在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human C-Maf-inducing protein (CMIP)

Recombinant Human C-Maf-inducing protein (CMIP)

  • 中文名稱：
    Recombinant Human C-Maf-inducing protein(CMIP)
  • 貨號：
    CSB-YP815577HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human C-Maf-inducing protein(CMIP)
  • 貨號：
    CSB-EP815577HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human C-Maf-inducing protein(CMIP)
  • 貨號：
    CSB-EP815577HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human C-Maf-inducing protein(CMIP)
  • 貨號：
    CSB-BP815577HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human C-Maf-inducing protein(CMIP)
  • 貨號：
    CSB-MP815577HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    CMIP
  • Uniprot No.：
  • 別名：
    C-Maf-inducing protein; c-Mip; cmip; CMIP_HUMAN; KIAA1694; Tc-Mip; TCMIP; Truncated c-Maf-inducing protein
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-773
  • 氨基酸序列
    MDVTSSSGGG GDPRQIEETK PLLGGDVSAP EGTKMGAVPC RRALLLCNGM RYKLLQEGDI QVCVIRHPRT FLSKILTSKF LRRWEPHHLT LADNSLASAT PTGYMENSVS YSAIEDVQLL SWENAPKYCL QLTIPGGTVL LQAANSYLRD QWFHSLQWKK KIYKYKKVLS NPSRWEVVLK EIRTLVDMAL TSPLQDDSIN QAPLEIVSKL LSENTNLTTQ EHENIIVAIA PLLENNHPPP DLCEFFCKHC RERPRSMVVI EVFTPVVQRI LKHNMDFGKC PRLRLFTQEY ILALNELNAG MEVVKKFIQS MHGPTGHCPH PRVLPNLVAV CLAAIYSCYE EFINSRDNSP SLKEIRNGCQ QPCDRKPTLP LRLLHPSPDL VSQEATLSEA RLKSVVVASS EIHVEVERTS TAKPALTASA GNDSEPNLID CLMVSPACST MSIELGPQAD RTLGCYVEIL KLLSDYDDWR PSLASLLQPI PFPKEALAHE KFTKELKYVI QRFAEDPRQE VHSCLLSVRA GKDGWFQLYS PGGVACDDDG ELFASMVHIL MGSCYKTKKF LLSLAENKLG PCMLLALRGN QTMVEILCLM LEYNIIDNND TQLQIISTLE STDVGKRMYE QLCDRQRELK ELQRKGGPTR LTLPSKSTDA DLARLLSSGS FGNLENLSLA FTNVTSACAE HLIKLPSLKQ LNLWSTQFGD AGLRLLSEHL TMLQVLNLCE TPVTDAGLLA LSSMKSLCSL NMNSTKLSAD TYEDLKAKLP NLKEVDVRYT EAW
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Plays a role in T-cell signaling pathway. Isoform 2 may play a role in T-helper 2 (Th2) signaling pathway and seems to represent the first proximal signaling protein that links T-cell receptor-mediated signal to the activation of c-Maf Th2 specific factor.
  • 基因功能參考文獻：
    1. Genome-wide significant (P < 5 x 10(-8) ) interaction with MTNR1B and joint effects were detected for CMIP intronic rs17197883. PMID: 29691896
    2. each copy of CMIP rs2925979_T allele was associated with a 29% higher risk of T2DM in females (p = 9.30 x 10(-4)), while it was not significantly associated with T2DM in males (p = 0.705). PMID: 29597287
    3. CMIP knockdown was observed to result in the downregulation of MDM2 and mitogen activated protein kinase (MAPK) expression at the mRNA level and CMIP was a direct target of miR1013p. PMID: 28944848
    4. CMIP is oncogenic and could be a potential target for human glioma diagnosis and therapy. PMID: 28744466
    5. These findings suggest that CMIP haploinsufficiency is the likely cause of syndromic Autism spectrum disorder in our patients. PMID: 28504353
    6. Wilm's tumor protein (WT1) bound to 2 WT1 response elements, located at positions -290/-274 and -57/-41 relative to transcription start site. PMID: 27650733
    7. Results suggest that c-mip and RelA define two distinct types of renal damage associated with VEGF-targeted therapies. PMID: 24067439
    8. c-mip has an active role in the podocyte disorders of membranous nephropathy. PMID: 23302718
    9. These results suggest that alterations in NF-kappaB activity might result from the up-regulation of c-mip and are likely to contribute to podocyte disorders in cases of idiopathic nephrotic syndrome. PMID: 22507836
    10. we provide novel evidence that the language-disorder candidate gene CMIP is implicated in reading processes. PMID: 21457949
    11. Eight suggestive significant loci were detected with a series of genes expressed within the inner ear that underlie the auditory function, such as: DCLK1, PTPRD, GRM8, CMIP. PMID: 21493956
    12. results identify c-mip as a key component in the molecular pathogenesis of acquired podocyte diseases PMID: 20484117
    13. Induction of c-mip in Hodgkin-Reed Sternberg cells and podocytes is associated with minimal change nephrotic syndrome in classical Hodgkin lymphoma. PMID: 20200355
    14. results suggest that Tc-mip plays a critical role in Th2 signaling pathway and represents the first proximal signaling protein which links TCR-mediated signal to the activation of c-maf Th2 specific factor PMID: 12939343
    15. Filamin-A interacts with c-mip/Tc-mip in a new T-cell signaling pathway. PMID: 15128042
    16. c-mip inhibits the degradation of I-kappaBalpha and impedes the dissociation of the NF-kappaB/I-kappaBalpha complexes. PMID: 19019440
    17. CMIP modulates phonological short-term memory in language impairment. PMID: 19646677

