在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Crossover junction endonuclease EME1 (EME1)

  • 中文名稱:
    人EME1重組蛋白
  • 貨號:
    CSB-EP856897HU
  • 規(guī)格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    EME1
  • Uniprot No.:
  • 別名:
    6820428D13; Crossover junction endonuclease EME1; EC 3.1.22.-; EME1; Eme1 essential meiotic endonuclease 1 homolog 1 (S. pombe); EME1; S. pombe; homolog of; 1; EME1_HUMAN; essential meiotic endonuclease 1 homolog 1 (S pombe); Essential Meiotic Endonuclease 1 Homolog 1; essential meiotic endonuclease 1 homolog 2; Essential meiotic endonuclease 1; S. pombe; homolog of; 1; FLJ31364; hMMS4; homolog of yeast EME1 endonuclease; MGC106543; MMS4 ; MMS4 homolog; MMS4L
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Isoform 2
  • 來源:
    E.coli
  • 分子量:
    80.8kDa
  • 表達區(qū)域:
    1-583aa
  • 氨基酸序列
    MALKKSSPSLDSGDSDSEELPTFAFLKKEPSSTKRRQPEREEKIVVVDISDCEASCPPAPELFSPPVPEIAETVTQTQPVRLLSSESEDEEEFIPLAQRLTCKFLTHKQLSPEDSSSPVKSVLDHQNNEGASCDWKKPFPKIPEVPLHDTPERSAADNKDLILDPCCQLPAYLSTCPGQSSSLAVTKTNSDILPPQKKTKPSQKVQGRGSHGCRQQRQARQKESTLRRQERKNAALVTRMKAQRPEECLKHIIVVLDPVLLQMEGGGQLLGALQTMECRCVIEAQAVPCSVTWRRRAGPSEDREDWVEEPTVLVLLRAEAFVSMIDNGKQGSLDSTMKGKETLQGFVTDITAKTAGKALSLVIVDQEKCFSLELLFFDFLPCTSAQNPPRRGKQGANKQTKKQQQRQPEASIGSMVSRVDAEEALVDLQLHTEAQAQIVQSWKELADFTCAFTKAVAEAPFKKLRDETTFSFCLESDWAGGVKVDLAGRGLALVWRRQIQQLNRVSLEMASAVVNAYPSPQLLVQAYQQCFSDKERQNLLADIQVRRGEGVTSTSRRIGPELSRRIYLQMTTLQPHLSLDSAD
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-SUMO-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.
  • 基因功能參考文獻:
    1. The data suggest that subnuclear relocalization is relevant for the function of Mus81-Mms4 complex in response to DNA damage and, probably, of the endonucleases that colocalize with it. PMID: 28813668
    2. EME-1 deficiency affects cell cycle progression and promotes DNA rereplication. PMID: 16456034
    3. Low Eme1 levels were more sensitive to the drug than tumors with high levels. PMID: 19267403
  • 亞細胞定位:
    Nucleus, nucleolus. Note=Recruited to regions of DNA damage in S-phase cells.
  • 蛋白家族:
    EME1/MMS4 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 24965

    OMIM: 610885

    KEGG: hsa:146956

    STRING: 9606.ENSP00000376952

    UniGene: Hs.514330



主站蜘蛛池模板: 久久亚洲精品成人av无码网站 | 亚洲欧美不卡高清在线| 毛片免费全部播放无码| 国产精品永久免费| 亚洲精品日本一区二区三区| 少妇呻吟白浆高潮啪啪69| 欧美性猛交久久久乱大交小说| 国产乱xxxxx97国语对白| 亚洲aⅴ综合色区无码一区| 一二三四观看视频社区在线 | 播放灌醉水嫩大学生国内精品 | 精品无码人妻一区二区三区品 | 男女高潮喷水在线观看| 少妇人妻真实偷人精品视频| 小sao货水好多真紧h无码视频 | 亚洲综合日韩久久成人av| 天堂av无码av在线a√| 1000部拍拍拍18勿入免费视频下载| 免费的很黄很污的视频| 久久无码人妻国产一区二区| √最新版天堂资源网在线下载| 黑人巨大精品欧美黑寡妇| 成在人av抽搐高潮喷水流白浆| 午夜爱爱免费视频体验区| 精品综合久久久久久8888 | 久久久久精品无码一区二区三区| 国产乱码一区二区三区爽爽爽| 影音先锋女人av鲁色资源网久久| 99久久久无码国产精品试看| 亚洲制服丝中文字幕| 被黑人猛躁10次高潮视频| 欧美日韩一区二区三区视频播放| 色综合欧美亚洲国产| 中文字幕韩国三级理论| 无遮挡裸体免费视频尤物 | 亚洲成av大片大片在线播放| 久久久久国产精品人妻aⅴ果冻| 色欲av永久无码精品无码蜜桃| 亚洲第一无码专区天堂| 国产成年女人毛片80s网站| 国产女人高潮叫床视频|