在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Complement factor H-related protein 4 (CFHR4)

Recombinant Human Complement factor H-related protein 4 (CFHR4)

  • 中文名稱：
    Recombinant Human Complement factor H-related protein 4(CFHR4)
  • 貨號：
    CSB-YP838769HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Complement factor H-related protein 4(CFHR4)
  • 貨號：
    CSB-EP838769HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Complement factor H-related protein 4(CFHR4)
  • 貨號：
    CSB-EP838769HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Complement factor H-related protein 4(CFHR4)
  • 貨號：
    CSB-BP838769HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Complement factor H-related protein 4(CFHR4)
  • 貨號：
    CSB-MP838769HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    CFHR4
  • Uniprot No.：
  • 別名：
    CFHR4; CFHL4; FHR4Complement factor H-related protein 4; FHR-4
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    20-331
  • 氨基酸序列
    E VKPCDFPEIQ HGGLYYKSLR RLYFPAAAGQ SYSYYCDQNF VTPSGSYWDY IHCTQDGWSP TVPCLRTCSK SDIEIENGFI SESSSIYILN KEIQYKCKPG YATADGNSSG SITCLQNGWS AQPICIKFCD MPVFENSRAK SNGMRFKLHD TLDYECYDGY EISYGNTTGS IVCGEDGWSH FPTCYNSSEK CGPPPPISNG DTTSFLLKVY VPQSRVEYQC QSYYELQGSN YVTCSNGEWS EPPRCIHPCI ITEENMNKNN IQLKGKSDIK YYAKTGDTIE FMCKLGYNAN TSVLSFQAVC REGIVEYPRC E
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Involved in complement regulation. Can associate with lipoproteins and may play a role in lipid metabolism.
  • 基因功能參考文獻：
    1. Next-generation sequencing of the CFH region identified putatively functional variants (missense, splice site and indel) on the four common haplotypes. We found no expression of any of the five CFH-related genes in the retina or RPE/Choroid/Sclera, in contrast to the liver, which is the main source of the circulating proteins. [CFHR4] PMID: 27196323
    2. Studies indicate that complement factor H-related proteins (FHR1-5) may enhance complement activation, with important implications for the role of these proteins in disease. PMID: 25979655
    3. Factor H-related protein 4 activates complement by serving as a platform for the assembly of alternative pathway C3 convertase via its interaction with C3b protein PMID: 22518841
    4. Systemic lupus erythematosus were detected in European Americans and African Americans, which could be attributed to an intronic complement regulator factor H (CFH) single nucleotide polymorphism (SNP) and an intergenic SNP between CFHR1 and CFHR4. PMID: 21637784
    5. These data reveal the molecular basis of the specific interaction of CFHR4 with native CRP and suggest a role for CFHR4 in enhancing opsonization via CRP binding. PMID: 20042240
    6. Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndrome. PMID: 19861685
    7. FHR-4A is a new Factor H-related protein with a unique domain composition, that is an internal duplication of four CCP domains FHR-4A provides the first evidence for alternative splicing among Factor H-related genes. PMID: 15562282
    8. These data identify CFHR4 as a novel ligand for native CRP, and suggest a role for CFHR4 in opsonization of necrotic cells. PMID: 19084272

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted.
  • 組織特異性：
    Expressed by the liver and secreted in plasma.
  • 數據庫鏈接：

    HGNC: 16979

    OMIM: 605337

    KEGG: hsa:10877

    STRING: 9606.ENSP00000356386

    UniGene: Hs.710100



主站蜘蛛池模板： 国产亚洲精品精品国产亚洲综合| 亚洲深深色噜噜狠狠网站| 无人区一码卡二卡三乱码| 丰满少妇69激情啪啪无| 国产激情久久久久影院老熟女免费| 99国产欧美另类久久久精品| 视频二区丝袜国产欧美日韩| 亚洲永久无码7777kkk| 亚洲人成人网站色www| 免费夫妻生活片av| 大香网伊人久久综合网2018| 国产suv精品一区二区| 精品一区二区三区在线观看视频| 久久人妻国产精品| 亚洲乱码在线卡一卡二卡新区| 欧洲精品99毛片免费高清观看 | 天堂网www天堂资源网| 国产成人毛片在线视频| 免费观看羞羞视频网站| 久久天天躁夜夜躁狠狠i女人| 亚洲无线码中文字幕在线| 国产色综合天天综合网| 国产又大又粗又爽的毛片| 亚洲龙腾成小说人网| 日本丰满人妻xxxxxhd| 国产精品无码久久av| 少妇高潮太爽了在线观看| 国产成人av乱码免费观看| 一本久道中文无码字幕av| 免费无码不卡视频在线观看| 亚洲另类欧美小说图片区| 老子影院无码午夜伦不卡| 亚洲精品蜜夜内射| 中文字幕人妻无码专区| 欧美成人高清视频a在线看| 欧美人与动牲猛交a欧美精品 | 亚洲成_人网站图片| 西西人体www大胆高清视频| 男男gv白嫩小受gv在线播放| 成人免费大片黄在线观看com| 影视先锋av资源噜噜|