在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Carnitine O-acetyltransferase (CRAT)

  • 中文名稱:
    Recombinant Human Carnitine O-acetyltransferase(CRAT)
  • 貨號:
    CSB-YP005940HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human Carnitine O-acetyltransferase(CRAT)
  • 貨號:
    CSB-EP005940HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human Carnitine O-acetyltransferase(CRAT)
  • 貨號:
    CSB-EP005940HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human Carnitine O-acetyltransferase(CRAT)
  • 貨號:
    CSB-BP005940HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human Carnitine O-acetyltransferase(CRAT)
  • 貨號:
    CSB-MP005940HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    CRAT
  • Uniprot No.:
  • 別名:
    CACP_HUMAN; Carnitine acetylase; Carnitine acetyltransferase; Carnitine O acetyltransferase; Carnitine O-acetyltransferase; CAT; CAT1; CrAT
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-626
  • 氨基酸序列
    MLAFAARTVV KPLGFLKPFS LMKASSRFKA HQDALPRLPV PPLQQSLDHY LKALQPIVSE EEWAHTKQLV DEFQASGGVG ERLQKGLERR ARKTENWLSE WWLKTAYLQY RQPVVIYSSP GVMLPKQDFV DLQGQLRFAA KLIEGVLDFK VMIDNETLPV EYLGGKPLCM NQYYQILSSC RVPGPKQDTV SNFSKTKKPP THITVVHNYQ FFELDVYHSD GTPLTADQIF VQLEKIWNSS LQTNKEPVGI LTSNHRNSWA KAYNTLIKDK VNRDSVRSIQ KSIFTVCLDA TMPRVSEDVY RSHVAGQMLH GGGSRLNSGN RWFDKTLQFI VAEDGSCGLV YEHAAAEGPP IVTLLDYVIE YTKKPELVRS PLVPLPMPKK LRFNITPEIK SDIEKAKQNL SIMIQDLDIT VMVFHHFGKD FPKSEKLSPD AFIQMALQLA YYRIYGQACA TYESASLRMF HLGRTDTIRS ASMDSLTFVK AMDDSSVTEH QKVELLRKAV QAHRGYTDRA IRGEAFDRHL LGLKLQAIED LVSMPDIFMD TSYAIAMHFH LSTSQVPAKT DCVMFFGPVV PDGYGVCYNP MEAHINFSLS AYNSCAETNA ARLAHYLEKA LLDMRALLQS HPRAKL
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Catalyzes the reversible transfer of acyl groups from carnitine to coenzyme A (CoA) and regulates the acyl-CoA/CoA ratio. Also plays a crucial role in the transport of fatty acids for beta-oxidation. Responsible for the synthesis of short- and branched-chain acylcarnitines. Active towards some branched-chain amino acid oxidation pathway (BCAAO) intermediates. Trans-2-enoyl-CoAs and 2-methylacyl-CoAs are poor substrates.
  • 基因功能參考文獻:
    1. CrAT turned out to be active towards some but not all the BCAAO intermediates tested and no activity was found with dicarboxylic acyl-CoA esters. PMID: 23485643
    2. the purification, crystallization and preliminary X-ray crystallographic studies of human carnitine acetyltransferase are reported PMID: 12077440
    3. The structure and reactions of this enzyme are examined. PMID: 12562770
    4. structure of a binary complex of human peroxisomal carnitine acetyltransferase and the substrate l-carnitine, refined to a resolution of 1.8; site-directed mutagenesis and kinetic characterization PMID: 15099582
    5. Data show that CrAT overexpression in primary human skeletal myocytes increased glucose uptake and attenuated lipid-induced suppression of glucose oxidation. PMID: 19553674
    6. Human CPT1A, CPT1B, CPT2, CROT and CRAT are known to encode active carnitine acyltransferases. Earlier pfam annotations refer to the non-existing compound CARNITATE. In 2000 this has been changed to CARNITINE. PMID: 11001805

    顯示更多

    收起更多

  • 亞細胞定位:
    Endoplasmic reticulum. Peroxisome. Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.; [Isoform 1]: Mitochondrion.; [Isoform 2]: Peroxisome.
  • 蛋白家族:
    Carnitine/choline acetyltransferase family
  • 組織特異性:
    Mostly in skeletal muscle, less in heart, liver and pancreas, only weakly detectable in brain, placenta, lung and kidney.
  • 數據庫鏈接:

    HGNC: 2342

    OMIM: 600184

    STRING: 9606.ENSP00000315013

    UniGene: Hs.12068



主站蜘蛛池模板: 在线观看肉片av网站免费| 韩国无码色视频在线观看| 国产精品日本亚洲欧美| 粉色午夜视频| 精品人妻伦一二三区久久| 国产亚洲产品影视在线产品| 波多野结av在线无码中文| 国产精品无码无卡在线播放| 精品福利视频一区二区三区| 亚洲中文字幕在线第二页| 99精品国产福利一区二区| 四虎影视在线观看2413| 欧美最猛性xxxxx免费| 在线精品视频一区二区| 国产精品亚洲二区在线看| 午夜人妻久久久久久久久| 欧美性生交大片免费看| 精品午夜福利在线视在亚洲| 白丝爆浆18禁一区二区三区 | 国产午夜鲁丝无码拍拍| 伊人久久大香线蕉综合bd高清| 久青青视频在线观看久| 极品熟妇大蝴蝶20p| 人妻中文字幕无码系列| 国产午夜无码福利在线看网站| 欧美一区二区三区成人片在线| 亚无码乱人伦一区二区| 欧美成人一卡二卡三卡四卡| 日韩成人大屁股内射喷水| 国产精品美女一区二区视频 | 乱人伦人妻中文字幕| 小说区亚洲综合第1页| 综合色就爱涩涩涩综合婷婷| 精品国产av 无码一区二区三区 | 国产三级视频在线播放线观看| 亚洲人成网网址在线看| 国产亚洲成av片在线观看| 国产成人精品无码一区二区三区| 无码国模国产在线观看| 中文字幕日本人妻久久久免费| 亚洲国产成人精品无码区在线软件|