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Cytoplasm.
  • 組織特異性：
    Isoform 1 is expressed in peripheral blood mononuclear cells and kidney. Lower expression in brain and liver. Expression is down-regulated in activated cells. Isoform 2 is expressed in lymphocyte precursors, however, expression shuts down during maturatio
  • 數據庫鏈接：

    HGNC: 24319

    OMIM: 610112

    KEGG: hsa:80790

    STRING: 9606.ENSP00000446100

    UniGene: Hs.594095



主站蜘蛛池模板： 久久久精品人妻一区亚美研究所| 五十路熟女丰满大屁股| 丁香激情综合久久伊人久久| 亚洲一线二线三线写真| 日韩欧国产精品一区综合无码| 日本成a人片在线播放| 无码人妻丰满熟妇啪啪欧美| 大香伊蕉国产av| av无码人妻无码男人的天堂| 日本真人边吃奶边做爽电影| 麻花传媒在线观看免费| 国产激情综合五月久久| 亚洲欧美成人综合图区| 涩欲国产一区二区三区四区| 老鲁夜夜老鲁| 国产精品欧美福利久久| 亚洲а∨天堂久久精品| 97人妻熟女成人免费视频色戒| 色综合久久无码中文字幕 | 成人做受120秒试看试看视频| 国产奶头好大揉着好爽视频| 老司机午夜免费精品视频| 日韩av毛片无码免费| 日韩人妻无码中文字幕视频| 天天摸天天碰天天添| 亚洲国产精品久久久久婷婷软件| 少妇爱做高清免费视频| 久久综合九色综合97欧美| 欧美亚洲一区二区三区| 9999国产精品欧美久久久久久| 好了av第四综合无码久久| 亚洲欧美精品aaaaaa片| av无码国产精品麻豆| 在线永久无码不卡av| 人妻去按摩店被黑人按中出| 中文字幕精品久久久久人妻红杏ⅰ| 伊人久久大香线蕉精品| 国产sm重味一区二区三区| 黄页网站视频| 日韩免费无码视频一区二区三区 | 久久久久久一区国产精品|