在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human C-Maf-inducing protein (CMIP)

Recombinant Human C-Maf-inducing protein (CMIP)

  • 中文名稱：
    Recombinant Human C-Maf-inducing protein(CMIP)
  • 貨號：
    CSB-YP815577HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human C-Maf-inducing protein(CMIP)
  • 貨號：
    CSB-EP815577HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human C-Maf-inducing protein(CMIP)
  • 貨號：
    CSB-EP815577HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human C-Maf-inducing protein(CMIP)
  • 貨號：
    CSB-BP815577HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human C-Maf-inducing protein(CMIP)
  • 貨號：
    CSB-MP815577HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    CMIP
  • Uniprot No.：
  • 別名：
    C-Maf-inducing protein; c-Mip; cmip; CMIP_HUMAN; KIAA1694; Tc-Mip; TCMIP; Truncated c-Maf-inducing protein
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-773
  • 氨基酸序列
    MDVTSSSGGG GDPRQIEETK PLLGGDVSAP EGTKMGAVPC RRALLLCNGM RYKLLQEGDI QVCVIRHPRT FLSKILTSKF LRRWEPHHLT LADNSLASAT PTGYMENSVS YSAIEDVQLL SWENAPKYCL QLTIPGGTVL LQAANSYLRD QWFHSLQWKK KIYKYKKVLS NPSRWEVVLK EIRTLVDMAL TSPLQDDSIN QAPLEIVSKL LSENTNLTTQ EHENIIVAIA PLLENNHPPP DLCEFFCKHC RERPRSMVVI EVFTPVVQRI LKHNMDFGKC PRLRLFTQEY ILALNELNAG MEVVKKFIQS MHGPTGHCPH PRVLPNLVAV CLAAIYSCYE EFINSRDNSP SLKEIRNGCQ QPCDRKPTLP LRLLHPSPDL VSQEATLSEA RLKSVVVASS EIHVEVERTS TAKPALTASA GNDSEPNLID CLMVSPACST MSIELGPQAD RTLGCYVEIL KLLSDYDDWR PSLASLLQPI PFPKEALAHE KFTKELKYVI QRFAEDPRQE VHSCLLSVRA GKDGWFQLYS PGGVACDDDG ELFASMVHIL MGSCYKTKKF LLSLAENKLG PCMLLALRGN QTMVEILCLM LEYNIIDNND TQLQIISTLE STDVGKRMYE QLCDRQRELK ELQRKGGPTR LTLPSKSTDA DLARLLSSGS FGNLENLSLA FTNVTSACAE HLIKLPSLKQ LNLWSTQFGD AGLRLLSEHL TMLQVLNLCE TPVTDAGLLA LSSMKSLCSL NMNSTKLSAD TYEDLKAKLP NLKEVDVRYT EAW
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Plays a role in T-cell signaling pathway. Isoform 2 may play a role in T-helper 2 (Th2) signaling pathway and seems to represent the first proximal signaling protein that links T-cell receptor-mediated signal to the activation of c-Maf Th2 specific factor.
  • 基因功能參考文獻：
    1. Genome-wide significant (P < 5 x 10(-8) ) interaction with MTNR1B and joint effects were detected for CMIP intronic rs17197883. PMID: 29691896
    2. each copy of CMIP rs2925979_T allele was associated with a 29% higher risk of T2DM in females (p = 9.30 x 10(-4)), while it was not significantly associated with T2DM in males (p = 0.705). PMID: 29597287
    3. CMIP knockdown was observed to result in the downregulation of MDM2 and mitogen activated protein kinase (MAPK) expression at the mRNA level and CMIP was a direct target of miR1013p. PMID: 28944848
    4. CMIP is oncogenic and could be a potential target for human glioma diagnosis and therapy. PMID: 28744466
    5. These findings suggest that CMIP haploinsufficiency is the likely cause of syndromic Autism spectrum disorder in our patients. PMID: 28504353
    6. Wilm's tumor protein (WT1) bound to 2 WT1 response elements, located at positions -290/-274 and -57/-41 relative to transcription start site. PMID: 27650733
    7. Results suggest that c-mip and RelA define two distinct types of renal damage associated with VEGF-targeted therapies. PMID: 24067439
    8. c-mip has an active role in the podocyte disorders of membranous nephropathy. PMID: 23302718
    9. These results suggest that alterations in NF-kappaB activity might result from the up-regulation of c-mip and are likely to contribute to podocyte disorders in cases of idiopathic nephrotic syndrome. PMID: 22507836
    10. we provide novel evidence that the language-disorder candidate gene CMIP is implicated in reading processes. PMID: 21457949
    11. Eight suggestive significant loci were detected with a series of genes expressed within the inner ear that underlie the auditory function, such as: DCLK1, PTPRD, GRM8, CMIP. PMID: 21493956
    12. results identify c-mip as a key component in the molecular pathogenesis of acquired podocyte diseases PMID: 20484117
    13. Induction of c-mip in Hodgkin-Reed Sternberg cells and podocytes is associated with minimal change nephrotic syndrome in classical Hodgkin lymphoma. PMID: 20200355
    14. results suggest that Tc-mip plays a critical role in Th2 signaling pathway and represents the first proximal signaling protein which links TCR-mediated signal to the activation of c-maf Th2 specific factor PMID: 12939343
    15. Filamin-A interacts with c-mip/Tc-mip in a new T-cell signaling pathway. PMID: 15128042
    16. c-mip inhibits the degradation of I-kappaBalpha and impedes the dissociation of the NF-kappaB/I-kappaBalpha complexes. PMID: 19019440
    17. CMIP modulates phonological short-term memory in language impairment. PMID: 19646677

