Considering that impaired DNA methylation profiles are associated with various developmental or disease phenomena, Stella may be a powerful tool with which to study the biological effects of global DNA hypomethylation PMID: 25280994
    5. a role for STELLA in facilitating germline and endodermal differentiation of human ES cells PMID: 23457636
    6. human adult tissue-specific transcripts originate via retrotransposition of the pluripotent cell-specific gene, Dppa3 PMID: 16291741
    7. These results demonstrate that PGC7/Stella is indispensable for the maintenance of methylation involved in epigenetic reprogramming after fertilization. PMID: 17143267
    8. In mice, this gene may play a role in oogenesis and primordial germ cell development. PMID: 11900980
    9. In mice, a targeted mutation results in reduced female fertility and may function as a mammalian maternal effect gene. PMID: 14654002
    10. In mice, knockout experiments show this gene may be a maternal factor in cleavage stage embryogenesis. PMID: 15018652

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus. Cytoplasm.
  • 組織特異性：
    Low expression in testis, ovary and thymus. Expressed in embryonic stem and carcinoma cells. Highly expressed in testicular germ cell tumors.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 19199

    OMIM: 608408

    KEGG: hsa:359787

    STRING: 9606.ENSP00000339250

    UniGene: Hs.131358



主站蜘蛛池模板： 狠狠色成人综合网| 国色天香中文字幕在线视频| 久久久精品中文字幕麻豆发布| 国产欲女高潮正在播放| 亚洲精品一本之道高清乱码 | 无码gogo大胆啪啪艺术| 熟妇熟女乱妇乱女网站| 好紧好爽免费午夜视频| 国产精品va在线播放| 亚洲精品久久| 兔费看少妇性l交大片免费| 亚洲日韩乱码中文字幕| 久久天天躁狠狠躁夜夜2020老熟妇 | 久久人人爽人人爽人人片av高清| 荫道bbwbbb高潮潮喷| 性人久久网av| 中文字幕v亚洲日本在线| 蜜桃视频在线观看免费网址入口| 国产成人a人亚洲精v品无码| 久久精品国产精品亚洲| 国产+日韩+另类+视频一区| 久久精品日日躁夜夜躁| 一边吃奶一边摸做爽视频| 亚洲一区 日韩精品 中文字幕 | 99久久精品费精品国产一区二区 | 亚洲综合色88综合天堂| 无码aⅴ精品一区二区三区浪潮| 无码人妻精品一区二| 超碰国产天天做天天爽| 人妻无码av中文系列久| 男人j进入女人j内部免费网站 | 五月av综合av国产av| 亚洲综合精品伊人久久| 日本japanese丰满多毛| 国产精品亚洲аv久久| 免费人成在线观看视频播放| 久久久这里只有精品10| 亚洲最大无码中文字幕网站| 人妻无码久久一区二区三区免费| 美女裸体自慰在线观看| 女同免费毛片在线播放|