在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DIDO1 Antibody

  • 中文名稱:
    DIDO1兔多克隆抗體
  • 貨號:
    CSB-PA887120ESR1HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA887120ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA887120ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA887120ESR1HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) DIDO1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    DIDO1
  • 別名:
    DIDO1 antibody; C20orf158 antibody; DATF1 antibody; KIAA0333Death-inducer obliterator 1 antibody; DIO-1 antibody; hDido1 antibody; Death-associated transcription factor 1 antibody; DATF-1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Death-inducer obliterator 1 protein (1-300AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Putative transcription factor, weakly pro-apoptotic when overexpressed. Tumor suppressor. Required for early embryonic stem cell development.; Displaces isoform 4 at the onset of differentiation, required for repression of stemness genes.
  • 基因功能參考文獻:
    1. Results identified a novel pH-dependent mechanism by which epigenetic reader, the PHD fingers of DIDO, recognize the histone mark H3K4me3. The pH-sensing ability might be necessary for normal biological processes and those characterized by altered cellular pH. PMID: 28919441
    2. evaluated the Death Inducer-Obliterator (DIDO) (variants DIDO 1, 2 and 3) levels in CML, PV, ET and PMF patients. Our data reported the DIDO 1, 2 and 3 differential expressions in Myeloproliferative Neoplasms. PMID: 27282563
    3. Dido1 induces the expression of Integrin alphaV, thereby promoting the attachment, migration, invasion and apoptosis resistance of melanoma cells. PMID: 22469980
    4. Data show that CSE1L, DIDO1 and RBM39 mRNA expression levels correlated with chromosome 20q DNA copy number status. PMID: 22711543
    5. Gambogic acid induces the apoptosis of Raji cells through DIO-1 upregulation, nuclear translocation, Bcl-xL downregulation and caspase 3 activation. PMID: 19236754
    6. Data suggest that Dido might be one of the tumor suppressor genes at chromosome 20q and that the Dido-targeted mouse may be a suitable model for studying myeloproliferative diseases and myelodysplastic syndromes. PMID: 16127461
    7. Dido3, the largest splice variant of the Dido gene, is a centrosome-associated protein whose disruption leads to supernumerary centrosomes, failure to maintain cellular mitotic arrest, and early degradation of the mitotic checkpoint protein BubR1. PMID: 17299043
    8. Gambogic acid induces DIDO1-mediated apoptosis in Jurkat T cells. PMID: 18298900

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle.
  • 組織特異性:
    Ubiquitous.
  • 數據庫鏈接:

    HGNC: 2680

    OMIM: 604140

    KEGG: hsa:11083

    STRING: 9606.ENSP00000266070

    UniGene: Hs.517172



主站蜘蛛池模板: 撕开奶罩揉吮奶头视频| 精品国产一区二区三区国产区| 欧美丰满大爆乳波霸奶水多| 特级西西人体444www高清大胆 | 国产精品亚韩精品无码a在线 | 少妇人妻偷人精品无码视频新浪| 国产日韩在线时看高清视频| 国产av国片偷人妻麻豆| 亚洲综合色区另类小说 | 日韩精品无码一区二区三区视频| 久久se精品一区二区三区| 开心婷婷五月激情综合社区| 美女又黄又免费的视频| 上司揉捏人妻丰满双乳电影| 国产午夜亚洲精品国产成人| 欧美精品一区二区黄a片| h肉动漫无码无修6080动漫网| 国产激情久久久久影院小草| 亚洲欧洲综合有码无码| 无码国产成人午夜电影在线观看| 人妻少妇精品无码专区二区| 久久综合九色综合欧美婷婷| 少妇极品熟妇人妻200片| 狠狠躁天天躁中文字幕| 少妇无套内谢久久久久| 欧美人与禽zozzo性伦交| 日本污ww视频网站| 一卡二卡三卡视频| 国产精品最新免费视频| 亚洲欧洲美洲在线观看| 综合网日日天干夜夜久久| 久久人人做人人妻人人玩精品hd| 国产精品99久久免费观看| 狠狠综合久久综合88亚洲| 人妻 日韩精品 中文字幕| 中文无码精品a∨在线观看| 三级网站视频在在线播放| 蜜臀av在线播放| 性色a∨人人爽网站hdkp885| 欧洲国产精品无码专区影院| 成熟丰满熟妇高潮xxxxx|