在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human CTD small phosphatase-like protein (CTDSPL)

Recombinant Human CTD small phosphatase-like protein (CTDSPL)

  • 中文名稱：
    Recombinant Human CTD small phosphatase-like protein(CTDSPL)
  • 貨號(hào)：
    CSB-YP006144HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human CTD small phosphatase-like protein(CTDSPL)
  • 貨號(hào)：
    CSB-EP006144HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human CTD small phosphatase-like protein(CTDSPL)
  • 貨號(hào)：
    CSB-EP006144HU-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human CTD small phosphatase-like protein(CTDSPL)
  • 貨號(hào)：
    CSB-BP006144HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human CTD small phosphatase-like protein(CTDSPL)
  • 貨號(hào)：
    CSB-MP006144HU
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    CTDSPL
  • Uniprot No.：
  • 別名：
    C3orf8; Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3; CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like; CTD small phosphatase-like protein; CTDSL_HUMAN; CTDSP-like; Ctdspl; hYA22; N-like protein; NIF-like protein; NLI-interacting factor 1; Nuclear LIM interactor-interacting factor 1; Protein YA22; RB protein serine phosphatase from chromosome 3; RBSP3; SCP3; Small C-terminal domain phosphatase 3; Small CTD phosphatase 3
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full length protein
  • 表達(dá)區(qū)域：
    1-276
  • 氨基酸序列
    MDGPAIITQV TNPKEDEGRL PGAGEKASQC NVSLKKQRSR SILSSFFCCF RDYNVEAPPP SSPSVLPPLV EENGGLQKGD QRQVIPIPSP PAKYLLPEVT VLDYGKKCVV IDLDETLVHS SFKPISNADF IVPVEIDGTI HQVYVLKRPH VDEFLQRMGQ LFECVLFTAS LAKYADPVAD LLDRWGVFRA RLFRESCVFH RGNYVKDLSR LGRELSKVII VDNSPASYIF HPENAVPVQS WFDDMTDTEL LDLIPFFEGL SREDDVYSML HRLCNR
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation.
  • 基因功能參考文獻(xiàn)：
    1. our data also suggests the importance ofLIMD1 and CDC25A in conjunction with HPV for use as diagnostic and prognostic markers of HNSCC, whereas RBSP3 as a prognostic marker only. PMID: 29672635
    2. data suggest that overexpression of p-RB1 in basal-parabasal layers of normal cervical epithelium was due to methylation/low functional-linked non-synonimous SNPs of P16 and RBSP3. This pattern was maintained during cervical carcinogenesis by additional deletion/mutation PMID: 27458253
    3. CTDSPL and Rb directly interact and can be involved in the common mechanism of cell cycle regulation. PMID: 27414789
    4. identified RBSP3, a phosphatase-like tumor suppressor, as a bona fide target of miR-100 and validated that RBSP3 was involved in cell differentiation and survival in acute myeloid leukemia PMID: 21643017
    5. tumor suppressor genes RBSP3/CTDSPL, NPRL2/G21 and RASSF1A are downregulated in primary non-small cell lung cancer PMID: 20193080
    6. dysregulation of hMLH1, ITGA9, and RBSP3 associated multiple cellular pathways are needed for the development of early dysplastic lesions of the head and neck. PMID: 20412120
    7. In cervical intraepithelial neoplasms and uterine cervical carinoma, RBSP3 is oftne deletd, compared with other genes. PMID: 19885927
    8. analysis of RBSP3/HYA22located in the AP20 region, and evidence for tumor suppressor function PMID: 15051889
    9. SCP3 acts as a phosphatase for regulatory phosphorylations in the linker regions of Smad1 and Smad2. PMID: 17085434
    10. Frequent alterations of RBSP3 at chromosomal 3p22.3 region in early and late-onset breast carcinoma are reported with reference to clinical and prognostic significance. PMID: 19016758
    11. Down-regulation of RBSP3/CTDSPL, NPRL2/G21, RASSF1A, ITGA9, HYAL1 and HYAL2 genes in non-small cell lung cancer PMID: 19140316
    12. This is the first report of high frequencies of somatic mutations in RASSF1 and RBSP3 in different cancers suggesting it may underlay the mutator phenotype of cancer. PMID: 19478941

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus.
  • 組織特異性：
    Expression is restricted to non-neuronal tissues.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 16890

    OMIM: 608592

    KEGG: hsa:10217

    STRING: 9606.ENSP00000273179

    UniGene: Hs.475963



主站蜘蛛池模板： 国产熟妇高潮呻吟喷水| 中文字幕av中文字无码亚| 国产高清av在线播放| 青草影院内射中出高潮| 六月丁香亚洲综合在线视频 | 精品四虎国产在免费观看| 国产精品青草久久久久福利99 | 国自产拍偷拍精品啪啪模特| 欧美日韩不卡视频合集| 国产日产欧产精品精品ai| 免费人成网站视频在线观看| 香蕉久久人人97超碰caoproen| 狠狠躁18三区二区一区| 国产乱人偷精品人妻a片| 国模无码一区二区三区| 成人伊人亚洲人综合网站| 天堂а√中文在线| 日韩乱码人妻无码中文视频| 国产三级在线观看完整版| 亚洲国产无线乱码在线观看| 狼人大香伊蕉国产www亚洲| 国产办公室无码视频在线观看| 国产+成+人+亚洲欧洲自线| 人妻av无码中文专区久久| 欧美日韩在线视频一区| 日本精品少妇一区二区三区| 欧美人与禽猛交狂配| 一本久道久久综合久久爱| 国产成人久久久精品二区三区 | 体验区试看120秒啪啪免费 | 日本亚洲欧洲无免费码在线| 国产97在线 | 中文| 真人做人试看60分钟免费视频| 新版天堂8中文在线最新版官网| 中国少妇内射xxxhd免费| 一本之道高清无码视频| 四川少妇被弄到高潮| 在线观看的av免费网站| 国模gogo无码人体啪啪| 免费中文字幕日韩欧美| 好了av四色综合无码久久|