在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. BAAT Antibody

BAAT Antibody

  • 中文名稱：
    BAAT兔多克隆抗體
  • 貨號：
    CSB-PA002523GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    BAAT
  • 別名：
    FLJ20300 antibody; BAAT antibody; BAAT_HUMAN antibody; BACAT antibody; BAT antibody; Bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase) antibody; Bile acid CoA:amino acid N acyltransferase antibody; Bile acid Coenzyme A amino acid N acyltransferase glycine N choloyltransferase antibody; Bile acid Coenzyme A: amino acid N acyltransferase antibody; Bile acid-CoA:amino acid N-acyltransferase antibody; Glycine N choloyltransferase antibody; Glycine N-choloyltransferase antibody; Long chain fatty acyl CoA hydrolase antibody; Long-chain fatty-acyl-CoA hydrolase antibody; MGC104432 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human BAAT
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Catalyzes the amidation of bile acids (BAs) with the amino acids taurine and glycine. More than 95% of the BAs are N-acyl amidates with glycine and taurine. Amidation of BAs in the liver with glycine or taurine prior to their excretion into bile is an important biochemical event in bile acid metabolism. This conjugation (or amidation) plays several important biological roles in that it promotes the secretion of BAs and cholesterol into bile and increases the detergent properties of BAs in the intestine, which facilitates lipid and vitamin absorption. May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs.
  • 基因功能參考文獻：
    1. BAAT polymorphisms might not be associated with anti-tuberculosis drug-induced hepatotoxicity in the Chinese population PMID: 27155186
    2. These results indicate that even small changes in the carboxy terminus of BAAT can have significant effects on activity and substrate specificity PMID: 27230263
    3. Case Report: mmunostaining may facilitate diagnosis in bile-acid amidation defects in bile acid-CoA: amino acid N-acyltransferase deficiency. PMID: 22783059
    4. there is an essential catalytic triad within hBAT consisting of Cys-235, His-362, and Asp-328 with Cys-235 serving as the probable nucleophile and thus the site of covalent attachment of the bile acid molecule PMID: 12239217
    5. Familial hypercholanemia in Amish individuals is associated with mutations in tight junction protein 2 (encoded by TJP2, also known as ZO-2) and bile acid Coenzyme A: amino acid N-acyltransferase (encoded by BAAT). PMID: 12704386
    6. cytosolic BACAT enzyme may play important roles in protection against toxicity by accumulation of unconjugated bile acids and non-esterified very long-chain fatty acids PMID: 12810727
    7. hBAAT and rBaat are peroxisomal enzymes present in undetectable amounts in the cytosol. Unconjugated or deconjugated bile salts returning to the liver need to shuttle through the peroxisome before reentering the enterohepatic circulation. PMID: 17256745
    8. identification of 3 novel SNPs, 147C>T in exon 2 (silent), 602G>C in exon 3 (Arg201Pro) & 1134C>T in exon 4 (silent), in the BAAT gene by resequencing the entire coding region and the exon-intron junctions of 100 Japanese individuals PMID: 17495420
    9. Data show that dose-response inactivation by 4HNE (4-hydroxynonenal) of hBAT (human bile acid CoA:amino acid N-acyltransferase) and CKBB (cytosolic brain isoform of creatine kinase) is associated with site-specific modifications. PMID: 18793185

    顯示更多

    收起更多

  • 相關疾病：
    Familial hypercholanemia (FHCA)
  • 亞細胞定位：
    Cytoplasm, cytosol. Peroxisome.
  • 蛋白家族：
    C/M/P thioester hydrolase family
  • 組織特異性：
    Expressed in liver, gallbladder mucosa and pancreas.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 932

    OMIM: 602938

    KEGG: hsa:570

    STRING: 9606.ENSP00000259407

    UniGene: Hs.284712



主站蜘蛛池模板： 婷婷亚洲综合五月天小说| 欧美性videos高清精品| 国产精品久久久亚洲| 国产艳妇av在线出轨| 偷偷做久久久久网站| 国产亚洲精品久久久久9999| 午夜福利不卡片在线机免费视频| 欧美在线精彩视频免费播放| 欧美日韩亚洲国内综合网| 欧美又大粗又爽又黄大片视频| 亚洲精品一区二区三区在线观看| 国内精品免费久久久久软件| 韩国三级l中文字幕无码| 亚洲国产欧美在线人成app| 99国产精品久久久久久久日本竹| 国产又色又爽无遮挡免费动态图| 真人做人试看60分钟免费视频| 成 人 免 费 黄 色| 欧美欧洲成本大片免费| 国产精品一区二区久久国产| 精品国精品国产自在久国产87| 久久综合九色综合97婷婷| 欧洲女人性开放免费网站| 亚洲精品久久久久午夜福利| 欧美成a人片在线观看久| 国产综合色在线视频区| 成人精品视频在线观看不卡| 久久99er精品国产首页| 欧美人与动另类xxxx| 中文字幕日韩精品一区二区三区| 亚洲色无码国产精品网站可下载 | 不卡高清av手机在线观看| 精品无码久久久久国产app| 少妇粉嫩小泬喷水视频www| 日韩一本之道一区中文字幕| 综合久久久久6亚洲综合| 欧美性受xxxxzooz乱毛| 精品无码国产av一区二区三区| 国产私拍大尺度在线视频| 动漫精品无码h在线观看| 亚洲国产成人无码电影|