在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Cortistatin (CORT)

  • 中文名稱:
    Recombinant Human Cortistatin(CORT)
  • 貨號:
    CSB-YP005821HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human Cortistatin(CORT)
  • 貨號:
    CSB-EP005821HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human Cortistatin(CORT)
  • 貨號:
    CSB-EP005821HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human Cortistatin(CORT)
  • 貨號:
    CSB-BP005821HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human Cortistatin(CORT)
  • 貨號:
    CSB-MP005821HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    CORT
  • Uniprot No.:
  • 別名:
    CORT; UNQ307/PRO350Cortistatin [Cleaved into: Cortistatin-29; Cortistatin-17]
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Cytoplasmic domain
  • 表達區域:
    77-105
  • 氨基酸序列
    QEGA PPQQSARRDR MPCRNFFWKT FSSCK
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Binds to all human somatostatin receptor (SSTR) subtypes. It also inhibits cAMP production induced by forskolin through SSTRs.
  • 基因功能參考文獻:
    1. Patients with newly diagnosed type 2 diabetes mellitus had lower plasma levels of vortistatin (CST) than healthy controls, and plasma CST was associated with glucose metabolism and insulin resistance. PMID: 28526556
    2. There is a relationship between plamsa CST and BCKDK in sepsis patients. PMID: 27773658
    3. Cortistatin emerges as a natural endogenous regulator of smooth muscle cells under pathological conditions and an attractive candidate for the pharmacological management of vascular diseases that course with neointimal lesion formation. PMID: 23595952
    4. Identifies post-translational cleavage products of the homologous rat protein. PMID: 10461921
    5. The cortistatin expression in the temporal lobe of Alzheimer's disease patients is decressed. PMID: 20164562
    6. Endocrine activities of cortistatin-14 and its interaction with GHRH and ghrelin in humans. PMID: 12161511
    7. first extensive study demonstrating that lymphoid tissues and immune cells express different levels of CST mRNA and that its expression can be regulated; hypothesize a role as an endogenous ligand of at least the sst2 receptor in the immune system PMID: 12519865
    8. study demonstrates for the first time a selective and inducible expression of the recently discovered cortistatin, as well as somatostatin receptor 2, in human monocyte-derived cells PMID: 12684217
    9. cortistatin-14 shown to be a high affinity ligand for G protein coupled receptor MrgX2 which is expressed in dorsal root ganglion PMID: 12915402
    10. Cortistatin plays a role in the auto/paracrine regulation of the endocrine pancreas PMID: 14669820
    11. Intravitreous somatostatin-like immunoreactivity deficit occurs in ptients with proliferative diabetic retinopathy. PMID: 16043736
    12. Human immune cells produce CST, whereas macrophage lineage and activated endothelium express sst2, and human lymphocytes express sst3. The human thymus expresses sst1, 2, 3, MrgX2 and almost all immune cells express GHS-R. [review] PMID: 18450367
    13. A lower expression of CST exists in diabetic retinas and it is associated with retinal neurodegeneration. PMID: 18709137

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Somatostatin family
  • 組織特異性:
    Expressed in a subset of GABAergic cells in the cortex and hippocampus.
  • 數據庫鏈接:

    HGNC: 2257

    OMIM: 602784

    KEGG: hsa:1325

    STRING: 9606.ENSP00000366248

    UniGene: Hs.412311



主站蜘蛛池模板: 亚洲不卡中文字幕无码| 国产香港明星裸体xxxx视频| 精品人妻伦九区久久aaa片69| 丝袜自慰一区二区三区| 国产在线码观看超清无码视频 | 69堂人成无码免费视频果冻传媒 | 爆乳熟妇一区二区三区| 亚洲色大成网站www永久麻豆 | 亚洲欧美午夜理论电影在线观看 | 又粗又黑又大的吊av| 性生交大全免费看| 日韩精品一卡2卡三卡4卡| 韩国19禁主播深夜福利视频| 日韩视频 中文字幕 视频一区| 久久国产精品久久精品国产| 亚洲成a人片在线观看中文| 四虎一区二区成人免费影院网址| 日日摸夜夜摸狠狠摸婷婷| 亚洲国产桃花岛一区二区| 欧美又粗又大xxxxbbbb疯狂| 成人精品视频一区二区三区尤物| 亚洲亚洲熟妇色l图片20p| 久久狼人大香伊蕉国产| 国产成人毛片在线视频| 亚洲精品国产精品国自产观看| 无码少妇一区二区三区芒果| 免费看国产精品3a黄的视频| 国产一区二区三区不卡在线看| 草草地址线路①屁屁影院成人 | 欧美牲交a欧美牲交aⅴ免费真| 人妻少妇heyzo无码专区| 国产精品无打码在线播放| 精品成人毛片一区二区| 无码人妻丰满熟妇啪啪欧美 | 免费能直接看黄的视频| av片在线播放| 韩国美女视频黄是免费| 亚洲vav在线男人的天堂| 成人免费午夜无码视频| 国精产品999国精产品官网| 亚洲国产精品久久网午夜|