在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Bone morphogenetic protein 10 (BMP10)

Recombinant Human Bone morphogenetic protein 10 (BMP10)

  • 中文名稱：
    Recombinant Human Bone morphogenetic protein 10(BMP10)
  • 貨號：
    CSB-YP002734HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Bone morphogenetic protein 10(BMP10)
  • 貨號：
    CSB-EP002734HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Bone morphogenetic protein 10(BMP10)
  • 貨號：
    CSB-EP002734HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Bone morphogenetic protein 10(BMP10)
  • 貨號：
    CSB-BP002734HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Bone morphogenetic protein 10(BMP10)
  • 貨號：
    CSB-MP002734HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    BMP10
  • Uniprot No.：
  • 別名：
    BMP-10; Bmp10; BMP10_HUMAN; Bone morphogenetic protein 10; Bone morphogenetic protein 10 preproprotein; MGC126783; OTTHUMP00000159973
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    317-424
  • 氨基酸序列
    NAKG NYCKRTPLYI DFKEIGWDSW IIAPPGYEAY ECRGVCNYPL AEHLTPTKHA IIQALVHLKN SQKASKACCV PTKLEPISIL YLDKGVVTYK FKYEGMAVSE CGCR
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
  • 基因功能參考文獻：
    1. Data suggest BMP9/GDF2 and BMP10 synergize with TNFA to increase monocyte recruitment to vascular endothelial cells; process appears to be mediated mainly via ALK2/ACVR1 (which exhibits protein kinase activity). These studies used in vitro flow monocyte adhesion assay. (BMP9 = growth differentiation factor 2; BMP10 = bone morphogenetic protein 10; TNFA = tumor necrosis factor alpha; ALK2/ACVR1 = activin A receptor type 1) PMID: 28646109
    2. Bone morphogenetic protein (BMP)9 and BMP10 are high affinity ligands for activin receptor-like kinase 1 (ALK1). PMID: 27528761
    3. Forced expression of BMP10 in gastric cancer (GC) cells inhibited its growth and migration, while knocking down the expression of BMP10 in GC cells promoted cell growth, migration, and metastasis. PMID: 26419594
    4. The Prodomain-bound Form of Bone Morphogenetic Protein 10 Is Biologically Active on Endothelial Cells. PMID: 26631724
    5. BMP10, is elevated in the stenotic colon segment of Hirschsprung disease patients, and BMP10 signaling may play a pivotal role in disease development. PMID: 24551273
    6. Low expression of bone morphogenetic protein-10 is associated with urothelial cancer of the bladder. PMID: 23645739
    7. Soluble endoglin specifically binds bone morphogenetic proteins 9 and 10 via its orphan domain, inhibits blood vessel formation, and suppresses tumor growth. PMID: 21737454
    8. Furin is the major processing enzyme of the cardiac-specific growth factor bone morphogenetic protein 10. PMID: 21550985
    9. Bone morphogenetic protein-10 (BMP-10) may function as a tumor suppressor in breast cancer. PMID: 20608934
    10. Hypertension induced expression of prohypertrophic BMP10, and the hypertrophic effect of BMP10 was modulated, at least in part, by its binding to Tcap at the Z disc. PMID: 17921333
    11. Describes the cloning and expression of murine BMP-10. PMID: 10072785

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    TGF-beta family
  • 組織特異性：
    Detected in mammary epithelia (at protein level).
  • 數據庫鏈接：

    HGNC: 20869

    OMIM: 608748

    KEGG: hsa:27302

    STRING: 9606.ENSP00000295379

    UniGene: Hs.158317



主站蜘蛛池模板： 精品欧美乱码久久久久久1区2区| 噜噜色综合噜噜色噜噜色| 人妻丝袜中文无码av影音先锋专区 | 国产男女爽爽爽免费视频| 人妻互换 综合| 色综合久久久久综合99| 久久综合九色综合欧美就去吻| 国产日韩亚洲大尺度高清| 国产在线精品一品二区| 中字乱码视频| 成人永久免费网站在线观看| 亚洲午夜无码毛片av久久京东热| 亚洲中文字幕丝祙制服| 日本少妇内射视频播放舔| 欧美成人午夜免费影院手机在线看| 免费特级黄毛片| 18禁裸男晨勃露j毛免费观看 | 国产真实乱对白精彩久久 | 亚洲综合无码精品一区二区三区| 久久影视久久午夜| 在线无码免费的毛片视频| 一本色道久久88精品综合| 无码专区久久综合久中文字幕| 四虎精品成人免费视频| 火箭视频在线观看精品| 在线无码av一区二区三区| 欧美情侣性视频| 波多野结av衣东京热无码专区| 亚洲精品国产熟女久久久| 国产巨大爆乳在线观看| 国产午夜无码福利在线看网站| 国产精品久久久久久福利| 日韩成av人片在线观看| 国产精品无码av片在线观看播| 亚洲中文字幕a∨在线| 国产精品久久| 天堂а√中文在线官网| 久久精品农村毛片| 天码欧美日本一道免费| 国产熟女高潮视频| 影音先锋人妻啪啪av资源网站 |