在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. BAAT Antibody

BAAT Antibody

  • 中文名稱：
    BAAT兔多克隆抗體
  • 貨號：
    CSB-PA907155
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA907155(BAAT Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA907155(BAAT Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human normal liver tissue, Primary antibody: CSB-PA907155(BAAT Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    BAAT
  • 別名：
    FLJ20300 antibody; BAAT antibody; BAAT_HUMAN antibody; BACAT antibody; BAT antibody; Bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase) antibody; Bile acid CoA:amino acid N acyltransferase antibody; Bile acid Coenzyme A amino acid N acyltransferase glycine N choloyltransferase antibody; Bile acid Coenzyme A: amino acid N acyltransferase antibody; Bile acid-CoA:amino acid N-acyltransferase antibody; Glycine N choloyltransferase antibody; Glycine N-choloyltransferase antibody; Long chain fatty acyl CoA hydrolase antibody; Long-chain fatty-acyl-CoA hydrolase antibody; MGC104432 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Fusion protein of Human BAAT
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the amidation of bile acids (BAs) with the amino acids taurine and glycine. More than 95% of the BAs are N-acyl amidates with glycine and taurine. Amidation of BAs in the liver with glycine or taurine prior to their excretion into bile is an important biochemical event in bile acid metabolism. This conjugation (or amidation) plays several important biological roles in that it promotes the secretion of BAs and cholesterol into bile and increases the detergent properties of BAs in the intestine, which facilitates lipid and vitamin absorption. May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs.
  • 基因功能參考文獻：
    1. BAAT polymorphisms might not be associated with anti-tuberculosis drug-induced hepatotoxicity in the Chinese population PMID: 27155186
    2. These results indicate that even small changes in the carboxy terminus of BAAT can have significant effects on activity and substrate specificity PMID: 27230263
    3. Case Report: mmunostaining may facilitate diagnosis in bile-acid amidation defects in bile acid-CoA: amino acid N-acyltransferase deficiency. PMID: 22783059
    4. there is an essential catalytic triad within hBAT consisting of Cys-235, His-362, and Asp-328 with Cys-235 serving as the probable nucleophile and thus the site of covalent attachment of the bile acid molecule PMID: 12239217
    5. Familial hypercholanemia in Amish individuals is associated with mutations in tight junction protein 2 (encoded by TJP2, also known as ZO-2) and bile acid Coenzyme A: amino acid N-acyltransferase (encoded by BAAT). PMID: 12704386
    6. cytosolic BACAT enzyme may play important roles in protection against toxicity by accumulation of unconjugated bile acids and non-esterified very long-chain fatty acids PMID: 12810727
    7. hBAAT and rBaat are peroxisomal enzymes present in undetectable amounts in the cytosol. Unconjugated or deconjugated bile salts returning to the liver need to shuttle through the peroxisome before reentering the enterohepatic circulation. PMID: 17256745
    8. identification of 3 novel SNPs, 147C>T in exon 2 (silent), 602G>C in exon 3 (Arg201Pro) & 1134C>T in exon 4 (silent), in the BAAT gene by resequencing the entire coding region and the exon-intron junctions of 100 Japanese individuals PMID: 17495420
    9. Data show that dose-response inactivation by 4HNE (4-hydroxynonenal) of hBAT (human bile acid CoA:amino acid N-acyltransferase) and CKBB (cytosolic brain isoform of creatine kinase) is associated with site-specific modifications. PMID: 18793185

    顯示更多

    收起更多

  • 相關疾病：
    Familial hypercholanemia (FHCA)
  • 亞細胞定位：
    Cytoplasm, cytosol. Peroxisome.
  • 蛋白家族：
    C/M/P thioester hydrolase family
  • 組織特異性：
    Expressed in liver, gallbladder mucosa and pancreas.
  • 數據庫鏈接：

    HGNC: 932

    OMIM: 602938

    KEGG: hsa:570

    STRING: 9606.ENSP00000259407

    UniGene: Hs.284712



主站蜘蛛池模板： 3d动漫精品啪啪一区二区 | 中文无码一区二区三区在线观看| 国产乡下三级全黄三级| 日本内射精品一区二区视频| 丝袜无码专区人妻视频| 久久人人爽人人爽爽久久小说| 久久精品www人人做人人爽| 少妇扒开腿让我爽了一夜| 国产毛多水多高潮高清| 免费看女人与善牲交| 国产人妻精品一区二区三首| 国产成年无码久久久久毛片| 强开小婷嫩苞又嫩又紧视频| 日本在线观看| 人人爽久久涩噜噜噜av| 男女扒开双腿猛进入免费看污| 丰满少妇做爰视频爽爽和| 国产猛烈高潮尖叫视频免费| 8天堂资源在线| 久久精品人妻无码一区二区三区v| 欧洲丰满少妇a毛片| 人人狠狠综合久久亚洲爱咲| 国产免费永久精品无码| 日本道色综合久久影院| 亚洲旡码a∨一区二区三区| 国产亚洲精品久久77777| 国产色爱av资源综合区| 狠狠色综合网站久久久久久久| 亚洲国产天堂久久久久久| 国产精品调教视频一区| 成人精品视频99在线观看免费| 水蜜桃av无码| 亚洲日韩小电影在线观看| 久久精品手机观看| 特黄aaaaaaaaa毛片免费视频| 色婷婷综合久久久久中文一区二区| 欧美成人看片一区二三区图文| 国产做a爰片久久毛片a片美国| 中文字幕精品亚洲无线码一区| 777米奇影视第四色| 鲁鲁夜夜天天综合视频|