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Cytoplasm.
  • 組織特異性：
    Isoform 1 is expressed in peripheral blood mononuclear cells and kidney. Lower expression in brain and liver. Expression is down-regulated in activated cells. Isoform 2 is expressed in lymphocyte precursors, however, expression shuts down during maturatio
  • 數據庫鏈接：

    HGNC: 24319

    OMIM: 610112

    KEGG: hsa:80790

    STRING: 9606.ENSP00000446100

    UniGene: Hs.594095



主站蜘蛛池模板： 亚洲国产成人一区二区三区| 蜜臀av无码精品人妻色欲| 色妞色综合久久夜夜| 无罩大乳的熟妇正在播放| 在线观看的网站| 女人喷水高潮时的视频网站| 永久免费精品精品永久-夜色 | 久久久久久99av无码免费网站 | 狠狠97人人婷婷五月| 曰本女人与公拘交酡| 熟女人妻aⅴ一区二区三区麻豆| 久久久久久国产精品mv| 在线成 人av影院| 国产乱人伦无无码视频试看| 综合人妻久久一区二区精品 | 熟女人妻高清一区二区三区 | 亚洲国产成人av在线观看| 天天综合色天天综合色h| 亚洲成a人片在线观看天堂无码不卡| 中国精学生妹品射精久久| 国产精品第12页| 日韩一本之道一区中文字幕| 亚洲va在线va天堂xxxx中文| 亚洲国产精品久久精品成人网站| 色综合视频一区二区三区44| 无遮挡裸体免费视频尤物| 久久久成人精品av四区| 新普新京亚洲欧美日韩国产 | 激情综合丁香五月| 正在播放老肥熟妇露脸| 国产喷水福利在线视频| 久久亚洲精品无码gv| 亚洲午夜未满十八勿入| 国产精品av在线| 精品人妻少妇一区二区三区在线| 永久免费男同av无码入口| 太粗太深了太紧太爽了动态图男男| 精品久久久久久无码人妻热| 香蕉伊蕉伊中文视频在线| 国产麻豆精品福利在线| 午夜无码国产理论在线|