在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human C-X-C motif chemokine 17 (CXCL17)

Recombinant Human C-X-C motif chemokine 17 (CXCL17)

  • 中文名稱：
    Recombinant Human C-X-C motif chemokine 17(CXCL17)
  • 貨號：
    CSB-YP761497HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human C-X-C motif chemokine 17(CXCL17)
  • 貨號：
    CSB-EP761497HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human C-X-C motif chemokine 17(CXCL17)
  • 貨號：
    CSB-EP761497HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human C-X-C motif chemokine 17(CXCL17)
  • 貨號：
    CSB-BP761497HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human C-X-C motif chemokine 17(CXCL17)
  • 貨號：
    CSB-MP761497HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    CXCL17
  • Uniprot No.：
  • 別名：
    CXCL17; VCC1; UNQ473/PRO842C-X-C motif chemokine 17; 6-Cys CXCL17; Dendritic cell and monocyte chemokine-like protein; DMC; VEGF coregulated chemokine 1) [Cleaved into: 4-Cys CXCL17]
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區(qū)域：
    22-119
  • 氨基酸序列
    SSLNPGVAR GHRDRGQASR RWLQEGGQEC ECKDWFLRAP RRKFMTVSGL PKKQCPCDHF KGNVKKTRHQ RHHRKPNKHS RACQQFLKQC QLRSFALPL
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Chemokine that acts as chemoattractant for monocytes, macrophages and dendritic cells. Plays a role in angiogenesis and possibly in the development of tumors. Acts as an anti-inflammatory in the stomach. May play a role in the innate defense against infections. Activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions.; seems exhibit much higher chemoattractant potency on monocytes and macrophages than 6-Cys CXCL17.
  • 基因功能參考文獻：
    1. High Lymph node CXCL17 messenger RNA is associated with colon cancer. PMID: 30198422
    2. High expression of CXCL17 correlates with shorter overall survival of breast cancer patients.CXCL17 interacts with CXCR8 in breast cancer cells. PMID: 28943434
    3. CXCL17 attenuates Imiquimod -induced psoriasis-like skin inflammation by recruiting myeloid-derived suppressor cells and regulatory T cells , which may be important for regulating excessive inflammation in psoriasis skin. PMID: 28389593
    4. This article shows that GPR35 is the receptor of CXCL17. PMID: 25411203
    5. CXCL17 production correlated with adverse immune infiltration and might be an important target for anti-HCC therapies. PMID: 25303284
    6. We conclude that CXCL17 is an antimicrobial mucosal chemokine that may play a role in the pathogenesis of interstitial lung diseases PMID: 22611239
    7. these results suggest that VCC-1 is involved in cisplatin-induced apoptosis of HepG2 cells, and also provides some evidence for VCC-1 as a potential cellular target for chemotherapy. PMID: 22425983
    8. An Fc-fusion protein of 35kDa with a modified human immunoglobulin IgG1 Fc domain is capable of inhibiting CC chemokine-induced calcium flux, chemotaxis, and beta-arrestin recruitment in primary macrophages and transfected cells. PMID: 21586597
    9. Immune surveillance occurs during the early intraepithelial stages of human pancreatic carcinogenesis and is mediated by expression of CXCL17 and ICAM2. PMID: 20955708
    10. DMC induces migration of monocytes and immature dendritic cells. Expression studies show that DMC is constitutively expressed in lung, suggesting a potential role for DMC in recruiting monocytes and dendritic cells from blood into lung parenchyma PMID: 16455961
    11. VCC1 plays a role in angiogenesis and possibly in the development of tumors in some tissue types PMID: 16989774
    12. These results strongly suggest that VCC-1 plays an important role in hepatocellular carcinoma cell invasion and tumor growth. PMID: 19657564

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Intercrine alpha (chemokine CxC) family
  • 組織特異性：
    Detected in trachea, stomach, lung and skeletal muscle. Detected in intestine and in normal and asthmatic lung (at protein level). Breast tumors showed 3- to 24-fold up-regulation.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 19232

    OMIM: 611387

    KEGG: hsa:284340

    STRING: 9606.ENSP00000472467

    UniGene: Hs.445586



主站蜘蛛池模板： 人妻精品无码一区二区三区| 中文字幕乱码在线人视频| 女人下面毛多水多视频| 国产真人做爰视频免费| 中文字幕丰满乱子无码视频| 久久99精品久久久久久齐齐| 熟妇人妻中文字幕无码老熟妇| 国产最新精品自产在线观看| 国产精品亚洲综合一区在线观看| 国产精品久久久久久无毒不卡| 国产精品久久久一区二区三区| 国产美女a做受大片观看| 蜜臀av一区二区| 在线a亚洲视频播放在线观看| 亚洲精品久久久久avwww潮水| 国产乱子伦一区二区三区视频播放| 麻豆国产尤物av尤物在线观看| 大肉大捧一进一出好爽| 成人网站www污污污网站| 日本韩国的免费观看视频| 国内揄拍国内精品人妻| 男阳茎进女阳道视频大全| 激情内射亚洲一区二区三区| 国产老熟女狂叫对白| 欧美成妇人吹潮在线播放| 一区二区亚洲精品国产精华液| 精品无码av无码免费专区| 久久久久人妻一区精品果冻| 国产成年码av片在线观看| 国产成人啪精品视频免费网站软件| 国产97在线 | 亚洲| 亚洲精华国产精华精华液网站| 免费人成在线观看| 亚洲成av人片天堂网| 国产精品无码一区二区在线看| 天天狠天天透天干天天| 亚洲不乱码卡一卡二卡4卡5| 毛茸茸性xxxx毛茸茸毛茸茸| 丰满熟女人妻中文字幕免费 | 嫩b人妻精品一区二区三区| 欧美日韩在线视频|