在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Bile acid-CoA:amino acid N-acyltransferase (BAAT)

Recombinant Human Bile acid-CoA:amino acid N-acyltransferase (BAAT)

  • 中文名稱：
    Recombinant Human Bile acid-CoA:amino acid N-acyltransferase(BAAT)
  • 貨號：
    CSB-YP613484HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Bile acid-CoA:amino acid N-acyltransferase(BAAT)
  • 貨號：
    CSB-EP613484HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Bile acid-CoA:amino acid N-acyltransferase(BAAT)
  • 貨號：
    CSB-EP613484HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Bile acid-CoA:amino acid N-acyltransferase(BAAT)
  • 貨號：
    CSB-BP613484HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Bile acid-CoA:amino acid N-acyltransferase(BAAT)
  • 貨號：
    CSB-MP613484HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    BAAT
  • Uniprot No.：
  • 別名：
    FLJ20300; BAAT; BAAT_HUMAN; BACAT; BAT; Bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase); Bile acid CoA:amino acid N acyltransferase; Bile acid Coenzyme A amino acid N acyltransferase glycine N choloyltransferase; Bile acid Coenzyme A: amino acid N acyltransferase; Bile acid-CoA:amino acid N-acyltransferase; Glycine N choloyltransferase; Glycine N-choloyltransferase; Long chain fatty acyl CoA hydrolase; Long-chain fatty-acyl-CoA hydrolase; MGC104432
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-418
  • 氨基酸序列
    MIQLTATPVS ALVDEPVHIR ATGLIPFQMV SFQASLEDEN GDMFYSQAHY RANEFGEVDL NHASSLGGDY MGVHPMGLFW SLKPEKLLTR LLKRDVMNRP FQVQVKLYDL ELIVNNKVAS APKASLTLER WYVAPGVTRI KVREGRLRGA LFLPPGEGLF PGVIDLFGGL GGLLEFRASL LASRGFASLA LAYHNYEDLP RKPEVTDLEY FEEAANFLLR HPKVFGSGVG VVSVCQGVQI GLSMAIYLKQ VTATVLINGT NFPFGIPQVY HGQIHQPLPH SAQLISTNAL GLLELYRTFE TTQVGASQYL FPIEEAQGQF LFIVGEGDKT INSKAHAEQA IGQLKRHGKN NWTLLSYPGA GHLIEPPYSP LCCASTTHDL RLHWGGEVIP HAAAQEHAWK EIQRFLRKHL IPDVTSQL
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Catalyzes the amidation of bile acids (BAs) with the amino acids taurine and glycine. More than 95% of the BAs are N-acyl amidates with glycine and taurine. Amidation of BAs in the liver with glycine or taurine prior to their excretion into bile is an important biochemical event in bile acid metabolism. This conjugation (or amidation) plays several important biological roles in that it promotes the secretion of BAs and cholesterol into bile and increases the detergent properties of BAs in the intestine, which facilitates lipid and vitamin absorption. May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs.
  • 基因功能參考文獻：
    1. BAAT polymorphisms might not be associated with anti-tuberculosis drug-induced hepatotoxicity in the Chinese population PMID: 27155186
    2. These results indicate that even small changes in the carboxy terminus of BAAT can have significant effects on activity and substrate specificity PMID: 27230263
    3. Case Report: mmunostaining may facilitate diagnosis in bile-acid amidation defects in bile acid-CoA: amino acid N-acyltransferase deficiency. PMID: 22783059
    4. there is an essential catalytic triad within hBAT consisting of Cys-235, His-362, and Asp-328 with Cys-235 serving as the probable nucleophile and thus the site of covalent attachment of the bile acid molecule PMID: 12239217
    5. Familial hypercholanemia in Amish individuals is associated with mutations in tight junction protein 2 (encoded by TJP2, also known as ZO-2) and bile acid Coenzyme A: amino acid N-acyltransferase (encoded by BAAT). PMID: 12704386
    6. cytosolic BACAT enzyme may play important roles in protection against toxicity by accumulation of unconjugated bile acids and non-esterified very long-chain fatty acids PMID: 12810727
    7. hBAAT and rBaat are peroxisomal enzymes present in undetectable amounts in the cytosol. Unconjugated or deconjugated bile salts returning to the liver need to shuttle through the peroxisome before reentering the enterohepatic circulation. PMID: 17256745
    8. identification of 3 novel SNPs, 147C>T in exon 2 (silent), 602G>C in exon 3 (Arg201Pro) & 1134C>T in exon 4 (silent), in the BAAT gene by resequencing the entire coding region and the exon-intron junctions of 100 Japanese individuals PMID: 17495420
    9. Data show that dose-response inactivation by 4HNE (4-hydroxynonenal) of hBAT (human bile acid CoA:amino acid N-acyltransferase) and CKBB (cytosolic brain isoform of creatine kinase) is associated with site-specific modifications. PMID: 18793185

    顯示更多

    收起更多

  • 相關疾病：
    Familial hypercholanemia (FHCA)
  • 亞細胞定位：
    Cytoplasm, cytosol. Peroxisome.
  • 蛋白家族：
    C/M/P thioester hydrolase family
  • 組織特異性：
    Expressed in liver, gallbladder mucosa and pancreas.
  • 數據庫鏈接：

    HGNC: 932

    OMIM: 602938

    KEGG: hsa:570

    STRING: 9606.ENSP00000259407

    UniGene: Hs.284712



主站蜘蛛池模板： 少妇被爽到高潮在线观看| 久久精品欧美日韩精品| 偷偷要色偷偷中文无码| 亚洲日韩a∨无码久| 免免费国产aaaaa片| 熟妇与小伙子matur老熟妇e | 欧美牲交a欧美牲交| 成人精品一区二区三区中文字幕| 国产精品白丝久久av网站| 无码专区丰满人妻斩六十路| 久久天天躁狠狠躁夜夜2020一| 国产午夜伦鲁鲁| 青青草国产线观看| 亚洲区激情区无码区日韩区| 欧美牲交40_50a欧美牲交aⅴ| 伊人蕉久中文字幕无码专区| 乱中年女人伦av二区| 人妻精品人妻无码一区二区三区 | 久久久久久无码日韩欧美| 亚洲日韩欧美在线成人| 国产自产v一区二区三区c| 亚洲人av在线无码影院观看| 亚洲成av人片天堂网九九| 亚洲精品一区二三区不卡| 久久久久久人妻一区二区三区| 色www永久免费视频首页| 亚洲精品成人福利网站app| 欧美激情a∨在线视频播放| 久久精品中文无码资源站| 国产ktv交换配乱婬视频| 波多野结衣初尝黑人| 久久国产色av免费看| 婷婷色爱区综合五月激情| 精品国产自在精品国产精华天| 熟妇与小伙子matur老熟妇e | 亚洲高清国产拍精品闺蜜合租| 午夜熟女插插xx免费视频| 永久黄网站免费视频性色| 99热这里只有是精品2| 老熟女乱子伦| 日产无码中文字幕av|