在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DIDO1 Antibody

  • 中文名稱:
    DIDO1兔多克隆抗體
  • 貨號:
    CSB-PA564510
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA564510(DIDO1 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA564510(DIDO1 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    DIDO1
  • 別名:
    DIDO1 antibody; C20orf158 antibody; DATF1 antibody; KIAA0333Death-inducer obliterator 1 antibody; DIO-1 antibody; hDido1 antibody; Death-associated transcription factor 1 antibody; DATF-1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Fusion protein of Human DIDO1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Putative transcription factor, weakly pro-apoptotic when overexpressed. Tumor suppressor. Required for early embryonic stem cell development.; Displaces isoform 4 at the onset of differentiation, required for repression of stemness genes.
  • 基因功能參考文獻:
    1. Results identified a novel pH-dependent mechanism by which epigenetic reader, the PHD fingers of DIDO, recognize the histone mark H3K4me3. The pH-sensing ability might be necessary for normal biological processes and those characterized by altered cellular pH. PMID: 28919441
    2. evaluated the Death Inducer-Obliterator (DIDO) (variants DIDO 1, 2 and 3) levels in CML, PV, ET and PMF patients. Our data reported the DIDO 1, 2 and 3 differential expressions in Myeloproliferative Neoplasms. PMID: 27282563
    3. Dido1 induces the expression of Integrin alphaV, thereby promoting the attachment, migration, invasion and apoptosis resistance of melanoma cells. PMID: 22469980
    4. Data show that CSE1L, DIDO1 and RBM39 mRNA expression levels correlated with chromosome 20q DNA copy number status. PMID: 22711543
    5. Gambogic acid induces the apoptosis of Raji cells through DIO-1 upregulation, nuclear translocation, Bcl-xL downregulation and caspase 3 activation. PMID: 19236754
    6. Data suggest that Dido might be one of the tumor suppressor genes at chromosome 20q and that the Dido-targeted mouse may be a suitable model for studying myeloproliferative diseases and myelodysplastic syndromes. PMID: 16127461
    7. Dido3, the largest splice variant of the Dido gene, is a centrosome-associated protein whose disruption leads to supernumerary centrosomes, failure to maintain cellular mitotic arrest, and early degradation of the mitotic checkpoint protein BubR1. PMID: 17299043
    8. Gambogic acid induces DIDO1-mediated apoptosis in Jurkat T cells. PMID: 18298900

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle.
  • 組織特異性:
    Ubiquitous.
  • 數據庫鏈接:

    HGNC: 2680

    OMIM: 604140

    KEGG: hsa:11083

    STRING: 9606.ENSP00000266070

    UniGene: Hs.517172



主站蜘蛛池模板: 狠狠色噜噜狠狠狠777米奇小说| 在线视频 亚太 国产 欧美 一区二区| 欧洲免费无线码在线一区| 午夜好爽好舒服免费视频| 精品午夜中文字幕熟女人妻在线 | 日本乱码伦午夜福利在线| 免费特级黄毛片| 日本一本二本三区免费| 午夜免费福利小电影| 青青草无码伊人久久| 久久久女人与动物群交毛片| 狠狠噜天天噜日日噜视频麻豆| 日韩人妻一区二区三区蜜桃视频| 伊人色综合久久天天五月婷| 中文午夜乱理片无码| 久久青草成人综合网站| 四虎成人精品永久网站| 国产高颜值大学生情侣酒店| 青娱乐极品视觉盛宴国产视频| 欧洲日韩亚洲无线在码| 性一交一乱一伦一| 国产日产精品一区二区三区四区的特点| 少妇高潮毛片免费看| 国产av精国产传媒| 国模国产精品嫩模大尺度视频| 亚洲午夜高清国产拍| 欧美丰满熟妇xxxx性ppx人交| 亚洲精品92内射| 亚洲人成自拍网站在线观看| 最激烈的床震娇喘视频出水| 久久婷婷成人综合色综合| 中国国语毛片免费观看视频| 亚洲成年网站青青草原| 国产成人综合一区人人| 玩两个丰满老熟女| 美女黄18以下禁止观看| 电影内射视频免费观看| 四虎影视永久免费观看在线| 性色欲网站人妻丰满中文久久不卡 | 国产精品无码av在线一区| 中文字幕av无码一二三区电影|