在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Death-inducer obliterator 1 (DIDO1), partial

  • 中文名稱:
    人DIDO1重組蛋白
  • 貨號:
    CSB-YP887120HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人DIDO1重組蛋白
  • 貨號:
    CSB-EP887120HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人DIDO1重組蛋白
  • 貨號:
    CSB-EP887120HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人DIDO1重組蛋白
  • 貨號:
    CSB-BP887120HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人DIDO1重組蛋白
  • 貨號:
    CSB-MP887120HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    DIDO1
  • Uniprot No.:
  • 別名:
    DIDO1; C20orf158; DATF1; KIAA0333Death-inducer obliterator 1; DIO-1; hDido1; Death-associated transcription factor 1; DATF-1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Putative transcription factor, weakly pro-apoptotic when overexpressed. Tumor suppressor. Required for early embryonic stem cell development.; Displaces isoform 4 at the onset of differentiation, required for repression of stemness genes.
  • 基因功能參考文獻:
    1. Results identified a novel pH-dependent mechanism by which epigenetic reader, the PHD fingers of DIDO, recognize the histone mark H3K4me3. The pH-sensing ability might be necessary for normal biological processes and those characterized by altered cellular pH. PMID: 28919441
    2. evaluated the Death Inducer-Obliterator (DIDO) (variants DIDO 1, 2 and 3) levels in CML, PV, ET and PMF patients. Our data reported the DIDO 1, 2 and 3 differential expressions in Myeloproliferative Neoplasms. PMID: 27282563
    3. Dido1 induces the expression of Integrin alphaV, thereby promoting the attachment, migration, invasion and apoptosis resistance of melanoma cells. PMID: 22469980
    4. Data show that CSE1L, DIDO1 and RBM39 mRNA expression levels correlated with chromosome 20q DNA copy number status. PMID: 22711543
    5. Gambogic acid induces the apoptosis of Raji cells through DIO-1 upregulation, nuclear translocation, Bcl-xL downregulation and caspase 3 activation. PMID: 19236754
    6. Data suggest that Dido might be one of the tumor suppressor genes at chromosome 20q and that the Dido-targeted mouse may be a suitable model for studying myeloproliferative diseases and myelodysplastic syndromes. PMID: 16127461
    7. Dido3, the largest splice variant of the Dido gene, is a centrosome-associated protein whose disruption leads to supernumerary centrosomes, failure to maintain cellular mitotic arrest, and early degradation of the mitotic checkpoint protein BubR1. PMID: 17299043
    8. Gambogic acid induces DIDO1-mediated apoptosis in Jurkat T cells. PMID: 18298900

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle.
  • 組織特異性:
    Ubiquitous.
  • 數據庫鏈接:

    HGNC: 2680

    OMIM: 604140

    KEGG: hsa:11083

    STRING: 9606.ENSP00000266070

    UniGene: Hs.517172



主站蜘蛛池模板: 欧美老肥熟妇多毛xxxxx| 在线观看国产成人av天堂| 精品无人区码一码二码三码区别| 国产成+人欧美+综合在线观看| 国产亚洲精品久久久久的角色| 高潮毛片又色又爽免费| 九个美女露脸撒尿嘘嘘视频| 同性女女黄h片在线播放| 最新精品国偷自产在线美女足| 国产无遮挡裸体免费视频在线观看| 男女做爰猛烈叫床视频免费| 国产婷婷色一区二区三区在线| 免费看美女部位隐私网站| 国产美女精品视频线播放| 国产美女在线精品免费观看网址| 中文字幕无码人妻少妇免费| 精品午夜国产福利观看| 高潮迭起av乳颜射后入| 99久久婷婷国产综合精品青草免费 | 少妇无码一区二区三区免费| 又粗又大又硬又长又爽| 中文无码字幕中文有码字幕| 蜜臀少妇人妻在线| 成人免费无码大片a毛片| 亚洲国产美女精品久久久久∴| 久久久久久无码日韩欧美| 丰满人妻被黑人连续中出| 国产成人麻豆亚洲综合无码精品| 98色婷婷在线| 性按摩无码中文| 亚洲日韩久久综合中文字幕| 国产肉体xxxx裸体137大胆 | 隔壁人妻被水电工征服| 成人乱码一区二区三区av| 亚洲一区二区三区香蕉| 伊人久久大香线蕉av综合| 国产在线拍揄自揄拍免费下载| 毛片无码一区二区三区a片视频| 亚洲gv天堂gv无码男同| 中文字幕va一区二区三区| 极品尤物一区二区三区|